Pain in vulnerable people with chronic conditions: a multicentric cross-sectional study.

Sage open chronic disease Pub Date : 2026-04-07 eCollection Date: 2026-01-01 DOI:10.1177/27558428251336656
Charlotte Faurie, Demi Cheng, Claire Duflos, Liset Elstgeest, Rosanna Ferreira, Hein Raat, Verushka Valsecchi, Alberto Pilotto, Graham Baker, Marta M Pisano, Yves-Marie Pers
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Abstract

Background: Pain is a subjective, multidimensional experience modulated by emotional states and mental processes. It may be a source of major alterations in quality of life, and it represents substantial costs for health care systems and society.

Objectives: This research aims at exploring, in vulnerable persons living with chronic conditions, the relation between pain intensity and: (1) socio-demographic variables; (2) sedentary behaviour and physical exercise and (3) quality of life.

Design: The EFFICHRONIC intervention is part of the Third EU Health Programme. It consisted of implementing the Chronic Disease Self-Management Programme in five European regions (in France, Italy, Spain, the Netherlands and the United Kingdom).

Methods: Adjusting for a wide range of variables in multivariable regressions and using multiple imputation methods, we examined the associations between the intensity of pain and the other variables of interest in a large sample (1364 participants).

Results: These analyses showed that women had more intense pain, as well as participants with a lower education level. The pain was, among all variables, the main predictor of sleep problems, fatigue, depression, self-perceived health and quality of life.

Conclusion: Our results confirmed the importance of the social component in the complex aetiology of pain, and reinforced the idea that the recognition of the social determinants of health is essential. They are also in line with other studies showing the major impact of pain on an individual's health and life. Decreasing social inequalities and vulnerability could clearly reduce the prevalence of pain.

Trial registration: The study was registered at ISRCTN - The UK's Clinical Study Registry (70517103).

慢性疼痛易感人群:一项多中心横断面研究
背景:疼痛是一种由情绪状态和心理过程调节的主观、多维体验。它可能是生活质量发生重大变化的一个原因,它代表着卫生保健系统和社会的巨大成本。目的:本研究旨在探讨慢性疾病易感人群疼痛强度与以下因素的关系:(1)社会人口变量;(2)久坐行为和体育锻炼;(3)生活质量。设计:EFFICHRONIC干预措施是欧盟第三个卫生方案的一部分。它包括在五个欧洲区域(法国、意大利、西班牙、荷兰和联合王国)实施慢性病自我管理方案。方法:在多变量回归中调整广泛的变量,并使用多种归算方法,我们在一个大样本(1364名参与者)中检查了疼痛强度与其他感兴趣的变量之间的关系。结果:这些分析表明,女性和受教育程度较低的参与者有更强烈的疼痛。在所有变量中,疼痛是睡眠问题、疲劳、抑郁、自我感知健康和生活质量的主要预测因素。结论:我们的研究结果证实了社会因素在复杂的疼痛病因学中的重要性,并强化了认识到健康的社会决定因素是必不可少的这一观点。他们也与其他研究一致,表明疼痛对个人健康和生活的重大影响。减少社会不平等和脆弱性可以明显减少疼痛的流行。试验注册:该研究已在ISRCTN -英国临床研究注册中心注册(70517103)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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