Marta Gazzaneo, Athanasios Tyraskis, Laura Privitera, Stefano Giuliani, Dhanya Mullassery, Sonia Basson, Kate Cross, Simon Blackburn, Joseph Curry, Stavros P Loukogeorgakis, Simon Eaton, Paolo De Coppi
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引用次数: 0
Abstract
Background: Thoracoscopic patch repair of congenital diaphragmatic hernia (CDH) remains challenging for large defects, with no consensus on optimal patch fixation technique. This study evaluates outcomes of thoracoscopic patch repair stratified by defect size and suturing technique and compares them with primary thoracoscopic repair.
Methods: A retrospective review was performed of CDH patients undergoing thoracoscopic repair at a single tertiary centre (2019-2025). Primary outcomes were operative time and recurrence, stratified by defect size and suturing technique (interrupted vs. running), with secondary comparison with primary thoracoscopic repair.
Results: Of 63 patients undergoing thoracoscopic CDH repair, 46 (73%) had patch repair; 39 (61.9%) were completed thoracoscopically (conversion rate 11.1%). Among patients receiving a patch 69.2% (27/39) had type C or D defects. Mean operative time was 154.4 ± 33.5 min. Type D defects were associated with significantly longer operative times than type B (189 ± 25 vs. 142 ± 24 min; p = 0.03). Recurrence occurred in 3/39 (7.7%) patients at a mean follow-up of 17 months; no significant association with defect size was identified (p > 0.99). Suturing technique did not significantly influence operative time (interrupted vs. running: 164 ± 33 vs.153 ± 33 min; p = 0.39) or recurrence (1.4%vs.3.8% at quadrant-level analysis; p > 0.05). Recurrence rates were comparable between thoracoscopic patch and primary repair groups (7.7%vs.5.9%; p > 0.99).
Conclusions: Thoracoscopic patch repair of large CDH defects is feasible. Operative times and recurrence rate were comparable between suturing techniques. Larger multicentre studies are needed to validate these findings.
背景:胸腔镜下先天性膈疝补片修复术对于较大的缺损仍具有挑战性,对于最佳的补片固定技术尚无共识。本研究评估胸腔镜补片修补术的效果,并将其与初次胸腔镜修补术进行比较。方法:回顾性分析在单一三级中心(2019-2025)接受胸腔镜修复的CDH患者。主要结果是手术时间和复发率,根据缺陷大小和缝合技术(间断缝合与连续缝合)分层,并与首次胸腔镜修复进行二次比较。结果:63例胸腔镜CDH修复患者中,46例(73%)进行了补片修复;39例(61.9%)经胸腔镜完成,转换率为11.1%。在接受贴片的患者中,69.2%(27/39)存在C型或D型缺陷。平均手术时间154.4±33.5分钟。D型缺损的手术时间明显长于B型缺损(189±25 vs 142±24分钟;p = 0.03)。3/39(7.7%)例患者在平均随访17个月后出现复发;与缺陷大小没有显著的关联(p > 0.99)。缝合技术对手术时间(间断vs持续:164±33 vs 153±33分钟;p = 0.39)或复发率(象限水平分析1.4%vs.3.8%; p = 0.05)无显著影响。胸腔镜贴片组和初次修复组的复发率相当(7.7%vs 5.9%; p < 0.99)。结论:胸腔镜下修补大面积CDH缺损是可行的。两种缝合技术的手术时间和复发率具有可比性。需要更大规模的多中心研究来验证这些发现。
期刊介绍:
The journal presents original contributions as well as a complete international abstracts section and other special departments to provide the most current source of information and references in pediatric surgery. The journal is based on the need to improve the surgical care of infants and children, not only through advances in physiology, pathology and surgical techniques, but also by attention to the unique emotional and physical needs of the young patient.