Consenso argentino sobre la utilidad clínica de las pruebas de aire espirado y manejo del sobrecrecimiento microbiano intestinal en pacientes con trastornos de la interacción intestino-cerebro

IF 2 Q3 GASTROENTEROLOGY & HEPATOLOGY

Revista de Gastroenterologia de Mexico Pub Date : 2026-07-01 Epub Date: 2026-01-23 DOI:10.1016/j.rgmx.2025.11.003

L.O. Soifer, M.V. Contreras, F. Man, A. González-Flórez

{"title":"Consenso argentino sobre la utilidad clínica de las pruebas de aire espirado y manejo del sobrecrecimiento microbiano intestinal en pacientes con trastornos de la interacción intestino-cerebro","authors":"L.O. Soifer, M.V. Contreras, F. Man, A. González-Flórez","doi":"10.1016/j.rgmx.2025.11.003","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction and aim</h3><div>We present herein the results of a formal consensus meeting held in Argentina, whose aim was to analyze and discuss conceptual, technical, and clinical aspects related to the use of the breath test (BT) in the diagnosis and treatment of intestinal microbial overgrowth in patients with disorders of gut-brain interaction (DGBI).</div></div><div><h3>Material and methods</h3><div>Twelve healthcare professionals with experience in conducting BTs and treating patients with DGBI participated in an in-person meeting to discuss and vote on previously selected items.</div></div><div><h3>Results</h3><div>Of the 32 items discussed, 13 reached strong agreement and 10 reached relative agreement.</div></div><div><h3>Conclusions</h3><div>.</div><div>- The BT was considered a safe, useful tool in the approach to patients with DGBI.</div><div>- Application of the BT was also valuable in cases of irritable bowel syndrome with constipation.</div><div>- The simultaneous measurement of hydrogen (H<sub>2</sub>) and methane (CH4) is recommended.</div><div><strong>-</strong> A flat-line pattern should be considered suggestive of intestinal sulfide overproduction.</div><div>- Elevated baseline H<sub>2</sub> levels may reflect inadequate adherence to pre-test dietary preparation.</div><div>- A cutoff value of CH<sub>4</sub> ≥ 10ppm for diagnosing intestinal methanogen overgrowth should be considered.</div><div>- In patients with intestinal microbial overgrowth, the use of a nonabsorbable antibiotic, such as rifaximin, is recommended.</div><div>- The importance of registering patient symptoms during the test is strongly encouraged.</div></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 3","pages":"Pages 393-409"},"PeriodicalIF":2.0000,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista de Gastroenterologia de Mexico","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0375090625001867","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/23 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Introduction and aim

We present herein the results of a formal consensus meeting held in Argentina, whose aim was to analyze and discuss conceptual, technical, and clinical aspects related to the use of the breath test (BT) in the diagnosis and treatment of intestinal microbial overgrowth in patients with disorders of gut-brain interaction (DGBI).

Material and methods

Twelve healthcare professionals with experience in conducting BTs and treating patients with DGBI participated in an in-person meeting to discuss and vote on previously selected items.

Results

Of the 32 items discussed, 13 reached strong agreement and 10 reached relative agreement.

Conclusions

- The BT was considered a safe, useful tool in the approach to patients with DGBI.

- Application of the BT was also valuable in cases of irritable bowel syndrome with constipation.

- The simultaneous measurement of hydrogen (H₂) and methane (CH4) is recommended.

- A flat-line pattern should be considered suggestive of intestinal sulfide overproduction.

- Elevated baseline H₂ levels may reflect inadequate adherence to pre-test dietary preparation.

- A cutoff value of CH₄ ≥ 10 ppm for diagnosing intestinal methanogen overgrowth should be considered.

- In patients with intestinal microbial overgrowth, the use of a nonabsorbable antibiotic, such as rifaximin, is recommended.

- The importance of registering patient symptoms during the test is strongly encouraged.

查看原文本刊更多论文

关于呼出空气试验和管理肠-脑相互作用障碍患者肠道微生物过多的临床效用的阿根廷共识

我们在此介绍在阿根廷举行的正式共识会议的结果，其目的是分析和讨论与使用呼吸试验（BT）诊断和治疗肠-脑相互作用紊乱（DGBI）患者肠道微生物过度生长有关的概念、技术和临床方面。材料和方法12名具有实施bt和治疗DGBI患者经验的医疗保健专业人员参加了面对面会议，讨论和投票之前选定的项目。结果在讨论的32个项目中，13个达成强烈一致，10个达成相对一致。- BT被认为是治疗DGBI患者的一种安全、有用的工具。- BT在肠易激综合征伴便秘病例中的应用也很有价值。—建议同时测量氢气（H2）和甲烷（CH4）。-平线型应考虑提示肠道硫化物过量产生。-基线H2水平升高可能反映了测试前饮食准备的依从性不足。-诊断肠道产甲烷菌过度生长应考虑CH4≥10ppm的临界值。-对于肠道微生物过度生长的患者，建议使用不可吸收的抗生素，如利福昔明。-强烈建议在检测期间记录患者症状的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Revista de Gastroenterologia de Mexico GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

1.60

自引率

12.50%

发文量

102

审稿时长

12 weeks

期刊介绍： La Revista de Gastroenterología de México es el órgano oficial de la Asociación Mexicana de Gastroenterología. Sus espacios están abiertos a los miembros de la Asociación como a todo miembro de la comunidad médica que manifieste interés por utilizar este foro para publicar sus trabajos, cumpliendo con las políticas editoriales que a continuación se mencionan. El objetivo principal de la Revista de Gastroenterología de México, es publicar trabajos originales del amplio campo de la gastroenterología, así como proporcionar información actualizada y relevante para el área de la especialidad y áreas afines. Los trabajos científicos incluyen las áreas de Gastroenterología clínica, endoscópica, quirúrgica y pediátrica.