OA-02 A CD4 Dominant, T-Helper-Skewed T Cell State Underlies Movement and Neurocognitive Toxicity After BCMA-Directed CAR-T Therapy in Multiple Myeloma

IF 4.1 4区医学 Q2 HEMATOLOGY

Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2026-09-01 Epub Date: 2026-09-22 DOI:10.1016/S2152-2650(26)03304-5

Theresia Akhlaghi, Mateo Mejia Saldarriaga, David Jayabalan, Joshua Kassner, Frank Costanzo, Kameisha Gulgar, Christian Gordillo, Sarah Wesley, Roger Pearse, Giorgio Inghirami, Ran Reshef, Ruben Niesvizky, Mark Bustoros

引用次数: 0

查看原文本刊更多论文

在bcma指导下的多发性骨髓瘤CAR-T治疗后，OA-02 CD4显性、T辅助倾斜的T细胞状态是运动和神经认知毒性的基础

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Clinical Lymphoma, Myeloma & Leukemia ONCOLOGY-HEMATOLOGY

CiteScore

2.70

自引率

3.70%

发文量

1606

审稿时长

26 days

期刊介绍： Clinical Lymphoma, Myeloma & Leukemia is a peer-reviewed monthly journal that publishes original articles describing various aspects of clinical and translational research of lymphoma, myeloma and leukemia. Clinical Lymphoma, Myeloma & Leukemia is devoted to articles on detection, diagnosis, prevention, and treatment of lymphoma, myeloma, leukemia and related disorders including macroglobulinemia, amyloidosis, and plasma-cell dyscrasias. The main emphasis is on recent scientific developments in all areas related to lymphoma, myeloma and leukemia. Specific areas of interest include clinical research and mechanistic approaches; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; and integration of various approaches.