Assisting patients with reliable information gathering: A guide to building efficient QA systems for medical use.

IF 7.7
PLOS digital health Pub Date : 2026-09-17 eCollection Date: 2026-09-01 DOI:10.1371/journal.pdig.0001634
Zhipeng Yin, Zichong Wang, Min Chen, Ian Stockwell, Xin Ning, Jun Liu, Wenbin Zhang
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引用次数: 0

Abstract

The application of question-answering (QA) systems in the medical domain has rapidly advanced, significantly improving patients' access to reliable health-related information. However, current approaches face notable challenges, including the difficulty in obtaining large-scale and unbiased medical datasets, significant privacy concerns, and inefficiencies due to manual dataset annotation. To address these issues, This study introduce a novel methodology leveraging publicly accessible online health forums to systematically build an unbiased, privacy-conscious QA dataset, and it employs Topic-guided Semantic Modeling (TGSM) for automated topic identification, enabling efficient and targeted annotation of relevant patient-generated content. Subsequently, this study propose a two-stage QA pipeline based on a Retriever-Reader architecture, which is further enhanced through fine-tuning state-of-the-art transformer-based models on the constructed domain-specific QA dataset. Experimental results demonstrate that our fine-tuned BioBERT significantly outperforms existing benchmarks, offering accurate patient-derived insights and providing a replicable framework for building efficient medical QA systems.

协助患者收集可靠的信息:建立医疗用有效质量保证系统的指南。
问答(QA)系统在医疗领域的应用迅速发展,显著改善了患者获得可靠的健康相关信息的途径。然而,目前的方法面临着显著的挑战,包括难以获得大规模和无偏倚的医疗数据集,严重的隐私问题,以及由于手动数据集注释而导致的低效率。为了解决这些问题,本研究引入了一种新的方法,利用可公开访问的在线健康论坛,系统地构建一个公正的、具有隐私意识的QA数据集,并采用主题引导语义建模(TGSM)进行自动主题识别,从而对相关患者生成的内容进行高效和有针对性的注释。随后,本研究提出了一个基于检索-阅读器架构的两阶段QA管道,并通过在构建的特定领域QA数据集上微调最先进的基于变压器的模型来进一步增强该管道。实验结果表明,我们的微调BioBERT显著优于现有的基准,提供准确的患者衍生见解,并为构建高效的医疗质量保证系统提供可复制的框架。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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