The economic burden of functional neurological disorder.

IF 4.7
Siddhartha Bandyopadhyay, Joanne L Baker, Jisan Afrin
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Abstract

We provide an analysis of the economic burden of functional neurological disorder (FND). For a condition that is complex to diagnose and treat, estimating its true prevalence and incidence can be challenging. This estimation challenge has economic implications in terms of directing healthcare and other resources to mitigate the burden of FND. Existing economic analysis is limited, with most studies ignoring the wider social costs of FND, which are believed to be considerably higher than direct healthcare costs. This, in turn, affects the reliability of cost-effectiveness analysis. Using a number of existing studies, we provide an analysis of some of the challenges in estimating the true costs of FND. We revisit the debate around the appropriateness of cost-effectiveness analysis using quality-adjusted life years (QALYs) versus other frameworks, particularly generalised risk-adjusted cost-effectiveness (GRACE), in diseases like FND and its equity implications. Finally, we discuss how the probable underestimation of the economic burden of FND stifles innovation and dampens investment in promising technology. This article is part of the discussion meeting issue 'Digital healthcare for the management of functional neurological disorders'.

功能性神经障碍的经济负担。
我们对功能性神经障碍(FND)的经济负担进行了分析。对于一种诊断和治疗复杂的疾病,估计其真实患病率和发病率可能具有挑战性。这一估算挑战在指导医疗保健和其他资源以减轻FND负担方面具有经济意义。现有的经济分析是有限的,大多数研究忽略了FND的更广泛的社会成本,这被认为比直接医疗成本要高得多。这反过来又影响了成本效益分析的可靠性。利用一些现有的研究,我们分析了估算FND真实成本的一些挑战。我们重新讨论了在FND等疾病中使用质量调整生命年(QALYs)与其他框架(特别是广义风险调整成本效益(GRACE))进行成本效益分析的适当性及其公平性影响。最后,我们讨论了对FND经济负担的可能低估如何抑制创新和抑制对有前途的技术的投资。本文是讨论会议“功能性神经疾病管理的数字医疗保健”的一部分。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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