Electron Paramagnetic Resonance Method: Methemoglobin in Blood of Patients with Undifferentiated Connective Tissue Dyplasia

IF 0.48 Q4 Physics and Astronomy

Bulletin of the Russian Academy of Sciences: Physics Pub Date : 2026-09-14 DOI:10.1134/S1062873826701455

M. I. Ibragimova, A. I. Chushnikov, I. V. Yatsyk, D. Kh. Khaibullina, G. G. Gumarov

引用次数: 0

Abstract

Blood samples from patients with undifferentiated connective tissue dysplasia (UCTD) associated with back pain were analyzed using X-band EPR at temperatures ranging from 5 to 80 K. It was found that even moderate UCTD exhibits elevated methemoglobin and erythrocyte catalase concentrations. In severe UCTD, high methemoglobin concentrations and low transferrin levels are detected in the blood. As a result of computer modeling, it was established that the EPR spectra of blood samples from patients with UCTD and volunteers (control) are described by the same set of parameters, differing mainly only in the intensities of the components.

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电子顺磁共振法测定未分化结缔组织发育不良患者血液中高铁血红蛋白

使用x波段EPR对伴有背痛的未分化结缔组织发育不良（UCTD）患者的血液样本进行分析，温度范围为5至80 K。结果发现，即使是中度UCTD也表现出高铁血红蛋白和红细胞过氧化氢酶浓度升高。在严重的UCTD中，血液中检测到高铁血红蛋白浓度和低转铁蛋白水平。计算机建模的结果表明，UCTD患者和志愿者（对照组）血液样本的EPR谱由同一组参数描述，主要区别在于成分的强度。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Bulletin of the Russian Academy of Sciences: Physics Physics and Astronomy-Physics and Astronomy (all)

CiteScore

0.90

自引率

0.00%

发文量

251

期刊介绍： Bulletin of the Russian Academy of Sciences: Physics is an international peer reviewed journal published with the participation of the Russian Academy of Sciences. It presents full-text articles (regular, letters to the editor, reviews) with the most recent results in miscellaneous fields of physics and astronomy: nuclear physics, cosmic rays, condensed matter physics, plasma physics, optics and photonics, nanotechnologies, solar and astrophysics, physical applications in material sciences, life sciences, etc. Bulletin of the Russian Academy of Sciences: Physics focuses on the most relevant multidisciplinary topics in natural sciences, both fundamental and applied. Manuscripts can be submitted in Russian and English languages and are subject to peer review. Accepted articles are usually combined in thematic issues on certain topics according to the journal editorial policy. Authors featured in the journal represent renowned scientific laboratories and institutes from different countries, including large international collaborations. There are globally recognized researchers among the authors: Nobel laureates and recipients of other awards, and members of national academies of sciences and international scientific societies.