Bioplating demonstrates increasing micromovement during cyclic loading after anterior closed wedge high tibial osteotomy despite no significant difference in failure load compared to angle-stable plate fixation
Andrzej Jasina, Pia Metje, Jan-Oliver Sass, Jessica Hembus, Sjard Simons, Sina Gräber, Kira Liebau, Rainer Bader, Philipp Schuster, Maeruan Kebbach, Parisa Pourostad, Christoph Lutter, Felix Ferner
{"title":"Bioplating demonstrates increasing micromovement during cyclic loading after anterior closed wedge high tibial osteotomy despite no significant difference in failure load compared to angle-stable plate fixation","authors":"Andrzej Jasina, Pia Metje, Jan-Oliver Sass, Jessica Hembus, Sjard Simons, Sina Gräber, Kira Liebau, Rainer Bader, Philipp Schuster, Maeruan Kebbach, Parisa Pourostad, Christoph Lutter, Felix Ferner","doi":"10.1002/jeo2.70911","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Purpose</h3>\n \n <p>To biomechanically compare fixation stability after anterior closed wedge high tibial osteotomy (ACW-HTO) for posterior tibial slope (PTS) correction using trans-tuberosity “bioplating” and infra-tuberosity angle-stable plate fixation.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>In this cadaveric biomechanical study, fresh-frozen human knee specimens were allocated in a paired donor-matched manner to the two intervention groups. Tensile load was applied to the quadriceps tendon at a fixed flexion angle using an electrodynamic testing machine. After preloading, 1000 load cycles between 50 N and 200 N were performed at 1 Hz. The specimens were then loaded to failure at 10 mm/s. Micromovement at the osteotomy gap was analysed after 200 and 800 cycles using an optical 3D system. Two-way ANOVA with Bonferroni multiple comparison testing was used, with <i>p</i> < 0.05 considered statistically significant.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Twelve cadaveric knee specimens (<i>n</i> = 6 per intervention group; mean age 79.2 ± 8.2 years) were included. No statistically significant difference in micromovement was found between the two intervention groups after 200 (<i>p</i> = 0.515) or 800 cycles (<i>p</i> = 0.889). In the “bioplating” group, micromovement increased from 0.055 ± 0.017 mm after 200 cycles to 0.069 ± 0.035 mm after 800 cycles (<i>p</i> = 0.025), whereas no significant increase occurred with angle-stable fixation (<i>p</i> = 0.518). Osteosynthesis failure load did not differ significantly between groups (643.9 ± 190.8 N vs. 566.8 ± 111.0 N, <i>p</i> = 0.422).</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>No significant difference in failure load was detected between the techniques. However, “bioplating” demonstrated increasing micromovement during cyclic loading. Considering the limitations of the present biomechanical setup, superiority or inferiority of either fixation technique cannot be concluded. These findings should serve as a basis for further biomechanical testing and should be considered when selecting the surgical technique and postoperative treatment regimen in patients undergoing ACW-HTO for PTS correction.</p>\n </section>\n \n <section>\n \n <h3> Level of Evidence</h3>\n \n <p>Level V, controlled laboratory study.</p>\n </section>\n </div>","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"13 3","pages":""},"PeriodicalIF":3.2000,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jeo2.70911","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Experimental Orthopaedics","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jeo2.70911","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose
To biomechanically compare fixation stability after anterior closed wedge high tibial osteotomy (ACW-HTO) for posterior tibial slope (PTS) correction using trans-tuberosity “bioplating” and infra-tuberosity angle-stable plate fixation.
Methods
In this cadaveric biomechanical study, fresh-frozen human knee specimens were allocated in a paired donor-matched manner to the two intervention groups. Tensile load was applied to the quadriceps tendon at a fixed flexion angle using an electrodynamic testing machine. After preloading, 1000 load cycles between 50 N and 200 N were performed at 1 Hz. The specimens were then loaded to failure at 10 mm/s. Micromovement at the osteotomy gap was analysed after 200 and 800 cycles using an optical 3D system. Two-way ANOVA with Bonferroni multiple comparison testing was used, with p < 0.05 considered statistically significant.
Results
Twelve cadaveric knee specimens (n = 6 per intervention group; mean age 79.2 ± 8.2 years) were included. No statistically significant difference in micromovement was found between the two intervention groups after 200 (p = 0.515) or 800 cycles (p = 0.889). In the “bioplating” group, micromovement increased from 0.055 ± 0.017 mm after 200 cycles to 0.069 ± 0.035 mm after 800 cycles (p = 0.025), whereas no significant increase occurred with angle-stable fixation (p = 0.518). Osteosynthesis failure load did not differ significantly between groups (643.9 ± 190.8 N vs. 566.8 ± 111.0 N, p = 0.422).
Conclusion
No significant difference in failure load was detected between the techniques. However, “bioplating” demonstrated increasing micromovement during cyclic loading. Considering the limitations of the present biomechanical setup, superiority or inferiority of either fixation technique cannot be concluded. These findings should serve as a basis for further biomechanical testing and should be considered when selecting the surgical technique and postoperative treatment regimen in patients undergoing ACW-HTO for PTS correction.
目的比较前路闭合楔形胫骨高位截骨术(ACW-HTO)经结节“生物镀”和结节下角度稳定钢板固定后胫骨后坡(PTS)的生物力学稳定性。方法在尸体生物力学研究中,将新鲜冷冻的人体膝关节标本按配对供体匹配的方式分配到两个干预组。使用电动试验机以固定屈曲角度对股四头肌肌腱施加拉伸载荷。预加载后,以1hz的频率在50 N ~ 200 N之间进行1000次加载循环。然后以10 mm/s的速度加载试件直至破坏。使用光学3D系统分析200和800次循环后截骨间隙的微运动。采用Bonferroni多重比较检验的双因素方差分析,以p <; 0.05为差异有统计学意义。结果12例尸体膝关节标本,每干预组6例,平均年龄79.2±8.2岁。两组治疗200周(p = 0.515)和800周(p = 0.889)后微动差异无统计学意义。生物镀组的微动从200次循环后的0.055±0.017 mm增加到800次循环后的0.069±0.035 mm (p = 0.025),而角度稳定固定组的微动无显著增加(p = 0.518)。两组间骨整合失败负荷差异无统计学意义(643.9±190.8 N vs 566.8±111.0 N, p = 0.422)。结论两种技术在故障负荷上无显著差异。然而,“生物电镀”在循环加载过程中表现出微运动增加。考虑到目前生物力学装置的局限性,两种固定技术的优劣还不能下结论。这些发现应作为进一步生物力学测试的基础,并应在选择ACW-HTO患者进行PTS矫正的手术技术和术后治疗方案时予以考虑。证据等级V级,实验室对照研究。