Bioplating demonstrates increasing micromovement during cyclic loading after anterior closed wedge high tibial osteotomy despite no significant difference in failure load compared to angle-stable plate fixation

IF 3.2 Q2 ORTHOPEDICS
Andrzej Jasina, Pia Metje, Jan-Oliver Sass, Jessica Hembus, Sjard Simons, Sina Gräber, Kira Liebau, Rainer Bader, Philipp Schuster, Maeruan Kebbach, Parisa Pourostad, Christoph Lutter, Felix Ferner
{"title":"Bioplating demonstrates increasing micromovement during cyclic loading after anterior closed wedge high tibial osteotomy despite no significant difference in failure load compared to angle-stable plate fixation","authors":"Andrzej Jasina,&nbsp;Pia Metje,&nbsp;Jan-Oliver Sass,&nbsp;Jessica Hembus,&nbsp;Sjard Simons,&nbsp;Sina Gräber,&nbsp;Kira Liebau,&nbsp;Rainer Bader,&nbsp;Philipp Schuster,&nbsp;Maeruan Kebbach,&nbsp;Parisa Pourostad,&nbsp;Christoph Lutter,&nbsp;Felix Ferner","doi":"10.1002/jeo2.70911","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Purpose</h3>\n \n <p>To biomechanically compare fixation stability after anterior closed wedge high tibial osteotomy (ACW-HTO) for posterior tibial slope (PTS) correction using trans-tuberosity “bioplating” and infra-tuberosity angle-stable plate fixation.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>In this cadaveric biomechanical study, fresh-frozen human knee specimens were allocated in a paired donor-matched manner to the two intervention groups. Tensile load was applied to the quadriceps tendon at a fixed flexion angle using an electrodynamic testing machine. After preloading, 1000 load cycles between 50 N and 200 N were performed at 1 Hz. The specimens were then loaded to failure at 10 mm/s. Micromovement at the osteotomy gap was analysed after 200 and 800 cycles using an optical 3D system. Two-way ANOVA with Bonferroni multiple comparison testing was used, with <i>p</i> &lt; 0.05 considered statistically significant.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Twelve cadaveric knee specimens (<i>n</i> = 6 per intervention group; mean age 79.2 ± 8.2 years) were included. No statistically significant difference in micromovement was found between the two intervention groups after 200 (<i>p</i> = 0.515) or 800 cycles (<i>p</i> = 0.889). In the “bioplating” group, micromovement increased from 0.055 ± 0.017 mm after 200 cycles to 0.069 ± 0.035 mm after 800 cycles (<i>p</i> = 0.025), whereas no significant increase occurred with angle-stable fixation (<i>p</i> = 0.518). Osteosynthesis failure load did not differ significantly between groups (643.9 ± 190.8 N vs. 566.8 ± 111.0 N, <i>p</i> = 0.422).</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>No significant difference in failure load was detected between the techniques. However, “bioplating” demonstrated increasing micromovement during cyclic loading. Considering the limitations of the present biomechanical setup, superiority or inferiority of either fixation technique cannot be concluded. These findings should serve as a basis for further biomechanical testing and should be considered when selecting the surgical technique and postoperative treatment regimen in patients undergoing ACW-HTO for PTS correction.</p>\n </section>\n \n <section>\n \n <h3> Level of Evidence</h3>\n \n <p>Level V, controlled laboratory study.</p>\n </section>\n </div>","PeriodicalId":36909,"journal":{"name":"Journal of Experimental Orthopaedics","volume":"13 3","pages":""},"PeriodicalIF":3.2000,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jeo2.70911","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Experimental Orthopaedics","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jeo2.70911","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
引用次数: 0

Abstract

Purpose

To biomechanically compare fixation stability after anterior closed wedge high tibial osteotomy (ACW-HTO) for posterior tibial slope (PTS) correction using trans-tuberosity “bioplating” and infra-tuberosity angle-stable plate fixation.

Methods

In this cadaveric biomechanical study, fresh-frozen human knee specimens were allocated in a paired donor-matched manner to the two intervention groups. Tensile load was applied to the quadriceps tendon at a fixed flexion angle using an electrodynamic testing machine. After preloading, 1000 load cycles between 50 N and 200 N were performed at 1 Hz. The specimens were then loaded to failure at 10 mm/s. Micromovement at the osteotomy gap was analysed after 200 and 800 cycles using an optical 3D system. Two-way ANOVA with Bonferroni multiple comparison testing was used, with p < 0.05 considered statistically significant.

Results

Twelve cadaveric knee specimens (n = 6 per intervention group; mean age 79.2 ± 8.2 years) were included. No statistically significant difference in micromovement was found between the two intervention groups after 200 (p = 0.515) or 800 cycles (p = 0.889). In the “bioplating” group, micromovement increased from 0.055 ± 0.017 mm after 200 cycles to 0.069 ± 0.035 mm after 800 cycles (p = 0.025), whereas no significant increase occurred with angle-stable fixation (p = 0.518). Osteosynthesis failure load did not differ significantly between groups (643.9 ± 190.8 N vs. 566.8 ± 111.0 N, p = 0.422).

Conclusion

No significant difference in failure load was detected between the techniques. However, “bioplating” demonstrated increasing micromovement during cyclic loading. Considering the limitations of the present biomechanical setup, superiority or inferiority of either fixation technique cannot be concluded. These findings should serve as a basis for further biomechanical testing and should be considered when selecting the surgical technique and postoperative treatment regimen in patients undergoing ACW-HTO for PTS correction.

Level of Evidence

Level V, controlled laboratory study.

生物电镀显示在前路闭合楔形高位胫骨截骨后循环加载期间微运动增加,尽管失效载荷与角度稳定钢板固定相比没有显著差异
目的比较前路闭合楔形胫骨高位截骨术(ACW-HTO)经结节“生物镀”和结节下角度稳定钢板固定后胫骨后坡(PTS)的生物力学稳定性。方法在尸体生物力学研究中,将新鲜冷冻的人体膝关节标本按配对供体匹配的方式分配到两个干预组。使用电动试验机以固定屈曲角度对股四头肌肌腱施加拉伸载荷。预加载后,以1hz的频率在50 N ~ 200 N之间进行1000次加载循环。然后以10 mm/s的速度加载试件直至破坏。使用光学3D系统分析200和800次循环后截骨间隙的微运动。采用Bonferroni多重比较检验的双因素方差分析,以p <; 0.05为差异有统计学意义。结果12例尸体膝关节标本,每干预组6例,平均年龄79.2±8.2岁。两组治疗200周(p = 0.515)和800周(p = 0.889)后微动差异无统计学意义。生物镀组的微动从200次循环后的0.055±0.017 mm增加到800次循环后的0.069±0.035 mm (p = 0.025),而角度稳定固定组的微动无显著增加(p = 0.518)。两组间骨整合失败负荷差异无统计学意义(643.9±190.8 N vs 566.8±111.0 N, p = 0.422)。结论两种技术在故障负荷上无显著差异。然而,“生物电镀”在循环加载过程中表现出微运动增加。考虑到目前生物力学装置的局限性,两种固定技术的优劣还不能下结论。这些发现应作为进一步生物力学测试的基础,并应在选择ACW-HTO患者进行PTS矫正的手术技术和术后治疗方案时予以考虑。证据等级V级,实验室对照研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Journal of Experimental Orthopaedics
Journal of Experimental Orthopaedics Medicine-Orthopedics and Sports Medicine
CiteScore
3.20
自引率
5.60%
发文量
114
审稿时长
13 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书