Mitral and tricuspid valve disease

Medicine (Abingdon, England : UK ed.) Pub Date : 2026-09-01 Epub Date: 2026-08-26 DOI:10.1016/j.mpmed.2026.06.011
Anna Reid, Serge Osula
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引用次数: 0

Abstract

Mitral stenosis (MS) has become less common in developed countries with the declining incidence of rheumatic fever but remains a major health problem worldwide. Atrial fibrillation is a common accompaniment and can trigger the onset of pulmonary oedema. Medical treatment aims to control atrial fibrillation and prevent thromboembolism. Individuals with symptoms and a valve area <1.5 cm2 should be considered for balloon valvuloplasty or surgical valve replacement. Mitral regurgitation (MR) is common; it is usually caused by degenerative disease of the valve or is secondary to underlying left ventricular dysfunction. The management depends on the aetiology. Individuals with severe degenerative MR should be offered valve repair before the onset of limiting symptoms or left ventricular dysfunction. Surgery for secondary MR should be considered in patients with severe MR undergoing coronary artery bypass grafting, and in carefully selected patients with severe MR and symptoms of breathlessness despite optimal medical therapy. Percutaneous and minimally invasive approaches can be used in some patients. Tricuspid regurgitation is commonly seen on echocardiography and, if moderate to severe, is associated with a poor prognosis.
二尖瓣和三尖瓣疾病
随着风湿热发病率的下降,二尖瓣狭窄(MS)在发达国家已经变得不那么常见,但仍然是世界范围内的一个主要健康问题。心房颤动是一种常见的伴发性疾病,可引发肺水肿。药物治疗的目的是控制房颤和预防血栓栓塞。有症状且瓣膜面积大于1.5 cm2的患者应考虑球囊瓣膜成形术或手术瓣膜置换术。二尖瓣反流(MR)是常见的;它通常是由瓣膜退行性疾病引起的,或者是继发于潜在的左心室功能障碍。治疗取决于病因。严重退行性MR患者应在出现限制性症状或左心室功能障碍前进行瓣膜修复。严重MR患者行冠状动脉旁路移植术时,以及经过精心挑选的严重MR患者,尽管接受了最佳的药物治疗,但仍有呼吸困难的症状,应考虑进行二次MR手术。一些患者可采用经皮微创入路。三尖瓣反流常见于超声心动图,如果中度至重度,则与预后不良有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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CiteScore
1.10
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