{"title":"Mitral and tricuspid valve disease","authors":"Anna Reid, Serge Osula","doi":"10.1016/j.mpmed.2026.06.011","DOIUrl":null,"url":null,"abstract":"<div><div>Mitral stenosis (MS) has become less common in developed countries with the declining incidence of rheumatic fever but remains a major health problem worldwide. Atrial fibrillation is a common accompaniment and can trigger the onset of pulmonary oedema. Medical treatment aims to control atrial fibrillation and prevent thromboembolism. Individuals with symptoms and a valve area <1.5 cm<sup>2</sup> should be considered for balloon valvuloplasty or surgical valve replacement. Mitral regurgitation (MR) is common; it is usually caused by degenerative disease of the valve or is secondary to underlying left ventricular dysfunction. The management depends on the aetiology. Individuals with severe degenerative MR should be offered valve repair before the onset of limiting symptoms or left ventricular dysfunction. Surgery for secondary MR should be considered in patients with severe MR undergoing coronary artery bypass grafting, and in carefully selected patients with severe MR and symptoms of breathlessness despite optimal medical therapy. Percutaneous and minimally invasive approaches can be used in some patients. Tricuspid regurgitation is commonly seen on echocardiography and, if moderate to severe, is associated with a poor prognosis.</div></div>","PeriodicalId":74157,"journal":{"name":"Medicine (Abingdon, England : UK ed.)","volume":"54 9","pages":"Pages 625-632"},"PeriodicalIF":0.0000,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicine (Abingdon, England : UK ed.)","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1357303926001714","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/8/26 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Mitral stenosis (MS) has become less common in developed countries with the declining incidence of rheumatic fever but remains a major health problem worldwide. Atrial fibrillation is a common accompaniment and can trigger the onset of pulmonary oedema. Medical treatment aims to control atrial fibrillation and prevent thromboembolism. Individuals with symptoms and a valve area <1.5 cm2 should be considered for balloon valvuloplasty or surgical valve replacement. Mitral regurgitation (MR) is common; it is usually caused by degenerative disease of the valve or is secondary to underlying left ventricular dysfunction. The management depends on the aetiology. Individuals with severe degenerative MR should be offered valve repair before the onset of limiting symptoms or left ventricular dysfunction. Surgery for secondary MR should be considered in patients with severe MR undergoing coronary artery bypass grafting, and in carefully selected patients with severe MR and symptoms of breathlessness despite optimal medical therapy. Percutaneous and minimally invasive approaches can be used in some patients. Tricuspid regurgitation is commonly seen on echocardiography and, if moderate to severe, is associated with a poor prognosis.