Zachary L Steinberg, Tara Krishnan, Lia M Barros, Jonathan Buber, Kelly D Smith, Michael S Mulligan, Peter J Leary, Samuel G Rayner
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引用次数: 0
Abstract
Balloon pulmonary angioplasty (BPA) has emerged as a guideline-recommended therapy for surgically inoperable chronic thromboembolic pulmonary hypertension (CTEPH). Lung injury occurs in approximately 6% of BPA sessions and is the leading cause of procedure-related mortality. While lung injury post-BPA has recently been associated with vascular injury and hemorrhage, pathologic evidence is lacking regarding whether injury is uniformly hemorrhagic or whether a permeability-mediated pattern, such as seen in reperfusion edema, predominates in some cases. We present a case of severe BPA-associated lung injury resulting in mortality, report the first histopathologic characterization of the parenchymal injury pattern in this setting, and describe how these findings informed successful rescue veno-arterial extracorporeal membrane oxygenation (VA-ECMO) in a second case.
期刊介绍：
Pulmonary Circulation''s main goal is to encourage basic, translational, and clinical research by investigators, physician-scientists, and clinicans, in the hope of increasing survival rates for pulmonary hypertension and other pulmonary vascular diseases worldwide, and developing new therapeutic approaches for the diseases. Freely available online, Pulmonary Circulation allows diverse knowledge of research, techniques, and case studies to reach a wide readership of specialists in order to improve patient care and treatment outcomes.
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