Variation in Treatment Patterns of Type 2 Diabetes in Older Patients.

IF 6.1 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Diabetes, Obesity & Metabolism Pub Date : 2026-11-01 Epub Date: 2026-08-23 DOI:10.1111/dom.71178
Phuc Le, Ning Guo, Anita Misra-Hebert, Christopher B Boyer, Kevin M Pantalone, Hamlet Gasoyan, Nicholas J Casacchia, Michael B Rothberg
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引用次数: 0

Abstract

Aims: To estimate the proportion of older patients with type 2 diabetes (T2D) and HbA1c above or below goal at provider level and explore factors associated with patients being above or below goal.

Materials and methods: We used 2023 Cleveland Clinic electronic health records, including patients ≥ 65 years old with T2D, ≥ 1 diabetes medication and ≥ 1 HbA1c measurement. Patients were assigned to their listed primary care provider or the one they saw most frequently and stratified into good, intermediate, or poor health. Outcomes were patients being above, at, and below goal, defined as HbA1c greater than, 0%-1.5% lower than, and ≥ 1.5% lower than goal, respectively. HbA1c goals were < 7.5% for patients with good, < 8% intermediate and < 9% poor health.

Results: We included 406 providers and 15 865 patients. Across providers, 52.1% (range: 10%-87.9%) of patients were below goal (13.4% in those with good, 42.0% intermediate, 76.0% poor health); 11.3% (range: 0.0%-36.4%) were above goal (25.1% in those with good, 13.7% intermediate, 6.7% poor health). There was significant variation across providers (p < 0.001). In a multivariable model, having endocrinology providers (vs. internal medicine) decreased the adjusted relative risk ratio (aRRR) of being below goal (aRRR = 0.69; 95% CI: 0.57-0.82) and increased the probability of being above goal (aRRR = 1.65; 95% CI: 1.33-2.05).

Conclusion: Substantial provider-level variation suggests that individualised glycemic management for older adults remains difficult to operationalise in routine care. Clinical decision support tools that automate assessment of health status and recommend glycemic goals may help clinicians better align glycemic management with patient needs.

老年2型糖尿病患者治疗模式的差异
目的:估计老年2型糖尿病患者(T2D)和HbA1c在提供者水平上高于或低于目标的比例,并探讨患者高于或低于目标的相关因素。材料和方法:我们使用2023份克利夫兰诊所的电子健康记录,包括年龄≥65岁的T2D患者,≥1次糖尿病药物治疗和≥1次HbA1c检测。患者被分配到他们列出的初级保健提供者或他们最常见到的提供者,并被分为健康状况良好、中等或较差。结果是患者的HbA1c高于、达到和低于目标,分别定义为HbA1c大于、低于目标0%-1.5%和低于目标≥1.5%。结果:我们纳入了406名提供者和15865名患者。在所有医疗机构中,52.1%(范围:10%-87.9%)的患者未达到目标(健康状况良好者占13.4%,健康状况中等者占42.0%,健康状况不佳者占76.0%);11.3%(范围:0.0% ~ 36.4%)高于目标(健康状况良好者为25.1%,中等健康者为13.7%,较差者为6.7%)。结论:大量提供者水平的差异表明,个性化的老年人血糖管理仍然难以在常规护理中实施。自动评估健康状况和推荐血糖目标的临床决策支持工具可以帮助临床医生更好地将血糖管理与患者需求结合起来。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Diabetes, Obesity & Metabolism
Diabetes, Obesity & Metabolism 医学-内分泌学与代谢
CiteScore
10.90
自引率
6.90%
发文量
319
审稿时长
3-8 weeks
期刊介绍: Diabetes, Obesity and Metabolism is primarily a journal of clinical and experimental pharmacology and therapeutics covering the interrelated areas of diabetes, obesity and metabolism. The journal prioritises high-quality original research that reports on the effects of new or existing therapies, including dietary, exercise and lifestyle (non-pharmacological) interventions, in any aspect of metabolic and endocrine disease, either in humans or animal and cellular systems. ‘Metabolism’ may relate to lipids, bone and drug metabolism, or broader aspects of endocrine dysfunction. Preclinical pharmacology, pharmacokinetic studies, meta-analyses and those addressing drug safety and tolerability are also highly suitable for publication in this journal. Original research may be published as a main paper or as a research letter.
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