The association between pubertal timing and diurnal cortisol activity in middle adolescence.

IF 3.7 4区心理学 Q2 BEHAVIORAL SCIENCES

Stress-The International Journal on the Biology of Stress Pub Date : 2026-12-31 Epub Date: 2026-08-15 DOI:10.1080/10253890.2026.2718133

Ellie Roberts, Eirini Flouri

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引用次数: 0

Abstract

The pubertal development stage is associated with mental health. One explanation is that the pubertal stage is linked to changes in hypothalamic‒pituitary‒adrenal (HPA) axis activity. However, no study has investigated the prospective association between pubertal timing and HPA axis activity, measured by cortisol, in middle adolescence. Using data from 914 individuals (54.70% female) from the Avon Longitudinal Study of Parents and Children (ALSPAC), the current study sought to determine whether pubertal timing across the ages of 8-15.5 years (measured by menarche for girls and voice breaking for boys) was associated with diurnal cortisol slope, the cortisol awakening response, total morning cortisol, and total daily cortisol output at the age of 15.5 years. In girls, earlier menarche was associated with higher (logged) cortisol awakening response (b = -.003; 95% CI = -.007, -.0004), but the association was significant only after adjustment for confounders, especially ethnicity. No associations were observed in boys.

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青春期中期青春期时间与皮质醇日活动的关系。

青春期发育阶段与心理健康有关。一种解释是，青春期与下丘脑-垂体-肾上腺轴（HPA）活动的变化有关。然而，没有研究调查青春期时间与青春期中期HPA轴活动之间的前瞻性关联。利用来自雅芳父母与儿童纵向研究（ALSPAC）的914名个体（54.70%为女性）的数据，本研究试图确定8-15.5岁之间的青春期时间（通过女孩的初潮和男孩的声音破裂来测量）是否与15.5岁时的日皮质醇斜率、皮质醇觉醒反应、早晨总皮质醇和每日总皮质醇输出有关。在女孩中，较早的初潮与较高的（记录的）皮质醇觉醒反应相关（b = - 0.003; 95% CI = - 0.007, - 0.0004），但只有在调整混杂因素，特别是种族因素后，这种关联才显着。在男孩中没有观察到关联。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Stress-The International Journal on the Biology of Stress 医学-行为科学

CiteScore

5.60

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The journal Stress aims to provide scientists involved in stress research with the possibility of reading a more integrated view of the field. Peer reviewed papers, invited reviews and short communications will deal with interdisciplinary aspects of stress in terms of: the mechanisms of stressful stimulation, including within and between individuals; the physiological and behavioural responses to stress, and their regulation, in both the short and long term; adaptive mechanisms, coping strategies and the pathological consequences of stress. Stress will publish the latest developments in physiology, neurobiology, molecular biology, genetics research, immunology, and behavioural studies as they impact on the understanding of stress and its adverse consequences and their amelioration. Specific approaches may include transgenic/knockout animals, developmental/programming studies, electrophysiology, histochemistry, neurochemistry, neuropharmacology, neuroanatomy, neuroimaging, endocrinology, autonomic physiology, immunology, chronic pain, ethological and other behavioural studies and clinical measures.