Managing severe gestational hypertension in Italy: a cost description.

IF 2.2 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES
Carlo Lazzaro, Giovanna Esposito, Anna Cantarutti, Francesco Parazzini, Giovanni Corrao, Matteo Franchi, Fabio Parazzini
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Abstract

Background: Gestational hypertension (GH) is a common complication that affects approximately 5% of pregnancies worldwide.

Research design and methods: Presenting a model-based cost description of managing severe GH in inward setting following the Italian National Health Service (INHS) perspective. Epidemiological data on pregnancies and severe GH were obtained from Lombardy region and extrapolated to national level for 2024 (last available year). Health care resources for managing severe GH patients aged 20-49 years, identified and quantified according to literature and expert' opinion, were valued through INHS tariffs (2025 values). One-way and scenario sensitivity analyses tested the robustness of the baseline findings.

Results: 375,553 pregnancies and 1928 episodes of severe GH needing hospitalization (0.51% of all pregnancies) were estimated for Italy in 2024. The overall average cost of managing a severe GH episode reaches €752.64. Inward hospitalization (€454.23) is the main cost-driver (60.04% of the total), as confirmed by one-way and scenario sensitivity analyses.

Conclusion: As reported in research conducted in other countries, inward hospitalization is both essential and the main cost-driver for the optimal management of severe GH. Outpatient programmes aimed at identifying and following-up GH patients before the disease requires hospitalization should be considered by INHS policymakers.

在意大利管理严重妊娠期高血压:成本描述。
背景:妊娠期高血压(GH)是一种常见的并发症,影响全世界约5%的妊娠。研究设计和方法:根据意大利国家卫生服务(INHS)的观点,提出了一种基于模型的成本描述,用于管理内部环境中的严重生长激素。从伦巴第地区获得了妊娠和严重生长激素的流行病学数据,并将其外推到2024年(最近可获得的年份)的全国水平。根据文献资料和专家意见,对20 ~ 49岁重症GH患者管理的卫生保健资源进行识别和量化,并通过INHS关税(2025值)进行评估。单向和情景敏感性分析检验了基线结果的稳健性。结果:2024年意大利估计有375,553例妊娠和1928例严重GH需要住院治疗(占所有妊娠的0.51%)。管理一次严重GH发作的总体平均费用达到752.64欧元。单向和情景敏感性分析证实,住院费用(454.23欧元)是主要的成本驱动因素(占总数的60.04%)。结论:根据其他国家的研究报告,对于重症GH的最佳管理,住院治疗既是必要的,也是主要的成本驱动因素。国家卫生和公众服务部的决策者应该考虑在疾病需要住院之前确定和随访GH患者的门诊方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Expert Review of Pharmacoeconomics & Outcomes Research
Expert Review of Pharmacoeconomics & Outcomes Research HEALTH CARE SCIENCES & SERVICES-PHARMACOLOGY & PHARMACY
CiteScore
4.00
自引率
4.30%
发文量
68
审稿时长
6-12 weeks
期刊介绍: Expert Review of Pharmacoeconomics & Outcomes Research (ISSN 1473-7167) provides expert reviews on cost-benefit and pharmacoeconomic issues relating to the clinical use of drugs and therapeutic approaches. Coverage includes pharmacoeconomics and quality-of-life research, therapeutic outcomes, evidence-based medicine and cost-benefit research. All articles are subject to rigorous peer-review. The journal adopts the unique Expert Review article format, offering a complete overview of current thinking in a key technology area, research or clinical practice, augmented by the following sections: Expert Opinion – a personal view of the data presented in the article, a discussion on the developments that are likely to be important in the future, and the avenues of research likely to become exciting as further studies yield more detailed results Article Highlights – an executive summary of the author’s most critical points.
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