Patrick Morhart, Sergio Antonio Maravilla-Galdamez, Petros Strempas, Thomas Bollinger, Thomas Kienbaum, Heidi Weberruß
{"title":"First Report on Neonatal Isolated Submandibular Suppurative Sialadenitis in Preterm Triplet Girls.","authors":"Patrick Morhart, Sergio Antonio Maravilla-Galdamez, Petros Strempas, Thomas Bollinger, Thomas Kienbaum, Heidi Weberruß","doi":"10.1155/crpe/4240104","DOIUrl":null,"url":null,"abstract":"<p><p>Neonatal isolated submandibular suppurative sialadenitis (NISSS) is a rare condition. We present a case of NISSS caused by <i>Staphylococcus aureus</i> (<i>S. aureus</i>) in premature triplet girls born at 28 + 1 weeks of gestation. Mother's milk culture tested positive for <i>S. aureus</i>, which is presumed to be the potential contributing factor of the infection. The first symptoms appeared in one of the girls at 31 days of age, followed by her sisters at 34 and 36 days of age, respectively. A search of the PubMed/Medline, ScienceDirect and Web of Science databases revealed that this is the first reported case of NISSS in triplets. We defined risk factors like an immature immune system, prolonged orogastric feeding and antidiuretic therapy for developing NISSS in neonates.</p>","PeriodicalId":9623,"journal":{"name":"Case Reports in Pediatrics","volume":"2026 ","pages":"4240104"},"PeriodicalIF":0.5000,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13451618/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Pediatrics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/crpe/4240104","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0
Abstract
Neonatal isolated submandibular suppurative sialadenitis (NISSS) is a rare condition. We present a case of NISSS caused by Staphylococcus aureus (S. aureus) in premature triplet girls born at 28 + 1 weeks of gestation. Mother's milk culture tested positive for S. aureus, which is presumed to be the potential contributing factor of the infection. The first symptoms appeared in one of the girls at 31 days of age, followed by her sisters at 34 and 36 days of age, respectively. A search of the PubMed/Medline, ScienceDirect and Web of Science databases revealed that this is the first reported case of NISSS in triplets. We defined risk factors like an immature immune system, prolonged orogastric feeding and antidiuretic therapy for developing NISSS in neonates.
摘要新生儿孤立性下颌骨化脓性涎腺炎是一种罕见的疾病。我们报告一例由金黄色葡萄球菌(金黄色葡萄球菌)引起的妊娠28 + 1周出生的早产三胞胎女孩niss。母乳培养对金黄色葡萄球菌检测呈阳性,这被认为是感染的潜在因素。其中一名女孩在31日龄时首次出现症状,随后她的姐妹分别在34和36日龄时出现症状。对PubMed/Medline、ScienceDirect和Web of Science数据库的搜索显示,这是三胞胎中首次报道的niss病例。我们确定了发生新生儿niss的危险因素,如不成熟的免疫系统、长时间的胃喂养和抗利尿剂治疗。