Application of a Domestic Chinese Robotic Surgical System in Radical Resection Combined With Lateral Lymph Node Dissection for Low Rectal Cancer: A Retrospective Study

IF 2.7 3区医学 Q2 ONCOLOGY

Clinical colorectal cancer Pub Date : 2026-09-01 Epub Date: 2026-07-09 DOI:10.1016/j.clcc.2026.07.002

Feng Zheng, Aihe Sun, Peng Zhai, Zhongming Bao, Yongjun Jiang

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引用次数: 0

Abstract

Introduction

Lateral lymph node dissection (LLND) in low rectal cancer is technically demanding due to the narrow pelvis and risk of nerve injury. Robotic surgery may improve visualization and precision, but evidence on domestic Chinese robotic systems for this procedure is limited. This study compared the safety and short-term outcomes of the KangDuo Surgical Robot-01 (KD-SR-01) robotic system with conventional laparoscopic surgery in patients undergoing radical resection with LLND.

Patients and Methods

This retrospective single-center study included 278 patients with low rectal cancer who underwent radical resection plus LLND from June 2022 to June 2025. Patients were divided into robotic (n = 120, KangDuo KD-SR-01) and laparoscopic (n = 158) groups. Perioperative, pathological, postoperative, and short-term oncological outcomes were compared.

Results

Baseline characteristics were comparable between groups. After 1:1 propensity score matching (119 pairs), the robotic group showed significantly shorter total operation time (238.7 ± 45.9 vs. 304.1 ± 58.9 minutes, P < .001), shorter LLND time (86.5 ± 23.2 vs. 121.1 ± 27.2 minutes, P < .001), lower blood loss (134.5 ± 52.3 vs. 351.8 ± 183.2 mL, P < .001), and higher lateral lymph node yield (7.87 ± 2.19 vs. 5.87 ± 2.34, P < .001) compared with the laparoscopic group. These advantages persisted in the matched cohort. Robotic surgery was also associated with, borderline lower overall complication rate (P = .047), and nominally lower sexual dysfunction (P = .047). Pathological outcomes and DFS (log-rank P = .163) were comparable.

Conclusion

The domestic KangDuo KD-SR-01 robotic system is safe and feasible for radical resection with LLND in low rectal cancer. It provides significant perioperative and functional benefits compared to laparoscopy without compromising short-term oncological results.

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国产机器人手术系统在低位直肠癌根治性切除联合侧淋巴结清扫中的应用：回顾性研究。

由于骨盆狭窄和神经损伤的风险，低位直肠癌的侧淋巴结清扫术（LLND）在技术上要求很高。机器人手术可以提高可视化和精度，但国内机器人系统在这一过程中的证据有限。本研究比较了KangDuo Surgical Robot-01 （KD-SR-01）机器人系统与传统腹腔镜手术在LLND根治性切除患者中的安全性和短期疗效。患者和方法：这项回顾性单中心研究纳入了2022年6月至2025年6月期间接受根治性切除加LLND治疗的278例低位直肠癌患者。患者分为机器人组（n = 120，康多KD-SR-01）和腹腔镜组（n = 158）。比较围手术期、病理、术后和短期肿瘤预后。结果：两组间基线特征具有可比性。经1:1倾向评分匹配（119对）后，机器人组与腹腔镜组相比，总手术时间（238.7±45.9 vs 304.1±58.9 min, P < 0.001）、LLND时间（86.5±23.2 vs 121.1±27.2 min, P < 0.001）、出血量（134.5±52.3 vs 351.8±183.2 mL, P < 0.001）、外侧淋巴结清扫率（7.87±2.19 vs 5.87±2.34,P < 0.001）显著缩短。这些优势在匹配的队列中持续存在。机器人手术也与较低的总体并发症发生率（P = 0.047）和名义上较低的性功能障碍（P = 0.047）相关。病理结果和DFS （log-rank P = .163）具有可比性。结论：国产康多KD-SR-01机器人系统用于低位直肠癌LLND根治术是安全可行的。与腹腔镜相比，它提供了显著的围手术期和功能优势，而不会影响短期肿瘤结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical colorectal cancer 医学-肿瘤学

CiteScore

5.50

自引率

2.90%

发文量

审稿时长

27 days

期刊介绍： Clinical Colorectal Cancer is a peer-reviewed, quarterly journal that publishes original articles describing various aspects of clinical and translational research of gastrointestinal cancers. Clinical Colorectal Cancer is devoted to articles on detection, diagnosis, prevention, and treatment of colorectal, pancreatic, liver, and other gastrointestinal cancers. The main emphasis is on recent scientific developments in all areas related to gastrointestinal cancers. Specific areas of interest include clinical research and mechanistic approaches; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; and integration of various approaches.