Effect of Resin, Calcium Silicate, and Silicone-Based Root Canal Sealers on Postoperative Pain: A Randomized Controlled Clinical Trial.

Q4 Dentistry

Journal of Dental Research, Dental Clinics, Dental Prospects Pub Date : 2026-03-30 eCollection Date: 2026-03-01 DOI:10.34172/joddd.42747

Gizem Kadı, Esin Özlek

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引用次数: 0

Abstract

Introduction: This study aimed to compare the effects of resin- (AH Plus), calcium silicate- (iRoot SP), and silicone-based (GuttaFlow Bioseal) root canal sealers on postoperative pain.

Methods: This study included 84 patients with mandibular molars diagnosed with irreversible pulpitis. Root canal shaping procedures were completed using X-Smart Plus (Dentsply Maillefer, Ballaigues, Switzerland) endodontic motor and EndoArt (İnci Dental, İstanbul, Turkey) nickel-titanium rotary system up to #25 (30.06) shaping file for mesial root anals and #30 (0.6) shaping file for root distal canals. The patients were randomly divided into 3 groups based on the root canal sealer used (n=28): group 1: AH Plus, group 2: iRoot SP, and group 3: GuttaFlow Bioseal. Pain scores were recorded using a visual analog scale (VAS) before and after treatment at the 6th, 24th, 48th, and 72nd hours, and at the first week. Additionally, the frequency and timing of analgesic intake were recorded. The chi-squared test was used for categorical variables. The Kruskal-Wallis test was used to compare differences in non-normally distributed continuous data between groups. The Friedman test was used to compare pain scores over time within each group, and the Cochran's Q test was used to analyze analgesic use.

Results: No statistically significant differences in median VAS scores were found at various time intervals between the groups (P>0.05). Analgesic use distribution at the 6th (P=0.658) and the 24th (P=0.355) hours also did not show significant differences between the groups.

Conclusion: Resin-, bioceramic-, or silicone-based sealers showed similar effects on postoperative pain.

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树脂、硅酸钙和硅基根管密封剂对术后疼痛的影响：一项随机对照临床试验。

本研究旨在比较树脂- (AH Plus)、硅酸钙- (iRoot SP)和硅基（GuttaFlow Bioseal）根管密封剂对术后疼痛的影响。方法：对84例诊断为不可逆性牙髓炎的下颌磨牙患者进行研究。根管整形手术使用X-Smart Plus （Dentsply Maillefer, Ballaigues, Switzerland）根管电机和EndoArt （İnci Dental， İstanbul，土耳其）镍钛旋转系统完成，近端根管采用25号（30.06）整形锉，远端根管采用30号（0.6）整形锉。根据患者使用的根管密封剂随机分为3组（n=28）： 1组：AH Plus， 2组：iRoot SP， 3组：GuttaFlow Bioseal。分别于治疗前、治疗后第6、24、48、72小时及第1周采用视觉模拟评分法（VAS）记录疼痛评分。此外，记录镇痛药摄入的频率和时间。分类变量采用卡方检验。采用Kruskal-Wallis检验比较组间非正态分布连续数据的差异。弗里德曼测试用于比较各组疼痛评分随时间的变化，科克伦Q测试用于分析止痛药的使用情况。结果：各组VAS中位评分各时间间隔差异无统计学意义（P < 0.05）。第6 h （P=0.658）和第24 h （P=0.355）组间镇痛药使用分布差异无统计学意义。结论：树脂、生物陶瓷或硅基密封剂对术后疼痛的效果相似。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Dental Research, Dental Clinics, Dental Prospects Dentistry-General Dentistry

CiteScore

1.40

自引率

0.00%

发文量

审稿时长

25 weeks

期刊介绍： Journal of Dental Research Dental Clinics Dental Prospects (JODDD) is a Platinum* Open Access, peer-reviewed quarterly indexed journal that publishes articles of basic, clinical, and prospective nature in all areas of dentistry and oral health.