A Prediction Model for One-Year Disability Risk Among Community-Dwelling Older Adults in China: Integrating Physical, Metabolic, and Psychosocial Factors

IF 6
Health Care Science Pub Date : 2026-08-11 Epub Date: 2026-05-17 DOI:10.1002/hcs2.70080
Yanjun Ma, Chaofan Geng, Zhibin Wang, Yiwei Zhao, Lixin Ma, Pengpeng Ye, Leilei Duan, Guoping Peng, Yi Tang
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引用次数: 0

Abstract

Background

Disability in older adults, characterized by progressive limitations in performing activities of daily living, poses a significant public health challenge in aging societies. Early identification of individuals at risk is critical for implementing targeted interventions to mitigate functional decline. However, existing prediction models often prioritize disease-related physiological indicators and overlook psychosocial dimensions, limiting their practicality and scalability in community-based settings. This study aimed to develop and validate a practicable prediction model for 1-year disability risk by integrating multidimensional indicators.

Methods

A prospective community-based cohort in Beijing, functionally independent at baseline, was followed for 1 year. Disability was defined as a decline in the Barthel Index score. Potential predictors included demographic, lifestyle, clinical, physical, and psychosocial measures. The least absolute shrinkage and selection operator (LASSO) regression was used for variable selection, followed by logistic regression to construct the final model. Model performance was evaluated through fivefold cross-validation repeated 100 times, with assessment of discrimination and calibration.

Results

Among 1003 community-dwelling older adults (mean age 68.4 ± 5.2 years; 58.3% female), 163 (16.3%) developed disability at follow-up. The LASSO regression identified seven predictors: age, dyslipidemia, gait speed, waist circumference, difficulty in lifting weights, appetite, and emotion regulation ability. The model demonstrated moderate discrimination, with an area under the receiver operating characteristic curve of 0.716 (95% CI: 0.712–0.720). Calibration curves indicated good overall agreement between predicted and observed risks. A nomogram was developed to facilitate individualized risk prediction in clinical practice.

Conclusions

This study presents a practical disability risk prediction model incorporating physical, metabolic, and psychosocial factors. The model exhibits acceptable discrimination and calibration, supporting its potential for early screening and stratified management of community-dwelling older adults. Future multicenter validations are warranted to enhance generalizability and explore dynamic interventions targeting modifiable factors like emotion regulation and gait speed.

Abstract Image

中国社区居住老年人一年残疾风险预测模型:综合身体、代谢和社会心理因素
背景:老年人残疾的特点是日常生活活动逐渐受到限制,这对老龄化社会的公共卫生构成了重大挑战。早期识别有风险的个体对于实施有针对性的干预措施以减轻功能衰退至关重要。然而,现有的预测模型往往优先考虑与疾病相关的生理指标,而忽视社会心理维度,限制了它们在社区环境中的实用性和可扩展性。本研究旨在通过多维指标的整合,建立并验证一个可行的1年残疾风险预测模型。方法:北京一个前瞻性社区队列,基线时功能独立,随访1年。残疾被定义为Barthel指数得分的下降。潜在的预测因素包括人口统计、生活方式、临床、生理和社会心理测量。使用最小绝对收缩和选择算子(LASSO)回归进行变量选择,然后使用逻辑回归构建最终模型。通过重复100次的五重交叉验证来评估模型的性能,并评估识别和校准。结果:1003名社区老年人(平均年龄68.4±5.2岁,女性58.3%)中,163名(16.3%)在随访中出现残疾。LASSO回归确定了七个预测因素:年龄、血脂异常、步态速度、腰围、举重难度、食欲和情绪调节能力。该模型具有中等判别能力,受试者工作特征曲线下面积为0.716 (95% CI: 0.712-0.720)。校准曲线显示预测风险与观测风险总体上吻合良好。在临床实践中,开发了一种nomogram方法来促进个体化的风险预测。结论:本研究提出了一种结合身体、代谢和社会心理因素的实用残疾风险预测模型。该模型显示出可接受的区分和校准,支持其对社区居住老年人的早期筛查和分层管理的潜力。未来的多中心验证有必要增强泛化性,并探索针对情绪调节和步态速度等可变因素的动态干预措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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