Brain Activity of Young Children in Bangladesh Is Associated With Biopsychosocial Conditions at the Individual-, Family-, and Household-Level

IF 2.4 2区心理学 Q3 PSYCHOLOGY, DEVELOPMENTAL

Infancy Pub Date : 2026-07-18 DOI:10.1111/infa.70108

Leila M. Larson, Daniel Feuerriegel, Gitanjali Lall, Mohammed Imrul Hasan, Sabine Braat, Jerry Jin, Beverley-Ann Biggs, Stefan Bode, Sant-Rayn Pasricha, Katherine A. Johnson, Jena D. Hamadani

{"title":"Brain Activity of Young Children in Bangladesh Is Associated With Biopsychosocial Conditions at the Individual-, Family-, and Household-Level","authors":"Leila M. Larson, Daniel Feuerriegel, Gitanjali Lall, Mohammed Imrul Hasan, Sabine Braat, Jerry Jin, Beverley-Ann Biggs, Stefan Bode, Sant-Rayn Pasricha, Katherine A. Johnson, Jena D. Hamadani","doi":"10.1111/infa.70108","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <p>Adversities in early life compromise children's nurturing care and impact their development. This study explored the biopsychosocial conditions associated with electroencephalography (EEG)-based brain activity in children living in rural Bangladesh, a setting with high rates of malnutrition and suboptimal psychosocial stimulation. In a substudy of the Benefits and Risks of Iron Supplementation in Children (BRISC) study in Bangladesh, we recorded resting EEG brain activity in a random subsample of 440 children at 11 months and 594 children at 20 months of age. EEG band power measures were derived for delta, theta, alpha, and beta power bands. Validated tools were used to assess maternal depression, household food insecurity, and psychosocial stimulation. Children's anthropometry, venous hemoglobin and ferritin concentrations, and inflammation were also measured. Linear regression analyses were conducted to identify the concurrent and lagged biopsychosocial conditions associated with EEG-based brain activity. Growth, nutritional status, psychosocial stimulation, and household food security were associated with concurrent and lagged brain activity. The direction of association differed by EEG frequency band, but the majority of biopsychosocial conditions were positively associated with activity in the higher frequency bands and negatively with lower frequency bands. Our findings indicate that brain activity in children can be influenced by a range of biopsychosocial adversities. Children's nutrition, quality and quantity of psychosocial stimulation, and food security influence their current and later brain activity in this resource-limited setting in South Asia.</p>\n </section>\n \n <section>\n \n <h3> Trial Registration</h3>\n \n <p>ACTRN12617000660381</p>\n </section>\n </div>","PeriodicalId":47895,"journal":{"name":"Infancy","volume":"31 4","pages":""},"PeriodicalIF":2.4000,"publicationDate":"2026-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/infa.70108","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infancy","FirstCategoryId":"102","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/infa.70108","RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PSYCHOLOGY, DEVELOPMENTAL","Score":null,"Total":0}

引用次数: 0

Abstract

Adversities in early life compromise children's nurturing care and impact their development. This study explored the biopsychosocial conditions associated with electroencephalography (EEG)-based brain activity in children living in rural Bangladesh, a setting with high rates of malnutrition and suboptimal psychosocial stimulation. In a substudy of the Benefits and Risks of Iron Supplementation in Children (BRISC) study in Bangladesh, we recorded resting EEG brain activity in a random subsample of 440 children at 11 months and 594 children at 20 months of age. EEG band power measures were derived for delta, theta, alpha, and beta power bands. Validated tools were used to assess maternal depression, household food insecurity, and psychosocial stimulation. Children's anthropometry, venous hemoglobin and ferritin concentrations, and inflammation were also measured. Linear regression analyses were conducted to identify the concurrent and lagged biopsychosocial conditions associated with EEG-based brain activity. Growth, nutritional status, psychosocial stimulation, and household food security were associated with concurrent and lagged brain activity. The direction of association differed by EEG frequency band, but the majority of biopsychosocial conditions were positively associated with activity in the higher frequency bands and negatively with lower frequency bands. Our findings indicate that brain activity in children can be influenced by a range of biopsychosocial adversities. Children's nutrition, quality and quantity of psychosocial stimulation, and food security influence their current and later brain activity in this resource-limited setting in South Asia.

Trial Registration

ACTRN12617000660381

Abstract Image

查看原文本刊更多论文

孟加拉国幼儿的大脑活动与个人、家庭和家庭层面的生物心理社会状况有关

早期生活中的逆境会影响儿童的养育和发展。本研究探讨了与基于脑电图（EEG）的大脑活动相关的生物心理社会状况，这些儿童生活在孟加拉国农村，这是一个营养不良率高、心理社会刺激欠佳的环境。在孟加拉国儿童补铁的益处和风险（BRISC）研究的一个子研究中，我们记录了440名11个月大的儿童和594名20个月大的儿童的随机子样本的静息脑电图脑活动。推导了δ、θ、α和β功率波段的EEG波段功率测量。使用经过验证的工具来评估产妇抑郁症、家庭粮食不安全和社会心理刺激。同时测量儿童的人体测量、静脉血红蛋白和铁蛋白浓度以及炎症反应。进行线性回归分析，以确定与基于脑电图的大脑活动相关的同时和滞后的生物心理社会条件。生长、营养状况、社会心理刺激和家庭食品安全与并发和滞后的大脑活动有关。脑电图频带的相关方向不同，但大多数生物社会心理条件与活动在高频带呈正相关，在低频带呈负相关。我们的研究结果表明，儿童的大脑活动可能受到一系列生物、心理和社会逆境的影响。在南亚这个资源有限的环境中，儿童的营养、心理社会刺激的质量和数量以及粮食安全影响着他们当前和以后的大脑活动。试验注册ACTRN12617000660381

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Infancy PSYCHOLOGY, DEVELOPMENTAL-

CiteScore

4.00

自引率

7.70%

发文量

期刊介绍： Infancy, the official journal of the International Society on Infant Studies, emphasizes the highest quality original research on normal and aberrant infant development during the first two years. Both human and animal research are included. In addition to regular length research articles and brief reports (3000-word maximum), the journal includes solicited target articles along with a series of commentaries; debates, in which different theoretical positions are presented along with a series of commentaries; and thematic collections, a group of three to five reports or summaries of research on the same issue, conducted independently at different laboratories, with invited commentaries.