Key determinants of self-management in patients with non-dialysis-dependent chronic kidney disease: a systematic review.

IF 5.2 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

PUBLIC HEALTH REVIEWS Pub Date : 2026-06-30 eCollection Date: 2026-01-01 DOI:10.3389/phrs.2026.1609108

Alimzhan Muxunov, Dina Kalinina, Ikechi Okpechi, Racquel Lowe-Jones, Abduzhappar Gaipov, Zhanat Kuanshaliyeva, Symbat Bayakhmetova, Meruyert Madikenova, Antonio Sarria-Santamera

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Abstract

Objectives: Adoption of recommended self-management behaviors has been associated with a lower risk of disease progression, cardiovascular morbidity, and mortality in patients with chronic kidney disease (CKD). This systematic review aims to identify factors associated with the adherence of non-dialysis-dependent CKD (NDD-CKD) patients to recommended self-management practices.

Methods: Following PRISMA guidelines, we searched PubMed, Embase, Scopus, Medline, and CINAHL Plus databases from 1st January 2010 to 30th June 2024. The extracted data included associations of variables with self-management scores. The findings were descriptively presented in a grouped tabular form. The study was registered with the PROSPERO, CRD42024547304.

Results: From 1,914 studies identified, 16 cross-sectional studies with 3,658 participants were selected for inclusion. Objective CKD knowledge, health literacy, self-efficacy and social support consistently showed positive associations with self-management across multiple studies.

Conclusion: This systematic review revealed multiple factors associated with self-management in NDD-CKD patients, with disease-related knowledge, health literacy, and self-efficacy showing the most consistent positive associations across studies. Healthcare providers and policymakers should develop and implement health literacy and awareness programs as a strategy for improving patient outcomes.

Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=547304, identifier CRD42024547304.

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非透析依赖型慢性肾脏疾病患者自我管理的关键决定因素：系统综述

目的：采用推荐的自我管理行为与慢性肾脏疾病（CKD）患者疾病进展、心血管发病率和死亡率降低相关。本系统综述旨在确定与非透析依赖性CKD （NDD-CKD）患者遵守推荐的自我管理实践相关的因素。方法：按照PRISMA指南，检索PubMed、Embase、Scopus、Medline和CINAHL Plus数据库，检索时间为2010年1月1日至2024年6月30日。提取的数据包括变量与自我管理得分的关联。结果以分组表格形式描述性地呈现。该研究已在PROSPERO注册，编号为CRD42024547304。结果：从确定的1914项研究中，选择了16项横断面研究，共3,658名参与者纳入。目的在多项研究中，慢性肾病知识、健康素养、自我效能感和社会支持均与自我管理呈正相关。结论：本系统综述揭示了与NDD-CKD患者自我管理相关的多个因素，其中疾病相关知识、健康素养和自我效能感在各研究中表现出最一致的正相关。卫生保健提供者和决策者应制定和实施卫生素养和意识规划，作为改善患者预后的一项战略。系统评审注册：https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=547304，标识符CRD42024547304。

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