Cord blood lead screening in Lebanon: findings from the environmental exposures in Lebanese infants (EELI) study.

IF 4 4区 环境科学与生态学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY
Emile Whaibeh, Bassam Eid, Jowy Abi Hanna, Norma Aouad, Joyce Haddad, Georges Abi Tayeh, Myriam Mrad
{"title":"Cord blood lead screening in Lebanon: findings from the environmental exposures in Lebanese infants (EELI) study.","authors":"Emile Whaibeh, Bassam Eid, Jowy Abi Hanna, Norma Aouad, Joyce Haddad, Georges Abi Tayeh, Myriam Mrad","doi":"10.1080/26395940.2025.2524084","DOIUrl":null,"url":null,"abstract":"<p><p>This study aims to assess cord blood levels among pregnant women in Lebanon as part of the EELI study. Seventy-five umbilical cord blood samples collected from 2021 to 2022 were analyzed for lead content. Bivariate and multivariate tests were conducted to explore associations and identify predictors of elevated lead levels. The median lead concentration in cord blood was 0.545 μg/dL (range: 0.238 - 5.44 μg/dL). Higher maternal pre-pregnancy BMI and active smoking during pregnancy were associated with elevated lead levels (OR = 2.94, <i>p</i> = 0.005; OR = 14.94, <i>p</i> = 0.035). Surprisingly, proximity to construction sites was associated with lower lead levels (OR = 0.13, <i>p</i> = 0.037), possibly due to safer, modern infrastructure in newly developed areas with reduced legacy contamination. The findings indicate the need for continuous monitoring and public health interventions. While the sample size limits the generalizability of the findings, this pilot study offers important preliminary insights and underscores the need for large-scale screening, and awareness-raising campaigns.</p>","PeriodicalId":11785,"journal":{"name":"Environmental Pollutants and Bioavailability","volume":"37 1","pages":""},"PeriodicalIF":4.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13356099/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Environmental Pollutants and Bioavailability","FirstCategoryId":"93","ListUrlMain":"https://doi.org/10.1080/26395940.2025.2524084","RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/10 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

This study aims to assess cord blood levels among pregnant women in Lebanon as part of the EELI study. Seventy-five umbilical cord blood samples collected from 2021 to 2022 were analyzed for lead content. Bivariate and multivariate tests were conducted to explore associations and identify predictors of elevated lead levels. The median lead concentration in cord blood was 0.545 μg/dL (range: 0.238 - 5.44 μg/dL). Higher maternal pre-pregnancy BMI and active smoking during pregnancy were associated with elevated lead levels (OR = 2.94, p = 0.005; OR = 14.94, p = 0.035). Surprisingly, proximity to construction sites was associated with lower lead levels (OR = 0.13, p = 0.037), possibly due to safer, modern infrastructure in newly developed areas with reduced legacy contamination. The findings indicate the need for continuous monitoring and public health interventions. While the sample size limits the generalizability of the findings, this pilot study offers important preliminary insights and underscores the need for large-scale screening, and awareness-raising campaigns.

黎巴嫩脐带血铅筛查:黎巴嫩婴儿环境暴露研究结果。
本研究旨在评估黎巴嫩孕妇脐带血水平,作为EELI研究的一部分。对2021年至2022年收集的75份脐带血样本进行了铅含量分析。进行了双变量和多变量测试,以探讨相关性并确定铅水平升高的预测因素。脐带血中位铅浓度为0.545 μg/dL(范围0.238 ~ 5.44 μg/dL)。孕妇孕前BMI和孕期主动吸烟与铅水平升高相关(OR = 2.94, p = 0.005; OR = 14.94, p = 0.035)。令人惊讶的是,靠近建筑工地与较低的铅含量有关(OR = 0.13, p = 0.037),这可能是由于新开发地区的基础设施更安全,现代化,遗留污染减少。调查结果表明,需要持续监测和公共卫生干预措施。虽然样本量限制了研究结果的普遍性,但这项试点研究提供了重要的初步见解,并强调了大规模筛查和提高认识运动的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Environmental Pollutants and Bioavailability
Environmental Pollutants and Bioavailability Chemical Engineering-Chemical Health and Safety
CiteScore
4.30
自引率
3.00%
发文量
47
审稿时长
13 weeks
期刊介绍: Environmental Pollutants & Bioavailability is a peer-reviewed open access forum for insights on the chemical aspects of pollutants in the environment and biota, and their impacts on the uptake of the substances by living organisms. Topics include the occurrence, distribution, transport, transformation, transfer, fate, and effects of environmental pollutants, as well as their impact on living organisms. Substances of interests include heavy metals, persistent organic pollutants, and emerging contaminants, such as engineered nanomaterials, as well as pharmaceuticals and personal-care products as pollutants.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书