Synthesis and Structural Characterization of Gastric Mucosal Protective Agent Nano-Sucralfate

Abstract

In this experiment, nano-sucralfate for gastric mucosa protection was prepared by the pyridine method using sucrose, sulfuric acid and aluminum powder as raw materials. The product was characterized by Fourier transform infrared spectrometer (FTIR), thermogravimetric analyzer (TGA) and its surface micro-morphology was observed by scanning electron microscope (SEM).. Infrared spectroscopy and thermogravimetric analysis explored the physical and chemical properties of sucralfate, providing specific data support for its practical application. SEM images showed that sucralfate particles had a porous flower-like structure with high porosity. In addition, the synthesized product has high purity and good thermal stability, which play an important role in improving its protective effect on gastric mucosa.