Oral cavity cancer: retrospective analysis of a tertiary level hospital.

Cirugia y cirujanos Pub Date : 2026-07-03 DOI:10.24875/CIRU.25000099

Hector Gurrola-Machuca, Gabriela Nuñez-Guardado, Patricia E Sánchez-Valencia, Hector Gurrola-Luna, Eduardo Cardenas-Cardenas

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Abstract

Objective: To describe the clinical characteristics, treatment patterns, and survival outcomes of patients with oral cavity cancer treated at a tertiary care center.

Methods: A retrospective study was conducted on 224 patients with oral cavity cancer treated between 1988 and 2023. Clinical, pathological, and therapeutic data were collected, evaluating survival through Kaplan-Meier curves and Cox regression models.

Results: The median overall survival was 92.3 months, with a better prognosis in early stages (111.6 months in stage I) and in patients treated surgically. Non-SCC tumors showed significantly greater survival. The use of induction chemotherapy followed by radiotherapy notably improved survival in advanced disease (203.9 months). Surgery was confirmed as the most effective strategy in the early stages.

Conclusions: Age, functional status, histology, and clinical stage at diagnosis are relevant prognostic factors. Surgery remains the cornerstone of treatment, and in locally advanced disease, induction chemotherapy is an option.

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某三级医院口腔癌的回顾性分析。

目的：描述在三级保健中心接受治疗的口腔癌患者的临床特征、治疗模式和生存结局。方法：对1988 ~ 2023年间224例口腔癌患者的临床资料进行回顾性分析。收集临床、病理和治疗数据，通过Kaplan-Meier曲线和Cox回归模型评估生存率。结果：中位总生存期为92.3个月，早期（I期111.6个月）和手术治疗患者预后较好。非鳞状细胞癌肿瘤的生存率明显更高。采用诱导化疗后放疗可显著提高晚期疾病患者的生存期（203.9个月）。手术在早期被证实是最有效的策略。结论：年龄、功能状态、组织学和诊断时的临床分期是影响预后的相关因素。手术仍然是治疗的基础，在局部晚期疾病中，诱导化疗是一种选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Cirugia y cirujanos

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