Alessandro Affronti, Francesco Loreni, Federico Fortuni, Claudia Castellani, Marcello Bergonzini
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引用次数: 0
Abstract
A 73-year-old male developed early prosthetic aortic valve endocarditis complicated by haemorrhagic cerebral lesions 45 days after tissue valve replacement. Transesophageal echocardiography revealed bulky vegetations and an annular abscess. Urgent surgical valve replacement with extensive debridement was performed, while broad-spectrum antifungal therapy was initiated. Aspergillus terreus was subsequently confirmed. Postoperatively, the patient experienced acute hydrocephalus, subarachnoid haemorrhage, and recurrent vegetations, ultimately precluding further surgery. He died on postoperative day 57. This case highlights the diagnostic and therapeutic challenges of early fungal prosthetic endocarditis with intracranial haemorrhage, emphasizing individualized management by multidisciplinary teams and the high mortality associated with Aspergillus infections.
期刊介绍：
The Asian Cardiovascular and Thoracic Annals is an international peer-reviewed journal pertaining to cardiovascular and thoracic medicine. Besides original clinical manuscripts, we welcome research reports, product reviews, reports of new techniques, and findings of special significance to Asia and the Pacific Rim. Case studies that have significant novel original observations, are instructive, include adequate methodological details and provide conclusions. Workshop proceedings, meetings and book reviews, letters to the editor, and meeting announcements are encouraged along with relevant articles from authors.
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