{"title":"Synteny Analysis and Visualization of Gene Clusters.","authors":"Chanchan Liu, Dishuai Li, Qinan Wu","doi":"10.1007/978-1-0716-5384-5_6","DOIUrl":null,"url":null,"abstract":"<p><p>As the cost of genome sequencing continues to decline, an increasing number of plant genomes are being sequenced and assembled. This progress allows for the comparison of synteny and microsynteny among genomes and gene clusters across various species, facilitating the exploration of their evolutionary relationships.In this chapter, we describe current methods for analyzing collinearity and synteny among multiple genomes using existing tools from JCVI. We also present a detailed case study that illustrates these methods, utilizing data from four plant genome datasets.</p>","PeriodicalId":18490,"journal":{"name":"Methods in molecular biology","volume":"3054 ","pages":"77-87"},"PeriodicalIF":0.0000,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Methods in molecular biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/978-1-0716-5384-5_6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Biochemistry, Genetics and Molecular Biology","Score":null,"Total":0}
引用次数: 0
Abstract
As the cost of genome sequencing continues to decline, an increasing number of plant genomes are being sequenced and assembled. This progress allows for the comparison of synteny and microsynteny among genomes and gene clusters across various species, facilitating the exploration of their evolutionary relationships.In this chapter, we describe current methods for analyzing collinearity and synteny among multiple genomes using existing tools from JCVI. We also present a detailed case study that illustrates these methods, utilizing data from four plant genome datasets.
期刊介绍:
For over 20 years, biological scientists have come to rely on the research protocols and methodologies in the critically acclaimed Methods in Molecular Biology series. The series was the first to introduce the step-by-step protocols approach that has become the standard in all biomedical protocol publishing. Each protocol is provided in readily-reproducible step-by-step fashion, opening with an introductory overview, a list of the materials and reagents needed to complete the experiment, and followed by a detailed procedure that is supported with a helpful notes section offering tips and tricks of the trade as well as troubleshooting advice.