{"title":"[Out-of-hospital cardiac arrest : Current recommendations along the chain of survival and patient management].","authors":"Markus Bork, J-S Pooth, G Michels, H-J Busch","doi":"10.1007/s00063-026-01462-1","DOIUrl":null,"url":null,"abstract":"<p><p>Out-of-hospital cardiac arrest (OHCA) continues to pose a significant clinical challenge with low survival rates. The updated 2025 guidelines emphasize the critical role of the chain of survival, optimized basic life support (BLS) and the strategic use of extracorporeal cardiopulmonary resuscitation (ECPR). Following the return of spontaneous circulation (ROSC) the clinical course is predominantly shaped by the post-cardiac arrest syndrome (PCAS). Structured care within specialized centers and a multimodal timely neuroprognostication are essential to improve neurological outcomes and facilitate evidence-based decision-making regarding further treatment.</p>","PeriodicalId":49019,"journal":{"name":"Medizinische Klinik-Intensivmedizin Und Notfallmedizin","volume":" ","pages":"594-605"},"PeriodicalIF":1.6000,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medizinische Klinik-Intensivmedizin Und Notfallmedizin","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00063-026-01462-1","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/6/23 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Out-of-hospital cardiac arrest (OHCA) continues to pose a significant clinical challenge with low survival rates. The updated 2025 guidelines emphasize the critical role of the chain of survival, optimized basic life support (BLS) and the strategic use of extracorporeal cardiopulmonary resuscitation (ECPR). Following the return of spontaneous circulation (ROSC) the clinical course is predominantly shaped by the post-cardiac arrest syndrome (PCAS). Structured care within specialized centers and a multimodal timely neuroprognostication are essential to improve neurological outcomes and facilitate evidence-based decision-making regarding further treatment.
期刊介绍:
Medizinische Klinik – Intensivmedizin und Notfallmedizin is an internationally respected interdisciplinary journal. It is intended for physicians, nurses, respiratory and physical therapists active in intensive care and accident/emergency units, but also for internists, anesthesiologists, surgeons, neurologists, and pediatricians with special interest in intensive care medicine.
Comprehensive reviews describe the most recent advances in the field of internal medicine with special focus on intensive care problems. Freely submitted original articles present important studies in this discipline and promote scientific exchange, while articles in the category Photo essay feature interesting cases and aim at optimizing diagnostic and therapeutic strategies. In the rubric journal club well-respected experts comment on outstanding international publications. Review articles under the rubric "Continuing Medical Education" present verified results of scientific research and their integration into daily practice. The rubrics "Nursing practice" and "Physical therapy" round out the information.