2058-P: Integrating Sleep Health into Cardiometabolic Care

IF 9.3 1区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Diabetes Pub Date : 2026-06-11 DOI:10.2337/db26-2058-p
NAZLI PARAST, JAMES KIM, AKSHAY JAIN, W. JEROME ALONSO
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引用次数: 0

Abstract

Introduction and Objective: Background: Insomnia is highly prevalent and contributes to cardiometabolic disease through adverse effects on glucose metabolism, insulin resistance, sympathetic activation, cortisol elevation, and inflammation. These mechanisms are increasingly recognized as clinically relevant to diabetes risk and glycemic instability. Despite this, sleep disturbances remain underassessed in diabetes and obesity care. Methods: A two-phase study was conducted. Phase 1 assessed sleep concerns in patients with diabetes and/or obesity attending specialist endocrine/metabolic clinics. Sixty-nine participants completed structured assessments evaluating sleep satisfaction, insomnia symptoms, and functional impact. Phase 2 focused on knowledge translation to primary care networks, including dissemination of findings and provision of educational materials to support insomnia screening and management. Results: Only 46% of patients reported prior sleep assessment by their primary care provider. Twenty-three percent preferred discussing sleep concerns with their provider, and 9% required and agreed to pharmacologic treatment. Approximately 70% stated that being asked about sleep increased their understanding of its importance for metabolic and glycemic health. Most participants were satisfied or very satisfied with sleep assessment in the specialist setting. Conclusion: Insomnia is prevalent, underassessed, and clinically meaningful in patients with diabetes and obesity. The physiologic effects of insomnia—including increased insulin resistance and impaired glucose metabolism—underscore its importance as a modifiable component of cardiometabolic care. Feasibility data from specialty clinics and positive patient engagement support integrating structured sleep assessment into routine practice. Knowledge translation to primary care providers may enhance early identification and management of insomnia, with potential benefits for glycemic outcomes and overall cardiometabolic risk reduction. Disclosure N. Parast: None. J. Kim: Advisory Panel; Current; Abbott Diabetes. Speaker's Bureau; Current; Abbott Diabetes. Advisory Panel; Current; AbbVie Inc. Speaker's Bureau; Current; AbbVie Inc. Research Support; Current; AbbVie Inc. Speaker's Bureau; Current; Bayer AG. Advisory Panel; Current; Bayer AG. Research Support; Current; Bayer AG. Advisory Panel; Current; Boehringer Ingelheim International GmbH. Speaker's Bureau; Current; Boehringer Ingelheim International GmbH. Advisory Panel; Current; Eisai Inc. Speaker's Bureau; Current; Eisai Inc. Research Support; Current; Eisai Inc. Advisory Panel; Current; Eli Lilly and Company, embecta. Speaker's Bureau; Current; embecta. Advisory Panel; Current; GlaxoSmithKline plc. Speaker's Bureau; Current; GlaxoSmithKline plc. Advisory Panel; Current; Lundbeck. Speaker's Bureau; Current; Lundbeck. Research Support; Current; Idorsia Pharmaceuticals Ltd. Advisory Panel; Current; Novo Nordisk Canada Inc. Speaker's Bureau; Current; Novo Nordisk Canada Inc., Otsuka Pharmaceutical Co., Ltd. Research Support; Current; Idorsia Pharmaceuticals Ltd. Speaker's Bureau; Current; Pfizer Inc. Advisory Panel; Current; Pfizer Inc. Speaker's Bureau; Current; Searchlight Pharmaceuticals, Takeda Canada. Advisory Panel; Current; Takeda Canada, Teva Pharmaceutical Industries Ltd., Sanofi. Speaker's Bureau; Current; Sanofi. A. Jain: Other - Advisory panel, speaker's bureau, research support; Current; Abbott, Eli Lilly and Company, Novo Nordisk, Sanofi. Research Support; Current; AstraZeneca. Other - Advisory panel, speaker's bureau; Current; Dexcom, Inc., Eisai Co., Ltd., embecta. Research Support; Current; Roche Canada. Advisory Panel; Current; Boehringer Ingelheim International GmbH. W. Alonso: Speaker's Bureau; Ended; Eisai Inc., Eli Lilly and Company. Advisory Panel; Current; Idorsia Pharmaceuticals Ltd. Research Support; Current; Eli Lilly and Company.
2058-P:将睡眠健康纳入心脏代谢护理
简介和目的:背景:失眠是非常普遍的,并且通过对葡萄糖代谢、胰岛素抵抗、交感神经激活、皮质醇升高和炎症的不良影响而导致心脏代谢疾病。这些机制在临床上越来越被认为与糖尿病风险和血糖不稳定有关。尽管如此,睡眠障碍在糖尿病和肥胖症治疗中仍然被低估。方法:采用两期研究。第一阶段评估了在内分泌/代谢专科诊所就诊的糖尿病和/或肥胖患者的睡眠问题。69名参与者完成了结构化的评估,评估睡眠满意度、失眠症状和功能影响。第二阶段的重点是将知识转化为初级保健网络,包括传播研究结果和提供教育材料,以支持失眠筛查和管理。结果:只有46%的患者报告了他们的初级保健提供者先前的睡眠评估。23%的人更愿意与医生讨论睡眠问题,9%的人要求并同意药物治疗。大约70%的人表示,被问及睡眠问题使他们更加了解睡眠对新陈代谢和血糖健康的重要性。大多数参与者对专家设置的睡眠评估感到满意或非常满意。结论:失眠在糖尿病和肥胖患者中普遍存在,但被低估,且具有临床意义。失眠的生理效应——包括胰岛素抵抗的增加和葡萄糖代谢的受损——强调了它作为心脏代谢护理的可改变成分的重要性。来自专业诊所的可行性数据和积极的患者参与支持将结构化睡眠评估纳入日常实践。对初级保健提供者的知识转化可能会加强失眠的早期识别和管理,对血糖结局和整体心脏代谢风险降低有潜在的好处。N.帕拉斯特:没有。J. Kim:咨询小组;当前的;雅培糖尿病。演讲者的局;当前的;雅培糖尿病。顾问小组;当前的;AbbVie Inc .)演讲者的局;当前的;AbbVie Inc .)研究支持;当前的;AbbVie Inc .)演讲者的局;当前的;拜耳公司。顾问小组;当前的;拜耳公司。研究支持;当前的;拜耳公司。顾问小组;当前的;勃林格殷格翰国际有限公司演讲者的局;当前的;勃林格殷格翰国际有限公司顾问小组;当前的;卫材公司。演讲者的局;当前的;卫材公司。研究支持;当前的;卫材公司。顾问小组;当前的;礼来公司,谢谢。演讲者的局;当前的;embecta。顾问小组;当前的;葛兰素史克。演讲者的局;当前的;葛兰素史克。顾问小组;当前的;Lundbeck公司。它是一家演讲者的局;当前的;Lundbeck公司。它是一家研究支持;当前的;Idorsia制药有限公司顾问小组;当前的;诺和诺德加拿大公司演讲者的局;当前的;诺和诺德加拿大公司、大冢制药株式会社研究支持;当前的;Idorsia制药有限公司演讲者的局;当前的;辉瑞公司顾问小组;当前的;辉瑞公司演讲者的局;当前的;加拿大武田探照灯制药公司。顾问小组;当前的;武田加拿大,梯瓦制药,赛诺菲。演讲者的局;当前的;赛诺菲。A. Jain:其他-顾问团,发言人局,研究支持;当前的;雅培,礼来公司,诺和诺德,赛诺菲。研究支持;当前的;阿斯利康。其他-顾问团、发言人局;当前的;Dexcom, Inc., Eisai Co., Ltd., embecta。研究支持;当前的;罗氏加拿大。顾问小组;当前的;勃林格殷格翰国际有限公司W.阿隆索:发言人办公室;结束;卫材公司,礼来公司。顾问小组;当前的;Idorsia制药有限公司研究支持;当前的;礼来公司。
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来源期刊
Diabetes
Diabetes 医学-内分泌学与代谢
CiteScore
12.50
自引率
2.60%
发文量
1968
审稿时长
1 months
期刊介绍: Diabetes is a scientific journal that publishes original research exploring the physiological and pathophysiological aspects of diabetes mellitus. We encourage submissions of manuscripts pertaining to laboratory, animal, or human research, covering a wide range of topics. Our primary focus is on investigative reports investigating various aspects such as the development and progression of diabetes, along with its associated complications. We also welcome studies delving into normal and pathological pancreatic islet function and intermediary metabolism, as well as exploring the mechanisms of drug and hormone action from a pharmacological perspective. Additionally, we encourage submissions that delve into the biochemical and molecular aspects of both normal and abnormal biological processes. However, it is important to note that we do not publish studies relating to diabetes education or the application of accepted therapeutic and diagnostic approaches to patients with diabetes mellitus. Our aim is to provide a platform for research that contributes to advancing our understanding of the underlying mechanisms and processes of diabetes.
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