NAZLI PARAST, JAMES KIM, AKSHAY JAIN, W. JEROME ALONSO
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引用次数: 0
Abstract
Introduction and Objective: Background: Insomnia is highly prevalent and contributes to cardiometabolic disease through adverse effects on glucose metabolism, insulin resistance, sympathetic activation, cortisol elevation, and inflammation. These mechanisms are increasingly recognized as clinically relevant to diabetes risk and glycemic instability. Despite this, sleep disturbances remain underassessed in diabetes and obesity care. Methods: A two-phase study was conducted. Phase 1 assessed sleep concerns in patients with diabetes and/or obesity attending specialist endocrine/metabolic clinics. Sixty-nine participants completed structured assessments evaluating sleep satisfaction, insomnia symptoms, and functional impact. Phase 2 focused on knowledge translation to primary care networks, including dissemination of findings and provision of educational materials to support insomnia screening and management. Results: Only 46% of patients reported prior sleep assessment by their primary care provider. Twenty-three percent preferred discussing sleep concerns with their provider, and 9% required and agreed to pharmacologic treatment. Approximately 70% stated that being asked about sleep increased their understanding of its importance for metabolic and glycemic health. Most participants were satisfied or very satisfied with sleep assessment in the specialist setting. Conclusion: Insomnia is prevalent, underassessed, and clinically meaningful in patients with diabetes and obesity. The physiologic effects of insomnia—including increased insulin resistance and impaired glucose metabolism—underscore its importance as a modifiable component of cardiometabolic care. Feasibility data from specialty clinics and positive patient engagement support integrating structured sleep assessment into routine practice. Knowledge translation to primary care providers may enhance early identification and management of insomnia, with potential benefits for glycemic outcomes and overall cardiometabolic risk reduction. Disclosure N. Parast: None. J. Kim: Advisory Panel; Current; Abbott Diabetes. Speaker's Bureau; Current; Abbott Diabetes. Advisory Panel; Current; AbbVie Inc. Speaker's Bureau; Current; AbbVie Inc. Research Support; Current; AbbVie Inc. Speaker's Bureau; Current; Bayer AG. Advisory Panel; Current; Bayer AG. Research Support; Current; Bayer AG. Advisory Panel; Current; Boehringer Ingelheim International GmbH. Speaker's Bureau; Current; Boehringer Ingelheim International GmbH. Advisory Panel; Current; Eisai Inc. Speaker's Bureau; Current; Eisai Inc. Research Support; Current; Eisai Inc. Advisory Panel; Current; Eli Lilly and Company, embecta. Speaker's Bureau; Current; embecta. Advisory Panel; Current; GlaxoSmithKline plc. Speaker's Bureau; Current; GlaxoSmithKline plc. Advisory Panel; Current; Lundbeck. Speaker's Bureau; Current; Lundbeck. Research Support; Current; Idorsia Pharmaceuticals Ltd. Advisory Panel; Current; Novo Nordisk Canada Inc. Speaker's Bureau; Current; Novo Nordisk Canada Inc., Otsuka Pharmaceutical Co., Ltd. Research Support; Current; Idorsia Pharmaceuticals Ltd. Speaker's Bureau; Current; Pfizer Inc. Advisory Panel; Current; Pfizer Inc. Speaker's Bureau; Current; Searchlight Pharmaceuticals, Takeda Canada. Advisory Panel; Current; Takeda Canada, Teva Pharmaceutical Industries Ltd., Sanofi. Speaker's Bureau; Current; Sanofi. A. Jain: Other - Advisory panel, speaker's bureau, research support; Current; Abbott, Eli Lilly and Company, Novo Nordisk, Sanofi. Research Support; Current; AstraZeneca. Other - Advisory panel, speaker's bureau; Current; Dexcom, Inc., Eisai Co., Ltd., embecta. Research Support; Current; Roche Canada. Advisory Panel; Current; Boehringer Ingelheim International GmbH. W. Alonso: Speaker's Bureau; Ended; Eisai Inc., Eli Lilly and Company. Advisory Panel; Current; Idorsia Pharmaceuticals Ltd. Research Support; Current; Eli Lilly and Company.
期刊介绍:
Diabetes is a scientific journal that publishes original research exploring the physiological and pathophysiological aspects of diabetes mellitus. We encourage submissions of manuscripts pertaining to laboratory, animal, or human research, covering a wide range of topics. Our primary focus is on investigative reports investigating various aspects such as the development and progression of diabetes, along with its associated complications. We also welcome studies delving into normal and pathological pancreatic islet function and intermediary metabolism, as well as exploring the mechanisms of drug and hormone action from a pharmacological perspective. Additionally, we encourage submissions that delve into the biochemical and molecular aspects of both normal and abnormal biological processes.
However, it is important to note that we do not publish studies relating to diabetes education or the application of accepted therapeutic and diagnostic approaches to patients with diabetes mellitus. Our aim is to provide a platform for research that contributes to advancing our understanding of the underlying mechanisms and processes of diabetes.