{"title":"Logit Fingerprinting: A Novel, Accuracy-Independent Method for Validating Large Language Model Stability in High-Stakes Clinical Applications.","authors":"W Vaiden Logan, V K Cody Bumgardner","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The integration of Large Language Models (LLMs) into clinical settings requires quality assurance mechanisms capable of detecting the hidden effects of model compression and architectural instability. Conventional accuracy metrics often fail to capture the behavioral volatility introduced by quantization, distillation, and sparse architectures. We propose the \"Single-Token Forced-Choice Logit Probe,\" a method that generates a \"behavioral fingerprint\" of a model by analyzing its decision-making stability on a domain-specific (MedQA) benchmark. Validated on 11 local model families, our approach achieved 100% accuracy in distinguishing full-precision models from quantized variants. Furthermore, a longitudinal audit of commercial APIs revealed a distinct \"Stability Gap\": distilled \"Nano\" models exhibited nearly double the decision instability (2.82% vs. 1.58% Flip Rate) of their standard counterparts. Forensic classification identified the underlying compression techniques (Q8 vs. FP8), while analysis suggests the inherent non-determinism stems from Sparse Mixture-of-Experts (SMoE) routing. We conclude that Flip Rate is a critical safety metric and that distilled and quantized models require rigorous stability auditing before clinical deployment.</p>","PeriodicalId":72181,"journal":{"name":"AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science","volume":"2026 ","pages":"287-292"},"PeriodicalIF":0.0000,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13274300/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The integration of Large Language Models (LLMs) into clinical settings requires quality assurance mechanisms capable of detecting the hidden effects of model compression and architectural instability. Conventional accuracy metrics often fail to capture the behavioral volatility introduced by quantization, distillation, and sparse architectures. We propose the "Single-Token Forced-Choice Logit Probe," a method that generates a "behavioral fingerprint" of a model by analyzing its decision-making stability on a domain-specific (MedQA) benchmark. Validated on 11 local model families, our approach achieved 100% accuracy in distinguishing full-precision models from quantized variants. Furthermore, a longitudinal audit of commercial APIs revealed a distinct "Stability Gap": distilled "Nano" models exhibited nearly double the decision instability (2.82% vs. 1.58% Flip Rate) of their standard counterparts. Forensic classification identified the underlying compression techniques (Q8 vs. FP8), while analysis suggests the inherent non-determinism stems from Sparse Mixture-of-Experts (SMoE) routing. We conclude that Flip Rate is a critical safety metric and that distilled and quantized models require rigorous stability auditing before clinical deployment.
将大型语言模型(llm)集成到临床环境中需要能够检测模型压缩和架构不稳定性的隐藏影响的质量保证机制。传统的精度度量常常不能捕获由量化、蒸馏和稀疏架构引入的行为波动。我们提出了“单令牌强制选择Logit探针”,这是一种通过分析特定领域(MedQA)基准上的决策稳定性来生成模型“行为指纹”的方法。在11个局部模型族上进行了验证,我们的方法在区分全精度模型和量化变量方面达到了100%的准确率。此外,对商业api的纵向审计显示出明显的“稳定性差距”:蒸馏的“Nano”模型表现出的决策不稳定性(2.82% vs. 1.58%翻转率)几乎是标准api的两倍。取证分类确定了底层压缩技术(Q8 vs. FP8),而分析表明,固有的不确定性源于稀疏混合专家(SMoE)路由。我们得出结论,翻转率是一个关键的安全指标,在临床部署之前,蒸馏和量化模型需要严格的稳定性审计。