Monochorionic triamniotic (MCTA) triplet pregnancy complicated by TRAP sequence: successful management with ultrasound-guided radiofrequency ablation and favourable outcome.

Chanchal Singh, Vrunda Appannagari, Naveen Gupta, Shreya Goel, N Mohit, Jayasree Sundar
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Abstract

We present a case of a 30-year-old G3P2L1 with a spontaneously conceived monochorionic triamniotic (MCTA) triplet pregnancy complicated by a Twin Reversed Arterial Perfusion (TRAP) sequence in one fetus. Early ultrasound at 10 weeks 4 days showed MCTA triplets with one hydropic fetus with alobar holoprosencephaly. A review scan at 12 weeks 6 days gestation showed that this fetus with holoprosencephaly had no heart. Colour Doppler showed a single artery in the acardiac fetus, suggestive of twin reverse arterial perfusion (TRAP sequence). Ultrasound-guided radiofrequency ablation (RFA) was successfully performed at 19 weeks and 2 days. The patient required cerclage at 23 weeks due to cervical shortening. She was delivered by Caesarean section at 33 weeks and 5 days in view of fetal growth restriction and abnormal Dopplers in twin 2. Both babies, weighing 1625g and 1460 g, were discharged well after 7 & 11 days of NICU stay. This case highlights the importance of early diagnosis, ultrasound surveillance, timely intervention, and multidisciplinary care in the management of this extremely rare triplet pregnancy.

单绒毛膜三羊膜(MCTA)三胞胎妊娠合并TRAP序列:超声引导射频消融术的成功管理和良好的结果。
我们提出了一例30岁的G3P2L1与自然受孕单绒毛膜三羊膜(MCTA)三胞胎妊娠合并双动脉灌注逆转(TRAP)序列在一个胎儿。妊娠10周第4天早期超声显示MCTA三胞胎,其中1例积水胎儿伴空叶前脑畸形。妊娠12周6天复查扫描显示,该胎儿前脑全畸形无心脏。彩色多普勒显示胎儿心脏有一条动脉,提示双动脉反向灌注(TRAP序列)。超声引导射频消融(RFA)在19周零2天成功实施。由于颈椎缩短,患者在23周时需要行环切术。因胎儿生长受限,双胎2号多普勒异常,于33周零5天剖腹分娩。新生儿体重分别为1625g和1460g,在新生儿重症监护室停留7天和11天后出院。本病例强调了早期诊断、超声监测、及时干预和多学科护理在这种极其罕见的三胞胎妊娠管理中的重要性。
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