Artificial Intelligence in Pelvic Fracture Diagnosis and Outcome Prediction: A Systematic Review and Meta-analysis

IF 5
Kevin J. Wang MS , Aazad Abbas MD , Geoffrey W. Schemitsch MD , Matthew Raleigh MD , Johnathan R. Lex MBChB , Hilary Felice MD , Markku Nousiainen MD , Cari Whyne PhD , Bheeshma Ravi MD , Robert Koucheki MD, MEng
{"title":"Artificial Intelligence in Pelvic Fracture Diagnosis and Outcome Prediction: A Systematic Review and Meta-analysis","authors":"Kevin J. Wang MS ,&nbsp;Aazad Abbas MD ,&nbsp;Geoffrey W. Schemitsch MD ,&nbsp;Matthew Raleigh MD ,&nbsp;Johnathan R. Lex MBChB ,&nbsp;Hilary Felice MD ,&nbsp;Markku Nousiainen MD ,&nbsp;Cari Whyne PhD ,&nbsp;Bheeshma Ravi MD ,&nbsp;Robert Koucheki MD, MEng","doi":"10.1016/j.mcpdig.2026.100367","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><div>To synthesize the performance of artificial intelligence (AI) applications for detecting pelvic fractures, classifying severity, and predicting clinical outcomes relative to clinicians.</div></div><div><h3>Patients and Methods</h3><div>The study was designed as a systematic review and meta-analysis (PROSPERO CRD420251141768). Ovid Embase, Ovid MEDLINE, PubMed, Scopus, and Cochrane CENTRAL were searched for articles published from database inception to September 11, 2025. Studies were included if they evaluated AI models for pelvic ring fractures in adults using pelvic radiographs. Case series, reviews, and abstracts without full data were excluded. Summary level data were independently extracted using a standardized template. Diagnostic metrics were pooled using a random-effects model. Outcomes included pooled sensitivity, specificity, area under the receiver operating characteristic curve (AUC), and accuracy.</div></div><div><h3>Results</h3><div>Fourteen studies were included. Thirteen studies evaluated radiographic fracture detection or classification (n=31,166 radiographs) and one study evaluated outcome prediction. AI demonstrated high pooled performance: accuracy 0.96 (95% CI, 0.91-0.98; <em>I</em><sup><em>2</em></sup>=93.3%), AUC 0.94 (95% CI, 0.89-0.97; <em>I</em><sup><em>2</em></sup>=97.9%), sensitivity 0.90 (95% CI, 0.84-0.94; <em>τ</em><sup>2</sup>=0.42), and specificity 0.93 (95% CI, 0.85-0.97; <em>τ</em><sup>2</sup>=1.30). In 3 studies directly comparing AI with clinicians, AI models showed comparable or marginally superior performance. One study on clinical outcomes reported strong performance for predicting hemodynamic instability (AUC 0.92) and mortality (AUC 0.90).</div></div><div><h3>Conclusion</h3><div>AI algorithms show promise as supportive tools for pelvic fracture detection, achieving diagnostic performance comparable to expert clinicians. However, included studies exhibit substantial heterogeneity, selection bias, and limited external validation. Large-scale, prospective validation is necessary before widespread clinical adoption.</div></div>","PeriodicalId":74127,"journal":{"name":"Mayo Clinic Proceedings. Digital health","volume":"4 2","pages":"Article 100367"},"PeriodicalIF":5.0000,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Mayo Clinic Proceedings. Digital health","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2949761226000337","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/4/25 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Objectives

To synthesize the performance of artificial intelligence (AI) applications for detecting pelvic fractures, classifying severity, and predicting clinical outcomes relative to clinicians.

Patients and Methods

The study was designed as a systematic review and meta-analysis (PROSPERO CRD420251141768). Ovid Embase, Ovid MEDLINE, PubMed, Scopus, and Cochrane CENTRAL were searched for articles published from database inception to September 11, 2025. Studies were included if they evaluated AI models for pelvic ring fractures in adults using pelvic radiographs. Case series, reviews, and abstracts without full data were excluded. Summary level data were independently extracted using a standardized template. Diagnostic metrics were pooled using a random-effects model. Outcomes included pooled sensitivity, specificity, area under the receiver operating characteristic curve (AUC), and accuracy.

Results

Fourteen studies were included. Thirteen studies evaluated radiographic fracture detection or classification (n=31,166 radiographs) and one study evaluated outcome prediction. AI demonstrated high pooled performance: accuracy 0.96 (95% CI, 0.91-0.98; I2=93.3%), AUC 0.94 (95% CI, 0.89-0.97; I2=97.9%), sensitivity 0.90 (95% CI, 0.84-0.94; τ2=0.42), and specificity 0.93 (95% CI, 0.85-0.97; τ2=1.30). In 3 studies directly comparing AI with clinicians, AI models showed comparable or marginally superior performance. One study on clinical outcomes reported strong performance for predicting hemodynamic instability (AUC 0.92) and mortality (AUC 0.90).

Conclusion

AI algorithms show promise as supportive tools for pelvic fracture detection, achieving diagnostic performance comparable to expert clinicians. However, included studies exhibit substantial heterogeneity, selection bias, and limited external validation. Large-scale, prospective validation is necessary before widespread clinical adoption.
人工智能在骨盆骨折诊断和预后预测中的应用:系统回顾和荟萃分析
目的综合人工智能(AI)在骨盆骨折检测、严重程度分类和临床预后预测方面的应用性能。患者和方法本研究设计为系统评价和荟萃分析(PROSPERO CRD420251141768)。检索了Ovid Embase、Ovid MEDLINE、PubMed、Scopus和Cochrane CENTRAL从数据库建立到2025年9月11日发表的文章。使用骨盆x线片评估人工智能模型治疗成人骨盆环骨折的研究被纳入。排除了没有完整数据的病例系列、综述和摘要。使用标准化模板独立提取汇总水平数据。采用随机效应模型汇总诊断指标。结果包括敏感性、特异性、受试者工作特征曲线下面积(AUC)和准确性。结果共纳入14项研究。13项研究评估了x线片骨折检测或分类(n=31,166张x线片),1项研究评估了结果预测。人工智能表现出很高的综合性能:准确率0.96 (95% CI, 0.91-0.98; I2=93.3%), AUC 0.94 (95% CI, 0.89-0.97; I2=97.9%),灵敏度0.90 (95% CI, 0.84-0.94; τ2=0.42),特异性0.93 (95% CI, 0.85-0.97; τ2=1.30)。在3项直接比较人工智能与临床医生的研究中,人工智能模型的表现相当或略优于临床医生。一项关于临床结果的研究报告了预测血流动力学不稳定性(AUC 0.92)和死亡率(AUC 0.90)的强大性能。结论人工智能算法有望成为骨盆骨折检测的辅助工具,其诊断性能可与临床专家相媲美。然而,纳入的研究显示出大量的异质性、选择偏倚和有限的外部验证。在广泛的临床应用之前,有必要进行大规模的前瞻性验证。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Mayo Clinic Proceedings. Digital health
Mayo Clinic Proceedings. Digital health Medicine and Dentistry (General), Health Informatics, Public Health and Health Policy
自引率
0.00%
发文量
0
审稿时长
47 days
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书