Systematic gastric surveillance in patients with familial adenomatous polyposis

Q3 Medicine

VideoGIE Pub Date : 2026-06-01 Epub Date: 2025-12-26 DOI:10.1016/j.vgie.2025.12.007

Hicham Bouchiba MD , Dewkoemar Ramsoekh MD, PhD , Arthur S. Aelvoet MD, PhD , Barbara A.J. Bastiaansen MD , Evelien Dekker MD, PhD

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Abstract

Background and Aims

Familial adenomatous polyposis (FAP) has shown a rising incidence of gastric cancer, particularly in the proximal stomach. We aimed to demonstrate a systematic protocol to improve gastric surveillance in FAP.

Methods

The protocol consists of systematic gastric examination using white-light endoscopy and narrow-band imaging combined with patient repositioning from the left lateral to supine position in cases with carpeting fundic gland polyposis.

Results

Three FAP cases illustrate the diagnostic value of this approach. In 2 cases, supine repositioning improved visualization of mucosa obscured by carpeting fundic gland polyps. In the third case, an ulcerated adenocarcinoma hidden among polyps with the patient in the left lateral position became visible only after repositioning.

Conclusions

Systematic gastric surveillance with advanced imaging and patient repositioning can reveal lesions not visible on standard inspection. This approach may enhance early detection of premalignant and malignant gastric lesions in FAP.

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家族性腺瘤性息肉病患者的系统胃监测

背景和目的家族性腺瘤性息肉病（FAP）已显示出胃癌的发病率上升，特别是在近端胃。我们的目的是展示一种系统的方案来改善FAP患者的胃监测。方法对地毯状基底腺息肉病患者行系统的白光内镜和窄带成像检查，并将患者从左侧侧卧位改为仰卧位。结果3例FAP病例说明了该方法的诊断价值。2例仰卧位可改善基底腺息肉掩盖粘膜的显像。第三例患者左侧卧位，溃疡性腺癌隐藏在息肉中，重新体位后才可见。结论系统的胃监测，采用先进的影像学检查和病人重新定位可以发现标准检查不可见的病变。该方法可提高FAP的癌前病变和恶性病变的早期发现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

VideoGIE Medicine-Gastroenterology

CiteScore

1.50

自引率

0.00%

发文量

132

审稿时长

105 days

期刊介绍： VideoGIE, an official video journal of the American Society for Gastrointestinal Endoscopy, is an Open Access, online-only journal to serve patients with digestive diseases. VideoGIE publishes original, single-blinded peer-reviewed video case reports and case series of endoscopic procedures used in the study, diagnosis, and treatment of digestive diseases. Videos demonstrate use of endoscopic systems, devices, and techniques; report outcomes of endoscopic interventions; and educate physicians and patients about gastrointestinal endoscopy. VideoGIE serves the educational needs of endoscopists in training as well as advanced endoscopists, endoscopy staff and industry, and patients. VideoGIE brings video commentaries from experts, legends, committees, and leadership of the society. Careful adherence to submission guidelines will avoid unnecessary delays, as incomplete submissions may be returned to the authors before initiation of the peer review process.