Jenna Shepherd, Lyndon Mason, Linzy Houchen-Wolloff, Karan Malhotra, Jitendra Mangwani, Irfan Ahmad, Junaid Zeb, Usman Ishaq, Jija Thomas, Kowshik Jain, Thomas Goff, Oliver Bagshaw, Henry Slade, Paul Andrzejowski, Ayoub Gomati, Chris Drake, Nimra Akram, Hamish Lowdon, AhmedKamel- Sherif, Anette Jones, Alistair Best, Mate Zabaglo, Stanley Masunda, Simon Federer, Faheem Ahmad, Ahmed Lashin, Ahmed Kaddah, Emmanuel Oladeji, Ed Dawe, Nimra Akram, Zahra Al-Hubeshy, Bhavi Patel, Mohamed Hussein, Callum Clark, Jasdeep Giddie, Raman Dega, Amirul Islam, Andy Molloy, Ben Nusir, James Chapman, David Holmes, Neville Mamoowala, Kieran Almond, Claire Wright, David Loveday, Akshdeep Bawa, Rebecca Gilmore, Kerstin Schankat, Togay Koc, Zeid Morcos, Gregory Robertson, Natal Holmes, Howard Tribe, Tim Pearkes, Ahmed Soliman, Lucia Valente, Adam Ajis, Yaser Ghani, Suresh Chandrashekhar, Ravi Kant Millan, Yahya Elhassan, Adebowale Adeniyi, Will Aspinall, Hannah Matthews, Fleur Shiers-Gelalis, Jason Ting, Stuart Place, Adam Budgen, James Stanley, Charlie Jowett, Matthew Welck, Shelain Patel, Adam Sykes, Mahesh Mamballi Thibbaiah, Hosain Hadi, Anil Haldar, Amir Gahanbani Ardakani, Priyanka Jani, Anil Prasanna, Mark Blomfield, Joanna Craven, Anubhav Malhotra, Aileen Toner, Gillian Jackson, Luke Render, Connor Ashley, Richard Limb, Brijesh Ayyaswamy, Pradeepsyam Prasad, Mr Anand, Dr Sunilraj, Suzanne Lane, Swetha Prathap, Rajiv Limaye, Sarah Johnson-Lynn, Mohit Sethi, Wajiha Zahra, Catriona Heaver, Sean Duffy, William Harries, Andrew Riddick, Amro Ghobra, Harry Kinsey, Luke Marsh, Nicole Corin, Andrew Walls, Peter Robinson, Ian Winson, Steve Lines, Felix Morriss, Zalatt Pwint, Omar Ghandour, Steve Hepple, Robert Smith, Luke Hughes, Muyed Mohamed, Debbie Fraser, Ahmed Elhalawany, James Beastall, Gerard Cousins, Perrico Nunag, Rupinderbir Deol, Rad Faroug, Karan Johal, Simon Mordecai, Miltiadis Argyropouos, Amit Chawla, Mohamed Ibrahim, Marta Pereira, Joshua McIntyre, Calum Blacklock, Scott Middleton, Robert Clayton, Aureola Tong, Claire Joyner, Mike Dean, Adrian Hughes, Kimberley Shuttlewood, Zoe Little, Jawaad Saleem, Lewis Jolly, Aman Jain, Ansar Qadri, Farhan Alvi, Jagan Jacob, Raji Reddy, Vaishnav Sateesh, Alex Hrycaiczuk, Christopher Thornhill, Gowsikan Jeyakumar, Delani Vaithilingam, Kate Potter, Bilal Jamal, Pete Chan, Tristan Barton, Derek Robinson, Selina Graham, Julian Zeolla, Smriti Kapoor, James Bailey, Ishani Mukhopadhyay, Sarina Rana, Hamza Tarig, Mahdi Qualaghassi, Sheena Seewoonarian, Barry Rose, Nilesh Makwana, Kahlan Al Kaisi, Musab Al-Musabi, Georgina Crate, Sarah Abbott, Christopher Fenner, Ryan Geleit, Sohail Yousaf, George Flanagan, Akram Uddin, Ian Reilly, Anand Pillai, Imad Madhi, Mazin Alsalihy, Khadija Elamin, Chee Rong Yip, Lucy Tew, Rohan Dahiya, Junaid Sayani, Olive Kyaw, Chan Khin, Ramla Ali, Yousufuddin Shaik, Natasha Hossain, Abhijit Guha, Melwyn Pereira, Atif Ayoub, Vlad Paraoan, Nayeem Hali, Charles Baird, Raj Kugan, Ahmad Abdallatif, Muhammad Amer Bashir, Jigyasa Saini, Henry Atkinson, Caroline Lever, Vaibhav Bansod, Kartik Iyengar, Abdul Wadood, Lara McMillan, Eugene Toh, Sophy Rymaruk, Kueni Igbagiri, Andrew Gaukroger, Matthew Solan, Christian Peacock, Ka Siu Fan, Benjamin Lau, Arjun Naik, Eleanor Tung, Siddhartha Murhekar, Mr Robbie Ray, Miss Shirley Lyle, Rabia Shaikh, Wilam Alfred, Imobhio Okhifun, Ece Cinar, Nelson Bua, Krishna Vemulapalli, Ashok Acharya, Kar Teoh, Sanil Kamat, Abhijit Bajracharya, James Reeves Mbori Ngwayi, Galal Imtiaz, Noah Blackmore, Andrew Clark, Kashed Rahman, Mark Sykes, Vinay Joseph, Miriam Day, Avadhut Kulkarni, Mohanrao Garabadi, Meraj Akhtar, Munier Hossain, Shamael Yunus, Maleeha Saleem, Joanna Fong, Michiel Simons, Paul Hodgson, Rhys Thomas, Sam Stevens, Kishore Dasari, Gurbinder Nandhara, Pritesh Kumar, Prateek Gupta, Hope Poole, Pamela Zace, Richard Gadd, John Money-Taylor, Rohit Kantharaju, Abhijit Bhosale, Suchita Bahri, Rosie Broadbent, Vladislav Kutuzov, James Gibbons, Daniel Trussler, Eve Hawley, Sabeen Akhtar, Ethan Caruana, Thomas Watson, Georgia Allison, Lynne Barr, Elda Julies, Francesca Hill, Katherine Butler, Adrian Kendal, Mark Bugeja, Justin Mooteeram, Farid Saedi, Muhammad Saad Azhar, Simon Sturdee, Halima Hussain, Sarah Sonde, Muhammad Qais Luqman, Rahy Farooq, Gareth Wells, Aneil Shenolikar, Praveen Rajan, Vijay Patil, Omer Amer, Kalim Malik, Pranavan Pavanerathan, Arijit Mallick, Ilias Seferiadis, Jamie Hind, Rebecca Morgan, Ahmed Khalaf, Adeel Ditta, Arul Ramasamy, Shahrukh Khan, Satishkumar Balasubramanian, Nicholas Fawcett, Hossam Fraig, Farouk Hamad, Daniel Marsland, Robin Elliot, Ciaran Nolan, Khalil El-Bayouk, Vivek Dhukaram, Anna Chapman, James Mckenzie, Basil Budair, Hari Prem, Mohammed Elmajee, Harshadkumar Dhirajlal Rajgor, Daniel Thurston, Erika Pond, Margaret Brooks, Samuel Everett, Mohammad Iqbal, Lysander Gourbault, Shashwat Singh, Cary Tang, Mariam Tarhini, Mr Raghubir Kankate, Mr Ioannis Aktselis, Mr Kinner Davda, Mr Arvind Vijapur, Mr Mohammed Tayyem, Ms Jackie Chau, Muhammed Alzaranky, Osman Elhassan, Kishor Chhantyal, Abhishek Arora, Zain Abiddin, Robert Kucharski, Andrea Gledhill, James Craven, Matt Cichero, Ben Yates, Ayla Newton, John Grice, Laura Beddard, Alex Thomas, Vipul Garg, Heath Taylor, Nikki Kelsall, Charline Roslee, Adelfatah Elsenosy, Miss Rebecca Martin, Miss Andrea Pujol-Nichol, Miss Natalie Carroll, Alexander Boucher, Mustafa Alward, Yuland Myint, Verity Currall, Preetha Sadasivan, Sunil Kumar, Shahrukh RezaSanjani, Maria Ciaccio, Lucky Jeyaseelan, Isabella Drummond, Neil Jones, Savan Shah, Thuwarahan Ravindrarjah, Zaid Yasen, Kunjshri Singh, Ruqaiya Al-Habsi, Lucky Jeyaseelan, Abdullah Habbiba, Thomas Walker, Maximilian Dewhurst, Nisha Glasgow, Dominic Eze, Gary Carter
{"title":"Infection following foot and ankle surgery : a subanalysis of data captured from the UK Foot and Ankle Thromboembolism (FATE) audit.","authors":"Jenna Shepherd, Lyndon Mason, Linzy Houchen-Wolloff, Karan Malhotra, Jitendra Mangwani, Irfan Ahmad, Junaid Zeb, Usman Ishaq, Jija Thomas, Kowshik Jain, Thomas Goff, Oliver Bagshaw, Henry Slade, Paul Andrzejowski, Ayoub Gomati, Chris Drake, Nimra Akram, Hamish Lowdon, AhmedKamel- Sherif, Anette Jones, Alistair Best, Mate Zabaglo, Stanley Masunda, Simon Federer, Faheem Ahmad, Ahmed Lashin, Ahmed Kaddah, Emmanuel Oladeji, Ed Dawe, Nimra Akram, Zahra Al-Hubeshy, Bhavi Patel, Mohamed Hussein, Callum Clark, Jasdeep Giddie, Raman Dega, Amirul Islam, Andy Molloy, Ben Nusir, James Chapman, David Holmes, Neville Mamoowala, Kieran Almond, Claire Wright, David Loveday, Akshdeep Bawa, Rebecca Gilmore, Kerstin Schankat, Togay Koc, Zeid Morcos, Gregory Robertson, Natal Holmes, Howard Tribe, Tim Pearkes, Ahmed Soliman, Lucia Valente, Adam Ajis, Yaser Ghani, Suresh Chandrashekhar, Ravi Kant Millan, Yahya Elhassan, Adebowale Adeniyi, Will Aspinall, Hannah Matthews, Fleur Shiers-Gelalis, Jason Ting, Stuart Place, Adam Budgen, James Stanley, Charlie Jowett, Matthew Welck, Shelain Patel, Adam Sykes, Mahesh Mamballi Thibbaiah, Hosain Hadi, Anil Haldar, Amir Gahanbani Ardakani, Priyanka Jani, Anil Prasanna, Mark Blomfield, Joanna Craven, Anubhav Malhotra, Aileen Toner, Gillian Jackson, Luke Render, Connor Ashley, Richard Limb, Brijesh Ayyaswamy, Pradeepsyam Prasad, Mr Anand, Dr Sunilraj, Suzanne Lane, Swetha Prathap, Rajiv Limaye, Sarah Johnson-Lynn, Mohit Sethi, Wajiha Zahra, Catriona Heaver, Sean Duffy, William Harries, Andrew Riddick, Amro Ghobra, Harry Kinsey, Luke Marsh, Nicole Corin, Andrew Walls, Peter Robinson, Ian Winson, Steve Lines, Felix Morriss, Zalatt Pwint, Omar Ghandour, Steve Hepple, Robert Smith, Luke Hughes, Muyed Mohamed, Debbie Fraser, Ahmed Elhalawany, James Beastall, Gerard Cousins, Perrico Nunag, Rupinderbir Deol, Rad Faroug, Karan Johal, Simon Mordecai, Miltiadis Argyropouos, Amit Chawla, Mohamed Ibrahim, Marta Pereira, Joshua McIntyre, Calum Blacklock, Scott Middleton, Robert Clayton, Aureola Tong, Claire Joyner, Mike Dean, Adrian Hughes, Kimberley Shuttlewood, Zoe Little, Jawaad Saleem, Lewis Jolly, Aman Jain, Ansar Qadri, Farhan Alvi, Jagan Jacob, Raji Reddy, Vaishnav Sateesh, Alex Hrycaiczuk, Christopher Thornhill, Gowsikan Jeyakumar, Delani Vaithilingam, Kate Potter, Bilal Jamal, Pete Chan, Tristan Barton, Derek Robinson, Selina Graham, Julian Zeolla, Smriti Kapoor, James Bailey, Ishani Mukhopadhyay, Sarina Rana, Hamza Tarig, Mahdi Qualaghassi, Sheena Seewoonarian, Barry Rose, Nilesh Makwana, Kahlan Al Kaisi, Musab Al-Musabi, Georgina Crate, Sarah Abbott, Christopher Fenner, Ryan Geleit, Sohail Yousaf, George Flanagan, Akram Uddin, Ian Reilly, Anand Pillai, Imad Madhi, Mazin Alsalihy, Khadija Elamin, Chee Rong Yip, Lucy Tew, Rohan Dahiya, Junaid Sayani, Olive Kyaw, Chan Khin, Ramla Ali, Yousufuddin Shaik, Natasha Hossain, Abhijit Guha, Melwyn Pereira, Atif Ayoub, Vlad Paraoan, Nayeem Hali, Charles Baird, Raj Kugan, Ahmad Abdallatif, Muhammad Amer Bashir, Jigyasa Saini, Henry Atkinson, Caroline Lever, Vaibhav Bansod, Kartik Iyengar, Abdul Wadood, Lara McMillan, Eugene Toh, Sophy Rymaruk, Kueni Igbagiri, Andrew Gaukroger, Matthew Solan, Christian Peacock, Ka Siu Fan, Benjamin Lau, Arjun Naik, Eleanor Tung, Siddhartha Murhekar, Mr Robbie Ray, Miss Shirley Lyle, Rabia Shaikh, Wilam Alfred, Imobhio Okhifun, Ece Cinar, Nelson Bua, Krishna Vemulapalli, Ashok Acharya, Kar Teoh, Sanil Kamat, Abhijit Bajracharya, James Reeves Mbori Ngwayi, Galal Imtiaz, Noah Blackmore, Andrew Clark, Kashed Rahman, Mark Sykes, Vinay Joseph, Miriam Day, Avadhut Kulkarni, Mohanrao Garabadi, Meraj Akhtar, Munier Hossain, Shamael Yunus, Maleeha Saleem, Joanna Fong, Michiel Simons, Paul Hodgson, Rhys Thomas, Sam Stevens, Kishore Dasari, Gurbinder Nandhara, Pritesh Kumar, Prateek Gupta, Hope Poole, Pamela Zace, Richard Gadd, John Money-Taylor, Rohit Kantharaju, Abhijit Bhosale, Suchita Bahri, Rosie Broadbent, Vladislav Kutuzov, James Gibbons, Daniel Trussler, Eve Hawley, Sabeen Akhtar, Ethan Caruana, Thomas Watson, Georgia Allison, Lynne Barr, Elda Julies, Francesca Hill, Katherine Butler, Adrian Kendal, Mark Bugeja, Justin Mooteeram, Farid Saedi, Muhammad Saad Azhar, Simon Sturdee, Halima Hussain, Sarah Sonde, Muhammad Qais Luqman, Rahy Farooq, Gareth Wells, Aneil Shenolikar, Praveen Rajan, Vijay Patil, Omer Amer, Kalim Malik, Pranavan Pavanerathan, Arijit Mallick, Ilias Seferiadis, Jamie Hind, Rebecca Morgan, Ahmed Khalaf, Adeel Ditta, Arul Ramasamy, Shahrukh Khan, Satishkumar Balasubramanian, Nicholas Fawcett, Hossam Fraig, Farouk Hamad, Daniel Marsland, Robin Elliot, Ciaran Nolan, Khalil El-Bayouk, Vivek Dhukaram, Anna Chapman, James Mckenzie, Basil Budair, Hari Prem, Mohammed Elmajee, Harshadkumar Dhirajlal Rajgor, Daniel Thurston, Erika Pond, Margaret Brooks, Samuel Everett, Mohammad Iqbal, Lysander Gourbault, Shashwat Singh, Cary Tang, Mariam Tarhini, Mr Raghubir Kankate, Mr Ioannis Aktselis, Mr Kinner Davda, Mr Arvind Vijapur, Mr Mohammed Tayyem, Ms Jackie Chau, Muhammed Alzaranky, Osman Elhassan, Kishor Chhantyal, Abhishek Arora, Zain Abiddin, Robert Kucharski, Andrea Gledhill, James Craven, Matt Cichero, Ben Yates, Ayla Newton, John Grice, Laura Beddard, Alex Thomas, Vipul Garg, Heath Taylor, Nikki Kelsall, Charline Roslee, Adelfatah Elsenosy, Miss Rebecca Martin, Miss Andrea Pujol-Nichol, Miss Natalie Carroll, Alexander Boucher, Mustafa Alward, Yuland Myint, Verity Currall, Preetha Sadasivan, Sunil Kumar, Shahrukh RezaSanjani, Maria Ciaccio, Lucky Jeyaseelan, Isabella Drummond, Neil Jones, Savan Shah, Thuwarahan Ravindrarjah, Zaid Yasen, Kunjshri Singh, Ruqaiya Al-Habsi, Lucky Jeyaseelan, Abdullah Habbiba, Thomas Walker, Maximilian Dewhurst, Nisha Glasgow, Dominic Eze, Gary Carter","doi":"10.1302/0301-620X.108B6.BJJ-2025-1345.R1","DOIUrl":null,"url":null,"abstract":"<p><strong>Aims: </strong>The UK Foot and Ankle Thromboembolism (UK-FATE) Collaborative evaluated incidence of venous thromboembolism (VTE) in foot and ankle surgery and Achilles tendon (AT) rupture. As part of the data collection, infection within 90 days was a secondary outcome. This study aimed to evaluate overall rate of superficial and deep infection following foot and ankle surgery in trauma, elective, and acute diabetic surgery.</p><p><strong>Methods: </strong>Data were collected prospectively across 68 centres in the UK for all patients who underwent foot and ankle surgery between 1 June and 30 November 2022. Over 500,000 data points were collected, including development of superficial and deep infection within 90 days of procedure and presence of comorbidities.</p><p><strong>Results: </strong>UK-FATE captured 90-day infection data for a total of 9,723 cases. When nonoperatively managed AT ruptures were excluded, infection data were available for 9,591 trauma, elective, and acute diabetic procedures. Overall superficial and deep infection rates in all procedures were 4.1% (n = 397/9,591) and 1.4% (n = 133/9,591), respectively. Both superficial (7.4% (n = 29); p < 0.001) and deep infection (8.7% (n = 34); p < 0.001) rates were highest in acute diabetic procedures. Deep infection differed between trauma (1.4% (n = 65/4,351)) and elective (0.7% (n = 34/4,785)) procedures (p < 0.001), but superficial infection rates were similar (3.9% (n = 171/4,245) and 4.1% (n = 197/4,588), respectively (p = 0.638)). On multivariate regression analysis, peripheral vascular disease (OR (odds ratio) 2.86 (95% CI 1.74 to 4.56); p < 0.001), smoking (OR 1.54 (95% CI 1.18 to 2.00); p = 0.001), diabetes (OR 1.83 (95% CI 1.35 to 2.44); p < 0.001), American Society of Anesthesiologists grade III to IV (OR 1.94 (95% CI 1.37 to 2.73); p < 0.001), and chemical VTE prophylaxis (OR 1.38 (95% CI 1.03 to 1.85); p = 0.031) were independent predictors for developing infection.</p><p><strong>Conclusion: </strong>Rates of superficial and deep infection were significantly higher in patients with acute diabetic surgery. Deep infection rates were higher in trauma than in elective surgery, but superficial infection rates were similar. Comorbidities and smoking affected infection rate in foot and ankle surgery, and should be optimized preoperatively and considered in postoperative monitoring.</p>","PeriodicalId":48944,"journal":{"name":"Bone & Joint Journal","volume":"108-B 6","pages":"781-786"},"PeriodicalIF":4.8000,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bone & Joint Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1302/0301-620X.108B6.BJJ-2025-1345.R1","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
引用次数: 0
Abstract
Aims: The UK Foot and Ankle Thromboembolism (UK-FATE) Collaborative evaluated incidence of venous thromboembolism (VTE) in foot and ankle surgery and Achilles tendon (AT) rupture. As part of the data collection, infection within 90 days was a secondary outcome. This study aimed to evaluate overall rate of superficial and deep infection following foot and ankle surgery in trauma, elective, and acute diabetic surgery.
Methods: Data were collected prospectively across 68 centres in the UK for all patients who underwent foot and ankle surgery between 1 June and 30 November 2022. Over 500,000 data points were collected, including development of superficial and deep infection within 90 days of procedure and presence of comorbidities.
Results: UK-FATE captured 90-day infection data for a total of 9,723 cases. When nonoperatively managed AT ruptures were excluded, infection data were available for 9,591 trauma, elective, and acute diabetic procedures. Overall superficial and deep infection rates in all procedures were 4.1% (n = 397/9,591) and 1.4% (n = 133/9,591), respectively. Both superficial (7.4% (n = 29); p < 0.001) and deep infection (8.7% (n = 34); p < 0.001) rates were highest in acute diabetic procedures. Deep infection differed between trauma (1.4% (n = 65/4,351)) and elective (0.7% (n = 34/4,785)) procedures (p < 0.001), but superficial infection rates were similar (3.9% (n = 171/4,245) and 4.1% (n = 197/4,588), respectively (p = 0.638)). On multivariate regression analysis, peripheral vascular disease (OR (odds ratio) 2.86 (95% CI 1.74 to 4.56); p < 0.001), smoking (OR 1.54 (95% CI 1.18 to 2.00); p = 0.001), diabetes (OR 1.83 (95% CI 1.35 to 2.44); p < 0.001), American Society of Anesthesiologists grade III to IV (OR 1.94 (95% CI 1.37 to 2.73); p < 0.001), and chemical VTE prophylaxis (OR 1.38 (95% CI 1.03 to 1.85); p = 0.031) were independent predictors for developing infection.
Conclusion: Rates of superficial and deep infection were significantly higher in patients with acute diabetic surgery. Deep infection rates were higher in trauma than in elective surgery, but superficial infection rates were similar. Comorbidities and smoking affected infection rate in foot and ankle surgery, and should be optimized preoperatively and considered in postoperative monitoring.
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