{"title":"Repair strategy for acute type A aortic dissection in a regional center.","authors":"Kotaro Mukasa, Shinichiro Abe, Soichi Asano","doi":"10.1177/02184923261455651","DOIUrl":null,"url":null,"abstract":"<p><p>BackgroundThe optimal extent of repair for DeBakey type I acute aortic dissection remains controversial, particularly in low- to medium-volume centers. We compared outcomes of ascending and arch replacement under a tear-oriented strategy in DeBakey type I dissection.MethodsWe retrospectively analyzed 114 consecutive patients with acute DeBakey type I dissection between April 2008 and July 2025 at a regional cardiovascular center. Ascending aortic replacement was performed in 55 patients, and arch replacement, including both partial and total arch replacement, in 59 patients. The primary endpoint was overall survival. Secondary endpoints included in-hospital mortality, major complications, and open aortic reoperation.ResultsArch replacement required longer operative, cardiopulmonary bypass, aortic cross-clamp, and circulatory arrest times. In-hospital mortality was 5.5% after ascending aortic replacement and 13.6% after arch replacement (<i>P</i> = 0.143). Rates of major complications were comparable between groups. Long-term survival was better after ascending aortic replacement than after arch replacement (5-year, 87.1% vs 69.4%; 10-year, 83.5% vs 59.8%; <i>P</i> = 0.015). Freedom from open aortic reoperation was similar between groups (5-year, 90.4% vs 88.3%; 10-year, 70.2% vs 88.3%; <i>P </i>= 0.201). In the subgroup analysis restricted to patients with an intimal tear in the aortic root or ascending aorta, there were no differences in the primary or secondary endpoints.ConclusionsA tear-oriented limited replacement strategy appears reasonable in centers with limited volume of acute type A dissection repair.</p>","PeriodicalId":35950,"journal":{"name":"ASIAN CARDIOVASCULAR & THORACIC ANNALS","volume":" ","pages":"525-534"},"PeriodicalIF":0.7000,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ASIAN CARDIOVASCULAR & THORACIC ANNALS","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/02184923261455651","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/5/29 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
BackgroundThe optimal extent of repair for DeBakey type I acute aortic dissection remains controversial, particularly in low- to medium-volume centers. We compared outcomes of ascending and arch replacement under a tear-oriented strategy in DeBakey type I dissection.MethodsWe retrospectively analyzed 114 consecutive patients with acute DeBakey type I dissection between April 2008 and July 2025 at a regional cardiovascular center. Ascending aortic replacement was performed in 55 patients, and arch replacement, including both partial and total arch replacement, in 59 patients. The primary endpoint was overall survival. Secondary endpoints included in-hospital mortality, major complications, and open aortic reoperation.ResultsArch replacement required longer operative, cardiopulmonary bypass, aortic cross-clamp, and circulatory arrest times. In-hospital mortality was 5.5% after ascending aortic replacement and 13.6% after arch replacement (P = 0.143). Rates of major complications were comparable between groups. Long-term survival was better after ascending aortic replacement than after arch replacement (5-year, 87.1% vs 69.4%; 10-year, 83.5% vs 59.8%; P = 0.015). Freedom from open aortic reoperation was similar between groups (5-year, 90.4% vs 88.3%; 10-year, 70.2% vs 88.3%; P = 0.201). In the subgroup analysis restricted to patients with an intimal tear in the aortic root or ascending aorta, there were no differences in the primary or secondary endpoints.ConclusionsA tear-oriented limited replacement strategy appears reasonable in centers with limited volume of acute type A dissection repair.
背景DeBakey I型急性主动脉夹层的最佳修复范围仍然存在争议,特别是在中、小容积中心。我们比较了DeBakey I型夹层在撕裂导向策略下的上升和弓置换术的结果。方法回顾性分析2008年4月至2025年7月在某地区心血管中心连续收治的114例急性DeBakey I型夹层患者。55例患者行升主动脉置换术,59例患者行足弓置换术,包括部分和全部足弓置换术。主要终点是总生存期。次要终点包括住院死亡率、主要并发症和主动脉切开再手术。结果人工血管置换术需要更长的手术时间、体外循环、主动脉交叉夹夹和循环停搏时间。升主动脉置换术的住院死亡率为5.5%,弓置换术的住院死亡率为13.6% (P = 0.143)。两组间主要并发症发生率具有可比性。升主动脉置换术的长期生存率优于弓置换术(5年,87.1% vs 69.4%; 10年,83.5% vs 59.8%; P = 0.015)。两组再开腹主动脉手术的自由度相似(5年,90.4% vs 88.3%; 10年,70.2% vs 88.3%; P = 0.201)。在仅限于主动脉根部或升主动脉内膜撕裂患者的亚组分析中,主要终点和次要终点没有差异。结论在容量有限的中心急性A型夹层修复中,以泪为导向的有限置换策略是合理的。
期刊介绍:
The Asian Cardiovascular and Thoracic Annals is an international peer-reviewed journal pertaining to cardiovascular and thoracic medicine. Besides original clinical manuscripts, we welcome research reports, product reviews, reports of new techniques, and findings of special significance to Asia and the Pacific Rim. Case studies that have significant novel original observations, are instructive, include adequate methodological details and provide conclusions. Workshop proceedings, meetings and book reviews, letters to the editor, and meeting announcements are encouraged along with relevant articles from authors.