Anne J H Vochteloo, Camiel J Smees, Quinty Teggeler, Judith Olde Heuvel, Michelle M A Kip, Xavier G L V Pouwels
{"title":"Exploring the cost-effectiveness of 3-D-guided versus traditional 2-D corrective osteotomy in patients with a distal radius malunion.","authors":"Anne J H Vochteloo, Camiel J Smees, Quinty Teggeler, Judith Olde Heuvel, Michelle M A Kip, Xavier G L V Pouwels","doi":"10.1186/s12962-026-00756-7","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Distal radius malunion is a frequent complication after a distal radius fracture, impairing function and quality of life. Corrective osteotomy using conventional two-dimensional (2-D) planning often fails to achieve optimal alignment, leading to residual symptoms and revision surgery. Growing evidence shows that three-dimensional (3-D) planning with patient-specific surgical guides has better radiographic and clinical outcomes and fewer complications, but at increased upfront costs.</p><p><strong>Methods: </strong>We developed a health state transition model to assess the cost-effectiveness of 3-D versus 2-D based surgery in the Netherlands over a five-year time horizon from a societal perspective. Clinical outcomes of 3-D, including transition probabilities, were obtained from a clinical cohort, whereas literature informed 2-D transition probabilities. Literature was used to obtain costs, and utility values. Outcomes of interests were the number of revisions, quality-adjusted life years (QALYs) and societal costs in each strategy. All 3-D analyses and guide development were performed in our in-house 3-D lab.</p><p><strong>Results: </strong>Notably, revisions performed for nonunion or implant failure were reduced by 179 per 1,000 patients in the 3-D strategy. Overall, 3-D yielded slightly higher QALYs (+ 0.007) and lower costs (-€219), primarily due to fewer revisions performed for nonunion or implant failure and reduced productivity losses.</p><p><strong>Conclusion: </strong>Using this model, 3-D-guided corrective osteotomy (supported by an in-house 3-D lab) is anticipated to be cost-effective versus 2-D-planned corrective osteotomy from a Dutch societal perspective; it potentially yields a modest improvement in health outcomes alongside a slight reduction in costs. However further clinical validation, including prospective collection of clinical outcome data, is needed to confirm these findings in real-world practice.</p>","PeriodicalId":47054,"journal":{"name":"Cost Effectiveness and Resource Allocation","volume":" ","pages":""},"PeriodicalIF":3.1000,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13377804/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cost Effectiveness and Resource Allocation","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12962-026-00756-7","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"HEALTH POLICY & SERVICES","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: Distal radius malunion is a frequent complication after a distal radius fracture, impairing function and quality of life. Corrective osteotomy using conventional two-dimensional (2-D) planning often fails to achieve optimal alignment, leading to residual symptoms and revision surgery. Growing evidence shows that three-dimensional (3-D) planning with patient-specific surgical guides has better radiographic and clinical outcomes and fewer complications, but at increased upfront costs.
Methods: We developed a health state transition model to assess the cost-effectiveness of 3-D versus 2-D based surgery in the Netherlands over a five-year time horizon from a societal perspective. Clinical outcomes of 3-D, including transition probabilities, were obtained from a clinical cohort, whereas literature informed 2-D transition probabilities. Literature was used to obtain costs, and utility values. Outcomes of interests were the number of revisions, quality-adjusted life years (QALYs) and societal costs in each strategy. All 3-D analyses and guide development were performed in our in-house 3-D lab.
Results: Notably, revisions performed for nonunion or implant failure were reduced by 179 per 1,000 patients in the 3-D strategy. Overall, 3-D yielded slightly higher QALYs (+ 0.007) and lower costs (-€219), primarily due to fewer revisions performed for nonunion or implant failure and reduced productivity losses.
Conclusion: Using this model, 3-D-guided corrective osteotomy (supported by an in-house 3-D lab) is anticipated to be cost-effective versus 2-D-planned corrective osteotomy from a Dutch societal perspective; it potentially yields a modest improvement in health outcomes alongside a slight reduction in costs. However further clinical validation, including prospective collection of clinical outcome data, is needed to confirm these findings in real-world practice.
期刊介绍:
Cost Effectiveness and Resource Allocation is an Open Access, peer-reviewed, online journal that considers manuscripts on all aspects of cost-effectiveness analysis, including conceptual or methodological work, economic evaluations, and policy analysis related to resource allocation at a national or international level. Cost Effectiveness and Resource Allocation is aimed at health economists, health services researchers, and policy-makers with an interest in enhancing the flow and transfer of knowledge relating to efficiency in the health sector. Manuscripts are encouraged from researchers based in low- and middle-income countries, with a view to increasing the international economic evidence base for health.