Exploring the cost-effectiveness of 3-D-guided versus traditional 2-D corrective osteotomy in patients with a distal radius malunion.

IF 3.1 4区 医学 Q3 HEALTH POLICY & SERVICES
Anne J H Vochteloo, Camiel J Smees, Quinty Teggeler, Judith Olde Heuvel, Michelle M A Kip, Xavier G L V Pouwels
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Abstract

Introduction: Distal radius malunion is a frequent complication after a distal radius fracture, impairing function and quality of life. Corrective osteotomy using conventional two-dimensional (2-D) planning often fails to achieve optimal alignment, leading to residual symptoms and revision surgery. Growing evidence shows that three-dimensional (3-D) planning with patient-specific surgical guides has better radiographic and clinical outcomes and fewer complications, but at increased upfront costs.

Methods: We developed a health state transition model to assess the cost-effectiveness of 3-D versus 2-D based surgery in the Netherlands over a five-year time horizon from a societal perspective. Clinical outcomes of 3-D, including transition probabilities, were obtained from a clinical cohort, whereas literature informed 2-D transition probabilities. Literature was used to obtain costs, and utility values. Outcomes of interests were the number of revisions, quality-adjusted life years (QALYs) and societal costs in each strategy. All 3-D analyses and guide development were performed in our in-house 3-D lab.

Results: Notably, revisions performed for nonunion or implant failure were reduced by 179 per 1,000 patients in the 3-D strategy. Overall, 3-D yielded slightly higher QALYs (+ 0.007) and lower costs (-€219), primarily due to fewer revisions performed for nonunion or implant failure and reduced productivity losses.

Conclusion: Using this model, 3-D-guided corrective osteotomy (supported by an in-house 3-D lab) is anticipated to be cost-effective versus 2-D-planned corrective osteotomy from a Dutch societal perspective; it potentially yields a modest improvement in health outcomes alongside a slight reduction in costs. However further clinical validation, including prospective collection of clinical outcome data, is needed to confirm these findings in real-world practice.

探讨在桡骨远端畸形愈合患者中三维引导与传统二维矫正截骨术的成本效益。
简介:桡骨远端不愈合是桡骨远端骨折后常见的并发症,影响功能和生活质量。使用传统的二维(2-D)计划矫正截骨术常常不能达到最佳对齐,导致残留症状和翻修手术。越来越多的证据表明,三维(3-D)计划与患者特定的手术指南有更好的放射学和临床效果,并发症更少,但前期成本增加。方法:我们开发了一个健康状态转换模型,从社会角度评估荷兰5年时间内3d与2d手术的成本效益。3-D的临床结果,包括转换概率,是从临床队列中获得的,而文献报告了2-D的转换概率。文献被用来获取成本和效用价值。关注的结果是每种策略的修订次数、质量调整生命年(QALYs)和社会成本。所有的三维分析和导联开发都在我们内部的三维实验室进行。结果:值得注意的是,在3d策略中,治疗骨不连或种植体失败的患者的翻修率降低了179 / 1000。总体而言,3-D的QALYs略高(+ 0.007),成本较低(- 219欧元),主要是由于不愈合或植入物失败的修复手术较少,降低了生产率损失。结论:从荷兰社会的角度来看,使用该模型,3d引导的矫正截骨术(由内部3d实验室支持)预计比2d计划的矫正截骨术更具成本效益;它可能带来健康结果的适度改善,同时略微降低成本。然而,需要进一步的临床验证,包括前瞻性的临床结果数据收集,以在现实世界的实践中证实这些发现。
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来源期刊
Cost Effectiveness and Resource Allocation
Cost Effectiveness and Resource Allocation HEALTH POLICY & SERVICES-
CiteScore
3.40
自引率
4.30%
发文量
59
审稿时长
34 weeks
期刊介绍: Cost Effectiveness and Resource Allocation is an Open Access, peer-reviewed, online journal that considers manuscripts on all aspects of cost-effectiveness analysis, including conceptual or methodological work, economic evaluations, and policy analysis related to resource allocation at a national or international level. Cost Effectiveness and Resource Allocation is aimed at health economists, health services researchers, and policy-makers with an interest in enhancing the flow and transfer of knowledge relating to efficiency in the health sector. Manuscripts are encouraged from researchers based in low- and middle-income countries, with a view to increasing the international economic evidence base for health.
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