S Varghese, K Cinnamond, B Malek, E McMonagle, L Casserly
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引用次数: 0
Abstract
Presentation: A 42-year-old man presented with a four-week history of nausea, vomiting, and abdominal pain, ultimately attributed to chronic overuse of calcium carbonate tablets for gastroesophageal reflux disease (GORD).
Diagnosis: Diagnostic evaluation revealed hypercalcaemia, metabolic alkalosis, and acute kidney injury, necessitating intravenous fluid administration and cessation of calcium carbonate tablet consumption. Comprehensive investigations excluded alternative aetiologies, confirming Milk-Alkali Syndrome (MAS).
Treatment: Management involved cessation of calcium carbonate intake, aggressive intravenous fluid administration, and a single 4 mg dose of zoledronic acid. The patient was discharged with esomeprazole. His serum calcium normalised within six days, and creatinine showed further improvement at the 18-month follow-up, underscoring the importance of prompt recognition and intervention.
Discussion: This case emphasizes the need for awareness among healthcare providers regarding MAS as a potential consequence of over-the-counter antacid use and underscores the importance of vigilant medication history review and patient education to prevent MAS-related complications.
期刊介绍：
Since its inception in 1867, the Journal of the Medical Association of Ireland and now in its present format, the Irish Medical Journal, has provided the medical community in Ireland with an invaluable service. As one of the leading biomedical publications in Ireland, it has sought to continue the education of medical students and postgraduates through scientific research, review articles and updates on contemporary clinical practices while providing an ongoing forum for medical debate. A measure of our stature is that we are listed in the Index Medicus and issued annually with a citation factor from the Institute for Scientific Information.
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