Effect of Subcutaneous Negative Suction Drain on Surgical Site Infection Following Colorectal Surgery: A Systematic Review and Meta-Analysis

IF 1.5 4区医学 Q3 SURGERY

ANZ Journal of Surgery Pub Date : 2026-09-02 Epub Date: 2026-05-20 DOI:10.1111/ans.70659

Bishnu Prasad Kandel, Prajjwol Luitel, Amit Yadav, Rukesh Yadav, Sujan Shrestha, Anup Chalise

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引用次数: 0

Abstract

Background

Surgical site infections (SSIs) are among the most common complications following colorectal surgery. This study aimed to systematically review existing evidence on the outcomes of subcutaneous negative suction drain versus no drain in adults undergoing colorectal surgeries.

Methods

A systematic review and meta-analysis was conducted to compare the SSI rates between subcutaneous negative suction drain and the no-drain in adults (18 years or older) undergoing colorectal surgery. Randomized controlled trials (RCTs), prospective, or retrospective studies till 2025 reporting use of subcutaneous negative suction drain in elective and emergency colorectal surgeries were included. SSI was defined based on Center for Disease Control and Prevention (CDC) criteria. Results were expressed as Relative Risk (RR) and Confidence interval (CI) of 95%. A p value < 0.05 was considered statistically significant.

Results

Combined data from 2177 patients across 10 studies (four: RCTs, five: retrospective cohort, and one: prospective cohort) showed a significant reduction in overall SSIs by 60% (RR = 0.40; 95% CI, 0.30–0.53; p < 0.0001) in groups with a subcutaneous negative suction drain compared to those without. There was a significant reduction in superficial SSIs by 58% (RR = 0.42; 95% CI, 0.26–0.66; p = 0.0002). There was no significant reduction in deep SSIs and organ-space SSIs. The included studies were of medium to high quality.

Conclusions

Subcutaneous negative suction drains reduce overall and superficial SSI after colorectal surgery, but do not affect deep or organ-space infection.

Originality Statement

This paper provides updated evidence demonstrating that subcutaneous negative suction drains significantly reduce overall and superficial surgical site infections after colorectal surgery, and acknowledges their limited effect on deep and organ-space infections, supporting selective use.

Trial Registration: The study protocol was registered with PROSPERO international prospective register of systematic Reviews (Registration ID: CRD420251012636)

查看原文本刊更多论文

结直肠手术后皮下负吸引引流对手术部位感染的影响：系统回顾和荟萃分析。

背景：手术部位感染是结直肠手术后最常见的并发症之一。本研究旨在系统地回顾成人结肠直肠手术中皮下负吸引引流与无引流的现有证据。方法：通过系统回顾和荟萃分析，比较18岁及以上成人结直肠手术患者皮下负吸引流和无引流的SSI发生率。随机对照试验（RCTs），前瞻性或回顾性研究，直到2025年报告在择期和紧急结肠直肠手术中使用皮下负吸引引流。SSI是根据疾病控制和预防中心（CDC）的标准定义的。结果以相对危险度（RR）和置信区间（CI）为95%表示。结果：来自10项研究（4项：随机对照试验，5项：回顾性队列，1项：前瞻性队列）的2177例患者的综合数据显示，总体SSI显著降低60% (RR = 0.40; 95% CI, 0.30-0.53； p结论：皮下负吸引引流可减少结直肠手术后总体和浅表SSI，但不影响深部或器官间隙感染。原创性声明：本文提供了最新的证据，证明皮下负吸引引流可显著减少结直肠手术后手术部位的整体和浅表感染，并承认其对深部和器官空间感染的影响有限，支持选择性使用。试验注册：研究方案已在普洛斯彼罗国际前瞻性系统评价注册（注册ID: CRD420251012636）注册。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ANZ Journal of Surgery 医学-外科

CiteScore

2.50

自引率

11.80%

发文量

720

审稿时长

2 months

期刊介绍： ANZ Journal of Surgery is published by Wiley on behalf of the Royal Australasian College of Surgeons to provide a medium for the publication of peer-reviewed original contributions related to clinical practice and/or research in all fields of surgery and related disciplines. It also provides a programme of continuing education for surgeons. All articles are peer-reviewed by at least two researchers expert in the field of the submitted paper.