Solid Boron Targets Fabricated by Free Sintering for Nanoparticle Synthesis in Boron Neutron Capture Therapy Applications

IF 0.5 4区材料科学 Q4 MATERIALS SCIENCE, MULTIDISCIPLINARY

Inorganic Materials Pub Date : 2026-05-19 DOI:10.1134/S0020168526700408

N. V. Karpov, A. A. Fronya, E. I. Mavreshko, S. M. Klimentov, D. I. Tselikov, D. S. Petrunya, V. V. Dubov, P. V. Karpuk, P. S. Sokolov, I. Yu. Komendo, I. N. Zavestovskaya

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引用次数: 0

Abstract

This work presents the results of a study on methods for obtaining elemental boron-10 nanoparticles for use in boron neutron capture therapy. A technology for fabricating solid-state targets from ¹⁰B-enriched powder by free sintering under reduced pressure has been developed. Nanoparticles were synthesized via femtosecond laser ablation in liquid. The influence of the sintering conditions of the targets on the productivity of the process and the characteristics of the resulting nanoparticles was investigated. Colloidal solutions of nanoparticles with average sizes of 50–60 nm and a narrow size distribution were obtained. It was found that optimizing the sintering parameters allows for a twofold increase in the productivity of the laser ablation synthesis. The results demonstrate the potential of the developed approach for producing elemental boron-10 nanoparticles required for effective boron neutron capture therapy.

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自由烧结制备纳米固体硼靶在硼中子俘获治疗中的应用

这项工作提出了一项研究的结果，获得元素硼-10纳米粒子用于硼中子捕获治疗。研究了以富10b粉体为原料，采用减压自由烧结法制备固体靶材的工艺。采用飞秒激光烧蚀法在液体中合成纳米颗粒。研究了烧结条件对烧结效率的影响以及所制得的纳米颗粒的特性。得到的胶体溶液平均粒径为50 ~ 60 nm，粒径分布较窄。结果表明，优化烧结参数可使激光烧蚀合成的生产率提高两倍。结果表明，开发的方法具有生产有效硼中子捕获治疗所需的元素硼-10纳米颗粒的潜力。

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来源期刊

Inorganic Materials 工程技术-材料科学：综合

CiteScore

1.40

自引率

25.00%

发文量

审稿时长

3-6 weeks

期刊介绍： Inorganic Materials is a journal that publishes reviews and original articles devoted to chemistry, physics, and applications of various inorganic materials including high-purity substances and materials. The journal discusses phase equilibria, including P–T–X diagrams, and the fundamentals of inorganic materials science, which determines preparatory conditions for compounds of various compositions with specified deviations from stoichiometry. Inorganic Materials is a multidisciplinary journal covering all classes of inorganic materials. The journal welcomes manuscripts from all countries in the English or Russian language.