A Novel Reduced Graphene Oxide-Based Biosensor for Fast Detection of Thrombin

IF 0.5 4区材料科学 Q4 MATERIALS SCIENCE, MULTIDISCIPLINARY

Inorganic Materials Pub Date : 2026-05-19 DOI:10.1134/S002016852670024X

M. I. Trukhanova, D. D. Levin, K. A. Rayanova, S. I. Babenko, A. S. Bryleva, K. V. Kanaev, R. R. Nigamatullina, A. D. Sudakova, A. V. Shchegolkov, N. V. Myasishcheva, I. A. Komarov

引用次数: 0

Abstract

In this article, we described a successful approach to deposition and further local reduction of graphene oxide film for formation of biosensor. We used improved graphene oxide suspension with additional organic solvent by which we obtained better wettability of PET substrate. By local laser reduction of graphene oxide film we made sensor topology with different reduction level. We used thrombin aptamer to form sensitive layer of a biosensor and showed high sensitivity and selectivity of sensor that can be used for new point-of-care devices and personalized medicine in the future.

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一种用于凝血酶快速检测的新型还原氧化石墨烯生物传感器

在本文中，我们描述了一种成功的沉积和进一步局部还原氧化石墨烯膜的方法，以形成生物传感器。我们使用添加有机溶剂的改进氧化石墨烯悬浮液，获得了更好的PET基板润湿性。通过激光局部还原氧化石墨烯薄膜，制作出不同还原程度的传感器拓扑结构。我们利用凝血酶适体形成生物传感器的敏感层，显示出传感器的高灵敏度和选择性，可用于未来的新型点护理设备和个性化医疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Inorganic Materials 工程技术-材料科学：综合

CiteScore

1.40

自引率

25.00%

发文量

审稿时长

3-6 weeks

期刊介绍： Inorganic Materials is a journal that publishes reviews and original articles devoted to chemistry, physics, and applications of various inorganic materials including high-purity substances and materials. The journal discusses phase equilibria, including P–T–X diagrams, and the fundamentals of inorganic materials science, which determines preparatory conditions for compounds of various compositions with specified deviations from stoichiometry. Inorganic Materials is a multidisciplinary journal covering all classes of inorganic materials. The journal welcomes manuscripts from all countries in the English or Russian language.