Recovery Effects of Alginate Film and Thermal Nursing in Thoracoscopic Surgery Patients

IF 1.3 4区 材料科学 Q4 MATERIALS SCIENCE, MULTIDISCIPLINARY
Sen Lu, Jie Liu, Juan Li, Shasha Li, Yuxia Wang, Xiaolong SONG, Xingyu Chen
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Abstract

The healing process of postoperative wounds is a dynamic and complex. Thoracoscopic surgery, as a new minimally invasive technique in thoracic surgery, is of great significance in exploring the postoperative recovery quality of patients undergoing this surgery. Therefore, this study uses micro controlled flow spinning technology to prepare a calcium alginate fiber coating (CaAFC) film using materials such as sodium alginate (SA). Combined with thermal insulation nursing during the recovery period, the effect of this film was explored in patients undergoing thoracoscopic general anesthesia surgery (TGAS), and it was applied in animal experiments simulating TGAS. The results showed that the permeability of the CaAFC was 93 g/m2·24 h, the porosity was 73 %, and the water absorption rate was 21.5 g/g, demonstrating good breathability and water absorption. The relative growth rate (RGR) of HaCaT cells under CaAFC was 1.52, and the stress fiber staining intensity (SFSI) was 1.31, both of which were higher than the other two dressings. These findings indicated that the material was non-toxic to cells and could significantly improve cell activity. The wound healing rate of mice treated with CaAFC on the 15th day after surgery was 96.3 %, which was significantly higher than that of mice treated with traditional alginate medical dressings (TAMD) and medical gauze (MG). These results indicated that CaAFC could promote wound healing. The above results indicate that the CaAFC has good breathability, water absorption, and antibacterial properties. Moreover, it can significantly promote wound healing, increase cell activity, reduce postoperative infection risk, and provide support for improving postoperative care for patients undergoing thoracoscopy surgery in clinical practice.
海藻酸盐膜及热护理在胸腔镜手术患者中的恢复效果
术后伤口的愈合过程是一个动态的、复杂的过程。胸腔镜手术作为一种新型的胸外科微创技术,对探讨胸腔镜手术患者的术后恢复质量具有重要意义。因此,本研究采用微控流动纺丝技术,以海藻酸钠(SA)等材料制备海藻酸钙纤维涂层(CaAFC)膜。结合恢复期的保温护理,探讨该膜在胸腔镜全麻手术(TGAS)患者中的应用效果,并将其应用于模拟TGAS的动物实验。结果表明,CaAFC的透气性为93 g/m2·24 h,孔隙率为73%,吸水率为21.5 g/g,具有良好的透气性和吸水性。CaAFC处理下HaCaT细胞的相对生长率(RGR)为1.52,应力纤维染色强度(SFSI)为1.31,均高于其他两种敷料。这些结果表明,该物质对细胞无毒,并能显著提高细胞活性。术后第15天CaAFC治疗小鼠创面愈合率为96.3%,明显高于传统海藻酸盐医用敷料(TAMD)和医用纱布(MG)治疗小鼠。提示CaAFC具有促进创面愈合的作用。上述结果表明,CaAFC具有良好的透气性、吸水性和抗菌性能。并能显著促进创面愈合,增加细胞活性,降低术后感染风险,为临床改进胸腔镜手术患者的术后护理提供支持。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Materials Science
Materials Science 工程技术-材料科学:综合
CiteScore
1.60
自引率
44.40%
发文量
63
审稿时长
4-8 weeks
期刊介绍: Materials Science reports on current research into such problems as cracking, fatigue and fracture, especially in active environments as well as corrosion and anticorrosion protection of structural metallic and polymer materials, and the development of new materials.
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