Mitchell Harrah, Abdul Mohaimen Safi, Sadhu Moka, Ramesh Ayyala, Ashwin B Parthasarathy
{"title":"Low-cost optical system for laser phacoemulsification of cataracts.","authors":"Mitchell Harrah, Abdul Mohaimen Safi, Sadhu Moka, Ramesh Ayyala, Ashwin B Parthasarathy","doi":"10.1117/1.BIOS.2.2.022304","DOIUrl":null,"url":null,"abstract":"<p><strong>Significance: </strong>Laser-based phacoemulsification is the preferred treatment for surgical removal of cataracts in the eye. Conventional methods of laser phacoemulsification use expensive, high-powered lasers that use femtosecond pulses to soften and emulsify cataracts, resulting in low- to middle-income countries relying on methods that lead to longer recovery times and higher rates of infection and astigmatism.</p><p><strong>Aim: </strong>We introduce and demonstrate the potential of laser phacoemulsification using a millisecond pulsed laser that can be realized using a low-cost diode laser.</p><p><strong>Approach: </strong>We show proof of concept for this device using computer simulations in COMSOL and with a prototype instrument tested on different tissue-simulating phantoms.</p><p><strong>Results: </strong>Our experiments show that the millisecond pulsed laser liquifies cataract-like tissues only at the point of illumination.</p><p><strong>Conclusions: </strong>A low-cost device for phacoemulsification can potentially reduce the burden of cataract surgeries in low-resource settings.</p>","PeriodicalId":519981,"journal":{"name":"Biophotonics discovery","volume":"2 2","pages":"022304"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13098750/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biophotonics discovery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1117/1.BIOS.2.2.022304","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Significance: Laser-based phacoemulsification is the preferred treatment for surgical removal of cataracts in the eye. Conventional methods of laser phacoemulsification use expensive, high-powered lasers that use femtosecond pulses to soften and emulsify cataracts, resulting in low- to middle-income countries relying on methods that lead to longer recovery times and higher rates of infection and astigmatism.
Aim: We introduce and demonstrate the potential of laser phacoemulsification using a millisecond pulsed laser that can be realized using a low-cost diode laser.
Approach: We show proof of concept for this device using computer simulations in COMSOL and with a prototype instrument tested on different tissue-simulating phantoms.
Results: Our experiments show that the millisecond pulsed laser liquifies cataract-like tissues only at the point of illumination.
Conclusions: A low-cost device for phacoemulsification can potentially reduce the burden of cataract surgeries in low-resource settings.