Low-cost optical system for laser phacoemulsification of cataracts.

Biophotonics discovery Pub Date : 2025-04-29 eCollection Date: 2025-04-01 DOI:10.1117/1.BIOS.2.2.022304
Mitchell Harrah, Abdul Mohaimen Safi, Sadhu Moka, Ramesh Ayyala, Ashwin B Parthasarathy
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Abstract

Significance: Laser-based phacoemulsification is the preferred treatment for surgical removal of cataracts in the eye. Conventional methods of laser phacoemulsification use expensive, high-powered lasers that use femtosecond pulses to soften and emulsify cataracts, resulting in low- to middle-income countries relying on methods that lead to longer recovery times and higher rates of infection and astigmatism.

Aim: We introduce and demonstrate the potential of laser phacoemulsification using a millisecond pulsed laser that can be realized using a low-cost diode laser.

Approach: We show proof of concept for this device using computer simulations in COMSOL and with a prototype instrument tested on different tissue-simulating phantoms.

Results: Our experiments show that the millisecond pulsed laser liquifies cataract-like tissues only at the point of illumination.

Conclusions: A low-cost device for phacoemulsification can potentially reduce the burden of cataract surgeries in low-resource settings.

激光白内障超声乳化手术的低成本光学系统。
意义:激光超声乳化术是眼内白内障手术摘除的首选治疗方法。传统的激光超声乳化方法使用昂贵的高功率激光器,使用飞秒脉冲来软化和乳化白内障,导致中低收入国家依赖于导致较长恢复时间和较高感染率和散光率的方法。目的:介绍并论证利用低成本二极管激光器实现的毫秒脉冲激光超声乳化的潜力。方法:我们使用COMSOL中的计算机模拟和在不同组织模拟模型上测试的原型仪器展示了该设备的概念证明。结果:我们的实验表明,毫秒脉冲激光只在照射点液化白内障样组织。结论:一种低成本的超声乳化设备可以潜在地减轻资源匮乏地区白内障手术的负担。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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