Robert Fleck, Melissa G Medina, Christopher K Mehta, Beth Whippo, Yunda Wang, Anirudha S Chandrabhatla, Kira Gerweck, Meilynn Shi, S Chris Malaisrie
{"title":"A modified David V: Technique and outcomes from a large single centre experience.","authors":"Robert Fleck, Melissa G Medina, Christopher K Mehta, Beth Whippo, Yunda Wang, Anirudha S Chandrabhatla, Kira Gerweck, Meilynn Shi, S Chris Malaisrie","doi":"10.1177/02184923261433401","DOIUrl":null,"url":null,"abstract":"<p><p>IntroductionReplacement of the aortic root with a composite valve-graft and coronary reimplantation is the most widely performed operation for patients requiring aortic root replacement; however valve sparing operations have been developed to preserve the aortic valve in certain populations. Since they were first introduced, the remodeling and reimplantation techniques have undergone many refinements and modifications. We describe the technical steps and outcomes of a modified David V procedure, adapted from the Stanford modification, performed at our institution.MethodsBetween November 2007 and March 2025, 417 patients underwent valve-sparing aortic root replacement at our institution. Of those, 185 patients underwent an adapted Stanford modification of valve-sparing aortic root replacement. A retrospective review of these patients was performed from a prospectively maintained institutional database.ResultsMean age was 47.6 ± 15.7 years and 81% were male. About 20.5% of patients had a heritable thoracic aortic disorder and 22.1% had a bicuspid aortic valve. The technique of our modified David V procedure is described. There was one post-operative mortality (0.5%) and no 30-day reinterventions. Early postoperative echocardiographic follow-up within 90 days was available in 91% of patients (<i>n</i> = 168), with no cases of greater than moderate aortic insufficiency. Survival at 1, 5, and 10 years was 99%, 98%, and 92%, respectively. Freedom from aortic valve or aortic re-operation at 1, 5, and 10 years was 99%, 97%,and 94%, respectively.ConclusionWhile the specific type and size of graft used in valve-sparing aortic root replacement appears to matter less than meticulous technique and valve assessment, our series of 185 patients undergoing a modified David V procedure shows favorable early and midterm results.</p>","PeriodicalId":35950,"journal":{"name":"ASIAN CARDIOVASCULAR & THORACIC ANNALS","volume":" ","pages":"329-337"},"PeriodicalIF":0.7000,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ASIAN CARDIOVASCULAR & THORACIC ANNALS","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/02184923261433401","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/4/16 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
IntroductionReplacement of the aortic root with a composite valve-graft and coronary reimplantation is the most widely performed operation for patients requiring aortic root replacement; however valve sparing operations have been developed to preserve the aortic valve in certain populations. Since they were first introduced, the remodeling and reimplantation techniques have undergone many refinements and modifications. We describe the technical steps and outcomes of a modified David V procedure, adapted from the Stanford modification, performed at our institution.MethodsBetween November 2007 and March 2025, 417 patients underwent valve-sparing aortic root replacement at our institution. Of those, 185 patients underwent an adapted Stanford modification of valve-sparing aortic root replacement. A retrospective review of these patients was performed from a prospectively maintained institutional database.ResultsMean age was 47.6 ± 15.7 years and 81% were male. About 20.5% of patients had a heritable thoracic aortic disorder and 22.1% had a bicuspid aortic valve. The technique of our modified David V procedure is described. There was one post-operative mortality (0.5%) and no 30-day reinterventions. Early postoperative echocardiographic follow-up within 90 days was available in 91% of patients (n = 168), with no cases of greater than moderate aortic insufficiency. Survival at 1, 5, and 10 years was 99%, 98%, and 92%, respectively. Freedom from aortic valve or aortic re-operation at 1, 5, and 10 years was 99%, 97%,and 94%, respectively.ConclusionWhile the specific type and size of graft used in valve-sparing aortic root replacement appears to matter less than meticulous technique and valve assessment, our series of 185 patients undergoing a modified David V procedure shows favorable early and midterm results.
期刊介绍:
The Asian Cardiovascular and Thoracic Annals is an international peer-reviewed journal pertaining to cardiovascular and thoracic medicine. Besides original clinical manuscripts, we welcome research reports, product reviews, reports of new techniques, and findings of special significance to Asia and the Pacific Rim. Case studies that have significant novel original observations, are instructive, include adequate methodological details and provide conclusions. Workshop proceedings, meetings and book reviews, letters to the editor, and meeting announcements are encouraged along with relevant articles from authors.