A modified David V: Technique and outcomes from a large single centre experience.

IF 0.7 Q3 Medicine
ASIAN CARDIOVASCULAR & THORACIC ANNALS Pub Date : 2026-05-01 Epub Date: 2026-04-16 DOI:10.1177/02184923261433401
Robert Fleck, Melissa G Medina, Christopher K Mehta, Beth Whippo, Yunda Wang, Anirudha S Chandrabhatla, Kira Gerweck, Meilynn Shi, S Chris Malaisrie
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引用次数: 0

Abstract

IntroductionReplacement of the aortic root with a composite valve-graft and coronary reimplantation is the most widely performed operation for patients requiring aortic root replacement; however valve sparing operations have been developed to preserve the aortic valve in certain populations. Since they were first introduced, the remodeling and reimplantation techniques have undergone many refinements and modifications. We describe the technical steps and outcomes of a modified David V procedure, adapted from the Stanford modification, performed at our institution.MethodsBetween November 2007 and March 2025, 417 patients underwent valve-sparing aortic root replacement at our institution. Of those, 185 patients underwent an adapted Stanford modification of valve-sparing aortic root replacement. A retrospective review of these patients was performed from a prospectively maintained institutional database.ResultsMean age was 47.6 ± 15.7 years and 81% were male. About 20.5% of patients had a heritable thoracic aortic disorder and 22.1% had a bicuspid aortic valve. The technique of our modified David V procedure is described. There was one post-operative mortality (0.5%) and no 30-day reinterventions. Early postoperative echocardiographic follow-up within 90 days was available in 91% of patients (n = 168), with no cases of greater than moderate aortic insufficiency. Survival at 1, 5, and 10 years was 99%, 98%, and 92%, respectively. Freedom from aortic valve or aortic re-operation at 1, 5, and 10 years was 99%, 97%,and 94%, respectively.ConclusionWhile the specific type and size of graft used in valve-sparing aortic root replacement appears to matter less than meticulous technique and valve assessment, our series of 185 patients undergoing a modified David V procedure shows favorable early and midterm results.

修改后的David V:大型单中心经验的技术和结果。
导论:主动脉根部置换术采用复合瓣膜移植物和冠状动脉再植术是需要主动脉根部置换术的患者最常用的手术;然而,在某些人群中,保留主动脉瓣的手术已经发展起来。自首次引入以来,重塑和再植技术经历了许多改进和修改。我们描述了修改后的David V手术的技术步骤和结果,该手术改编自斯坦福大学的修改,在我们机构进行。方法:2007年11月至2025年3月,417例患者在我院接受了保留瓣膜的主动脉根部置换术。其中,185名患者接受了斯坦福改良的保留瓣膜的主动脉根部置换术。从前瞻性维护的机构数据库中对这些患者进行回顾性审查。结果:平均年龄47.6±15.7岁,男性占81%。约20.5%的患者患有遗传性胸主动脉疾病,22.1%的患者患有双尖瓣主动脉瓣。介绍了我们改良的大卫V法的技术。1例术后死亡率(0.5%),无30天再干预。91%的患者(n = 168)在术后90天内进行了早期超声心动图随访,没有超过中度的主动脉不全病例。1年、5年和10年生存率分别为99%、98%和92%。术后1年、5年和10年主动脉瓣置换率分别为99%、97%和94%。结论:尽管保留瓣膜的主动脉根置换术中使用的移植物的具体类型和大小似乎比细致的技术和瓣膜评估更重要,但我们对185名接受改良David V手术的患者进行的研究显示了良好的早期和中期结果。
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来源期刊
CiteScore
1.30
自引率
0.00%
发文量
78
期刊介绍: The Asian Cardiovascular and Thoracic Annals is an international peer-reviewed journal pertaining to cardiovascular and thoracic medicine. Besides original clinical manuscripts, we welcome research reports, product reviews, reports of new techniques, and findings of special significance to Asia and the Pacific Rim. Case studies that have significant novel original observations, are instructive, include adequate methodological details and provide conclusions. Workshop proceedings, meetings and book reviews, letters to the editor, and meeting announcements are encouraged along with relevant articles from authors.
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