Intraoperative respiratory exchange ratio to predict complications after cardiopulmonary bypass surgery: a retrospective cohort study.

IF 2.6 3区医学 Q2 ANESTHESIOLOGY

Journal of Clinical Monitoring and Computing Pub Date : 2026-08-01 Epub Date: 2026-04-15 DOI:10.1007/s10877-026-01436-w

Sophia Riesemann, Luca J Wachtendorf, Ben L P Braeuer, Sebastian D Sahli, Béla-Simon Paschold, Theresa Tenge, Carsten Marcus, Peter Santer, Robina Matyal, Maximilian S Schaefer, Mark J Robitaille

引用次数: 0

查看原文本刊更多论文

术中呼吸交换率预测体外循环术后并发症：一项回顾性队列研究。

呼吸交换比（RER），定义为二氧化碳（CO2）产生与氧气（O2）消耗的比率，可能是一种无创且可连续测量的替代乳酸的方法，用于识别非心脏手术中有术后并发症风险的患者。我们研究了术中RER是否能预测心脏手术中血乳酸水平和术后并发症。这项回顾性队列研究包括2008年至2020年间在美国波士顿Beth Israel Deaconess医疗中心接受心脏手术和体外循环的成年患者。分析术中吸入和呼气CO2、O2分分钟数据。使用单变量和优先定义的多变量logistic回归模型来评估手术中位RER、术中乳酸和术后7天主要并发症之间的关系（欧洲围手术期临床结局定义）。纳入4058例患者的324646例RER计算。1745例（43.0%）患者出现术后7天并发症。旁路术前和术后的中位（IQR） RER分别为0.64（0.48-0.92）和0.65（0.48-0.97）。乳酸检测前10分钟内的RER与乳酸水平bb0.2 mmol/l相关（调整优势比[ORadj] 1.11, 95%可信区间[CI] 1.01-1.23, p = 0.031）。搭桥前后RER均与术后7天并发症无关（搭桥前：ORadj 1.02, 95%CI 0.95-1.10, p = 0.55；搭桥后：ORadj 1.03, 95%CI 0.95-1.13, p = 0.46）。虽然RER显示出与高乳酸血症的适度关系，但其作为术后并发症预测指标的效用在实际数据中似乎有限。需要进一步的研究来阐明其作用和临床应用的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Clinical Monitoring and Computing ANESTHESIOLOGY-

CiteScore

4.30

自引率

13.60%

发文量

144

审稿时长

6-12 weeks

期刊介绍： The Journal of Clinical Monitoring and Computing is a clinical journal publishing papers related to technology in the fields of anaesthesia, intensive care medicine, emergency medicine, and peri-operative medicine. The journal has links with numerous specialist societies, including editorial board representatives from the European Society for Computing and Technology in Anaesthesia and Intensive Care (ESCTAIC), the Society for Technology in Anesthesia (STA), the Society for Complex Acute Illness (SCAI) and the NAVAt (NAVigating towards your Anaestheisa Targets) group. The journal publishes original papers, narrative and systematic reviews, technological notes, letters to the editor, editorial or commentary papers, and policy statements or guidelines from national or international societies. The journal encourages debate on published papers and technology, including letters commenting on previous publications or technological concerns. The journal occasionally publishes special issues with technological or clinical themes, or reports and abstracts from scientificmeetings. Special issues proposals should be sent to the Editor-in-Chief. Specific details of types of papers, and the clinical and technological content of papers considered within scope can be found in instructions for authors.