Efficacy of Dental Varnishes and Gels for the Prevention and Management of Dental Caries in Older Adults-A Systematic Review and Meta-Analysis.

IF 1.6 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE
Gerodontology Pub Date : 2026-04-15 DOI:10.1111/ger.70075
Theresa Cleary, Enas M Rostom, Reyes Enciso, Roseann Mulligan
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引用次数: 0

Abstract

Introduction: To evaluate the efficacy of dental varnishes/gels in the prevention/management of dental caries in older adults.

Methods: Cochrane, PubMed, Web of Science and EMBASE were searched through March 2024 for randomized controlled trials (RCT) including patients aged ≥ 60 years (or average age ≥ 60 years) utilizing varnish or gel interventions. Outcomes included caries incidence and lesion progression or reversal.

Results: Of 112 abstracts reviewed, 10 RCTs (unclear or high risk of bias) were included. One study showed 1% chlorhexidine (CHX)-1% thymol varnish applied 7 times over 12 months significantly reduced carious/filled surfaces versus placebo (p < 0.001) and improved active lesions (RR = 2.00, p = 0.018). Monthly 5% sodium fluoride (NaF) varnish with professional brushing significantly improved outcomes versus standard fluoride toothpaste and oral hygiene instructions [OHI] (RR = 1.63, p = 0.002). When professional cleaning and OHI were provided quarterly, adding varnishes (1% CHX-1% thymol or 5% NaF) showed no significant additional benefit. Evidence quality was low to moderate due to heterogeneity and bias.

Conclusion: Quarterly professional cleaning with OHI was as efficacious as adding either the 1% CHX-1% thymol or 5% NaF varnishes. Applying dental varnishes in the office every 3 months could be a more practical option for the delivery of preventive modalities to older adults who could have cognitive or physical limitations that negatively impact the frequency of daily or weekly use at home of toothpaste or rinses. Future research should evaluate cost-effectiveness and adherence to preventive protocols across different patient functional and behavioural abilities and care settings.

Trial registration: PROSPERO ID: CRD42024585284.

牙齿清漆和牙胶预防和治疗老年人龋齿的疗效——系统综述和荟萃分析。
前言:评价牙齿清漆/凝胶预防/处理老年人龋齿的效果。方法:检索Cochrane、PubMed、Web of Science和EMBASE截至2024年3月的随机对照试验(RCT),包括年龄≥60岁(或平均年龄≥60岁)使用清漆或凝胶干预的患者。结果包括龋齿发生率、病变进展或逆转。结果:在112篇综述中,纳入了10项随机对照试验(不明确或高偏倚风险)。一项研究表明,与安慰剂相比,在12个月内使用7次1%氯己定-1%百里香酚清漆可显著减少龋齿/填充表面(p结论:每季度使用OHI进行专业清洁与添加1% CHX-1%百里香酚或5% NaF清漆一样有效。每3个月在办公室涂一次牙齿清漆,对于那些可能有认知或身体限制的老年人来说,这对每天或每周在家使用牙膏或漱口水的频率产生负面影响,是一种更实际的预防方式。未来的研究应评估不同患者功能和行为能力以及护理环境下预防方案的成本效益和依从性。试验注册:PROSPERO ID: CRD42024585284。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Gerodontology
Gerodontology 医学-老年医学
CiteScore
4.10
自引率
10.00%
发文量
50
审稿时长
3-6 weeks
期刊介绍: The ultimate aim of Gerodontology is to improve the quality of life and oral health of older people. The boundaries of most conventional dental specialties must be repeatedly crossed to provide optimal dental care for older people. In addition, management of other health problems impacts on dental care and clinicians need knowledge in these numerous overlapping areas. Bringing together these diverse topics within one journal serves clinicians who are seeking to read and to publish papers across a broad spectrum of specialties. This journal provides the juxtaposition of papers from traditional specialties but which share this patient-centred interest, providing a synergy that serves progress in the subject of gerodontology.
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