Management of Gastric Cancer Peritoneal Metastasis: IGCA Working Group Consensus Statements.

IF 9.4 1区医学 Q1 SURGERY

British Journal of Surgery Pub Date : 2026-03-17 DOI:10.1093/bjs/znag027

Piers R Boshier,Daryl Kai Ann Chia,Sri Ganeshamurthy Thrumurthy,Jun Liang Teh,Maria Wobith,Maria Bencivenga,Federica Filippini,Teodora Dumitra,Miguel Burch,Hyoung-Il Kim,Benjamin Kobitzsch,Liudmila L Kodach,Judith S E Quik,Vo Duy Long,Micha J de Neijs,Pieter C van der Sluis,Alberto M Leon-Takahashi,Yanghee Woo,Mickael Chevallay,Massimo Framarini,Paolo Morgagni,Ewelina Frejlich,Heike I Grabsch,Sheraz R Markar,Daniele Marrelli,Do Joong Park,Raghav Sundar,Zekuan Xu,Kay Khine Linn,Han Kwang Yang,Joji Kitayama,Zhenggang Zhu,Sun Young Rha,Bas Wijnhoven,Hiroharu Yamashita,Wei Peng Yong,Christelle de la Fouchardière,Magnus Nilsson,Hironori Ishigami,Johanna W Van Sandick,Florian Lordick,Brian D Badgwell,Jimmy Bok-Yan So

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引用次数: 0

Abstract

INTRODUCTION Gastric cancer peritoneal metastasis (GCPM) is a common manifestation of advanced gastric cancer, associated with poor prognosis. METHODS The International Gastric Cancer Association (IGCA) convened a multidisciplinary working group of 42 global experts from 15 countries to develop a total of thirteen consensus statements addressing diagnosis, treatment, and research priorities for GCPM. Using ACCORD-compliant methodology, the group conducted systematic literature searches and applied a structured Delphi process with anonymous Likert-scale voting and ≥70% consensus threshold to generate and refine consensus statements. RESULTS Consensus was achieved for all thirteen statements among the working group during the first Delphi round with 75-100% of respondents selecting either "Strongly Agree" or "Agree". Coefficients of variation values were ≤ 0.23. Polling of a broader group of experts (n=63) that included members of the working group (n=21) during the IGCC (2025) GCPM Consensus Session demonstrated agreement for twelve of the thirteen statements. This broader group of experts, that had greater representation from medical oncologists, did not reach consensus (52% agreement) on best practice for systemic treatment of patients with GCPM, possibly due the rapidly evolving developments in this field of metastatic gastric cancer. CONCLUSION This consensus exercise provides a foundation for globally relevant GCPM management strategies and highlights critical research needed to address significant evidence gaps that will improve patient outcomes.

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胃癌腹膜转移的治疗：IGCA工作组共识声明。

胃癌腹膜转移（GCPM）是晚期胃癌的常见表现，预后较差。方法国际胃癌协会（IGCA）召集了一个由来自15个国家的42位全球专家组成的多学科工作组，针对GCPM的诊断、治疗和研究重点制定了13项共识声明。采用符合accord标准的方法，研究小组进行了系统的文献检索，并采用结构化的德尔菲过程，采用匿名李克特量表投票和≥70%的共识阈值来生成和完善共识陈述。结果在第一轮德尔菲轮中，工作组对所有13项声明达成了共识，75% -100%的受访者选择“强烈同意”或“同意”。变异值系数≤0.23。在IGCC (2025) GCPM协商一致会议期间，对包括工作组成员（n=21）在内的更广泛专家组（n=63）进行的民意调查显示，对13项声明中的12项表示同意。这个更广泛的专家组，有更多来自医学肿瘤学家的代表，没有就GCPM患者全身治疗的最佳实践达成共识（52%的同意），可能是由于转移性胃癌领域的快速发展。结论：这一共识练习为全球相关的GCPM管理策略提供了基础，并强调了解决重大证据差距所需的关键研究，这将改善患者的预后。

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来源期刊

British Journal of Surgery 医学-外科

CiteScore

12.70

自引率

7.30%

发文量

1102

审稿时长

1.5 months

期刊介绍： The British Journal of Surgery (BJS), incorporating the European Journal of Surgery, stands as Europe's leading peer-reviewed surgical journal. It serves as an invaluable platform for presenting high-quality clinical and laboratory-based research across a wide range of surgical topics. In addition to providing a comprehensive coverage of traditional surgical practices, BJS also showcases emerging areas in the field, such as minimally invasive therapy and interventional radiology. While the journal appeals to general surgeons, it also holds relevance for specialty surgeons and professionals working in closely related fields. By presenting cutting-edge research and advancements, BJS aims to revolutionize the way surgical knowledge is shared and contribute to the ongoing progress of the surgical community.