Minimally invasive direct screw fixation of Jefferson fractures: A case series and technical note

Neurocirugia (English Edition) Pub Date : 2026-07-01 Epub Date: 2026-03-20 DOI:10.1016/j.neucie.2026.500766
Ivan Lvov, Andrey Grin, Anton Kordonskiy, Zaali Barbakadze, Aleksandr Talypov, Aleksandr Tupikin
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Abstract

Objective

To demonstrate the feasibility of a minimally invasive technique for direct C1 screw fixation and to evaluate short- and long-term clinical and radiological outcomes in a case series.

Materials and methods

This study included a consecutive series of patients with type II or III fractures of the C1 vertebra according to the Landells classification. The surgical technique is described in detail, along with short- and long-term outcomes. Owing to the absence of comparison groups, only descriptive statistical methods were used.

Results

This case series included 8 patients (5 men and 3 women; mean age, 50.8 ± 20.0 years). All patients were neurologically intact at presentation. Most patients had concomitant transverse atlantal ligament injury or associated unstable spinal trauma. The mean operative time was 216.3 ± 100.3 min, and the mean intraoperative blood loss was 125.0 ± 71.5 mL. Seven patients were discharged with clinical improvement, whereas 1 patient died on postoperative day 11 due to severe pneumonia and concomitant injury.
Six patients were available for final assessment. The mean follow-up duration was 39.7 ± 31.2 months. The mean VAS score was 2.2 ± 1.1, and the mean NDI score was 6.8 ± 3.0. Solid fusion was achieved in all patients. No implant-related complications were observed. In five patients, no degenerative changes were detected in the C1-C2 lateral joints, whereas one patient showed grade 2 degenerative changes.

Conclusion

Our initial clinical experience suggests that minimally invasive posterior direct C1 screw fixation is a feasible and safe procedure, providing consistently favourable clinical outcomes in this case series. This technique allowed optimal screw trajectories to be achieved without additional tissue trauma or widening of the surgical exposure. Its application enabled preservation of C1-C2 segmental mobility in all patients included in this series.
微创直接C1螺钉固定杰弗逊骨折:一个病例系列和技术说明。
目的:通过一个病例系列来证明微创技术直接C1螺钉固定的可行性,并评估短期和长期的临床和放射学结果。材料和方法:本研究纳入了根据Landells分类的连续系列II型或III型C1椎体骨折患者。详细描述了手术技术,以及短期和长期的结果。由于没有对照组,只采用描述性统计方法。结果:本组病例共8例,男5例,女3例,平均年龄50.8±20.0岁。所有患者在就诊时神经功能完好。大多数患者伴有横向寰韧带损伤或不稳定脊柱损伤。平均手术时间216.3±100.3 min,平均术中出血量125.0±71.5 mL。7例患者临床好转出院,1例患者术后第11天因严重肺炎并发损伤死亡。6例患者可进行最终评估。平均随访时间39.7±31.2个月。VAS评分平均为2.2±1.1分,NDI评分平均为6.8±3.0分。所有患者均实现了固体融合。未观察到种植体相关并发症。在5例患者中,C1-C2侧关节未发现退行性改变,而1例患者出现2级退行性改变。结论:我们的初步临床经验表明,微创后路直接C1螺钉固定是可行且安全的手术,在本病例系列中提供了一致的良好临床结果。该技术允许在没有额外组织损伤或扩大手术暴露的情况下实现最佳螺钉轨迹。它的应用使本系列中所有患者的C1-C2节段活动得以保留。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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