{"title":"Unmet needs and quality of life in first-stroke patients: The mediating effects of activities of daily living, depression, and social support.","authors":"Chang Gao, Fanling Li, Yan Qu, Xiaohong Hu, Wenxuan Ding, Xiaomei Li, Jingjun Zhang","doi":"10.1016/j.dhjo.2026.102071","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Stroke is a primary cause of disability on a global scale. The resultant functional impairments consequent to stroke give rise to a range of unmet needs among patients, especially those experiencing their first stroke. The unmet needs of patients may have a significant negative impact on their quality of life (QoL). However, the mechanisms underlying this relationship remain poorly understood.</p><p><strong>Objective: </strong>Examine the mediating effects of activities of daily living (ADL), depression, and social support on the relationship between unmet needs and QoL in first-stroke patients.</p><p><strong>Methods: </strong>A convenience sample of 400 patients with first-ever stroke was recruited. Data were collected using the Longer-term Unmet Needs after Stroke monitoring tool, the Barthel Index, the Patient Health Questionnaire-9, the Social Support Rating Scale, and the Stroke-Specific Quality of Life Scale. A parallel mediation analysis was conducted using Model 4 of the SPSS PROCESS macro.</p><p><strong>Results: </strong>The results showed that unmet needs were negatively correlated with QoL. The mediation analysis revealed a significant direct effect of unmet needs on QoL, as well as indirect effects through ADL and depression. Social support did not show a significant mediating effect.</p><p><strong>Conclusion: </strong>Unmet needs affect QoL both directly and indirectly through ADL and depression. These findings underscore the importance of routine assessment and targeted management of unmet needs during post-stroke care. Interventions aimed at enhancing physical functioning and alleviating depression may be effective strategies to improve QoL in this population.</p>","PeriodicalId":49300,"journal":{"name":"Disability and Health Journal","volume":" ","pages":"102071"},"PeriodicalIF":3.3000,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Disability and Health Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.dhjo.2026.102071","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Stroke is a primary cause of disability on a global scale. The resultant functional impairments consequent to stroke give rise to a range of unmet needs among patients, especially those experiencing their first stroke. The unmet needs of patients may have a significant negative impact on their quality of life (QoL). However, the mechanisms underlying this relationship remain poorly understood.
Objective: Examine the mediating effects of activities of daily living (ADL), depression, and social support on the relationship between unmet needs and QoL in first-stroke patients.
Methods: A convenience sample of 400 patients with first-ever stroke was recruited. Data were collected using the Longer-term Unmet Needs after Stroke monitoring tool, the Barthel Index, the Patient Health Questionnaire-9, the Social Support Rating Scale, and the Stroke-Specific Quality of Life Scale. A parallel mediation analysis was conducted using Model 4 of the SPSS PROCESS macro.
Results: The results showed that unmet needs were negatively correlated with QoL. The mediation analysis revealed a significant direct effect of unmet needs on QoL, as well as indirect effects through ADL and depression. Social support did not show a significant mediating effect.
Conclusion: Unmet needs affect QoL both directly and indirectly through ADL and depression. These findings underscore the importance of routine assessment and targeted management of unmet needs during post-stroke care. Interventions aimed at enhancing physical functioning and alleviating depression may be effective strategies to improve QoL in this population.
期刊介绍:
Disability and Health Journal is a scientific, scholarly, and multidisciplinary journal for reporting original contributions that advance knowledge in disability and health. Topics may be related to global health, quality of life, and specific health conditions as they relate to disability. Such contributions include:
• Reports of empirical research on the characteristics of persons with disabilities, environment, health outcomes, and determinants of health
• Reports of empirical research on the Systematic or other evidence-based reviews and tightly conceived theoretical interpretations of research literature
• Reports of empirical research on the Evaluative research on new interventions, technologies, and programs
• Reports of empirical research on the Reports on issues or policies affecting the health and/or quality of life for persons with disabilities, using a scientific base.