Respiratory variation in carotid artery blood flow peak velocity combined with tidal volume challenge in predicting fluid responsiveness of lung-protective ventilation patients: a feasibility study.

IF 2.6 3区医学 Q2 ANESTHESIOLOGY

Journal of Clinical Monitoring and Computing Pub Date : 2026-08-01 Epub Date: 2026-03-14 DOI:10.1007/s10877-026-01429-9

Xiaoying Wang, Qun Zhou, Jingqi Ma, Ju Gao, Tianfeng Huang

引用次数: 0

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颈动脉血流峰值速度的呼吸变化结合潮气量挑战预测肺保护通气患者的液体反应性：可行性研究

动态指标对麻醉过程中的液体管理具有较高的可预测性。然而，作为新兴的肺保护策略概念，由于胸内压力和预负荷变化不足，动态指标在低潮气量（Vt）的应用范围受到限制。潮气量挑战（Tidal volume challenge， TVC）作为一种功能工具，已被证明可以帮助动态指标解决低Vt困境。本研究旨在探讨颈动脉血流量峰值速度呼吸变化（ΔVpeak-CA）结合TVC评估全身麻醉下肺保护通气患者的液体反应性的可行性和准确性。我们在插管后实施肺保护策略，包括低Vt、PEEP滴定和必要时的开肺入路。我们在完成个体肺保护设置后实施TVC。不久之后进行液体刺激（FC），我们将液体反应性定义为心脏指数(CI)≥15%。分别在TVC前（T1）、TVC结束时间点（T2）、FC前（T3）和FC后（T4）采集血流动力学数据。最后，我们招募了74例接受腹部大开腹手术的患者，其中45例有液体反应。我们发现TVC提高了ΔVpeak-CA的可预测性，ΔVpeak-CA t2和ΔVpeak-CA T1之间的AUC差异显著（0.162,p = 0.0052）。ΔVpeak-CA T2比ΔVpeak-CA T2- T1更准确，更容易评估，AUC最高，为0.897 （0.619 - 0.830）

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Clinical Monitoring and Computing ANESTHESIOLOGY-

CiteScore

4.30

自引率

13.60%

发文量

144

审稿时长

6-12 weeks

期刊介绍： The Journal of Clinical Monitoring and Computing is a clinical journal publishing papers related to technology in the fields of anaesthesia, intensive care medicine, emergency medicine, and peri-operative medicine. The journal has links with numerous specialist societies, including editorial board representatives from the European Society for Computing and Technology in Anaesthesia and Intensive Care (ESCTAIC), the Society for Technology in Anesthesia (STA), the Society for Complex Acute Illness (SCAI) and the NAVAt (NAVigating towards your Anaestheisa Targets) group. The journal publishes original papers, narrative and systematic reviews, technological notes, letters to the editor, editorial or commentary papers, and policy statements or guidelines from national or international societies. The journal encourages debate on published papers and technology, including letters commenting on previous publications or technological concerns. The journal occasionally publishes special issues with technological or clinical themes, or reports and abstracts from scientificmeetings. Special issues proposals should be sent to the Editor-in-Chief. Specific details of types of papers, and the clinical and technological content of papers considered within scope can be found in instructions for authors.