A Retrospective Study of Mood and Anxiety Disorders Management Profile (MooD-MaP) of Patients Admitted at the Makati Medical Center from 2014-2017.

Carmina Charmaine G Bernardo, Elaine Angela O Leynes, Sophia Grace Benosa, Lorraine Freyja Linsangan, Robin Myan Dantes, Vichka Claire Sison, Ormalyn Bayting
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Abstract

Mood and anxiety disorders are leading causes of psychiatric hospitalization. However, data on real-world inpatient psychopharmacologic practices in the Philippines are limited. This study aims to describe the clinical characteristics and psychotropic medication prescribing patterns among inpatients with mood and anxiety disorders at a tertiary private hospital in the Philippines. This retrospective descriptive study reviewed medical records of patients admitted to the Section of Psychiatry at Makati Medical Center from January 1, 2014, to December 31, 2017. Patients with a primary DSM-5 diagnosis of bipolar disorder (BD), major depressive disorder (MDD), or anxiety disorder (AD) were included. Demographic and clinical characteristics, suicidality, and psychotropic prescribing patterns were summarized using descriptive statistics. A total of 705 patients were included: 350 (49.6%) with BD, 301 (42.7%) with MDD, and 54 (7.7%) with AD. Depressed mood was the most common presentation at admission (58.6%), and 72.2% of patients were euthymic at discharge. Suicide attempts were documented in more than half of patients with available data. Valproate, quetiapine, clonazepam, and aripiprazole were the most frequently prescribed medications for BD. In MDD, clonazepam, escitalopram, quetiapine, and aripiprazole predominated, while clonazepam and selective serotonin reuptake inhibitors were most commonly used in AD. Polypharmacy was frequent across diagnostic groups. Psychopharmacologic management of hospitalized patients with mood and anxiety disorders in this Philippine tertiary center largely aligns with international practice. High rates of polypharmacy and suicidality underscore the need for optimized, evidence-based prescribing and longitudinal outcome studies.

2014-2017年马卡蒂医疗中心入院患者情绪和焦虑障碍管理概况(Mood - map)的回顾性研究
情绪和焦虑障碍是精神病住院的主要原因。然而,关于菲律宾现实世界住院患者精神药理学实践的数据有限。本研究旨在描述菲律宾一家三级私立医院情绪和焦虑障碍住院患者的临床特征和精神药物处方模式。本回顾性描述性研究回顾了2014年1月1日至2017年12月31日在马卡蒂医疗中心精神科住院的患者的医疗记录。在DSM-5中诊断为双相情感障碍(BD)、重度抑郁症(MDD)或焦虑症(AD)的患者被纳入研究。人口统计学和临床特征、自杀倾向和精神药物处方模式用描述性统计进行总结。共纳入705例患者:BD患者350例(49.6%),MDD患者301例(42.7%),AD患者54例(7.7%)。抑郁情绪是入院时最常见的表现(58.6%),72.2%的患者出院时心境良好。有资料显示,超过一半的病人有自杀企图。丙戊酸、喹硫平、氯硝西泮和阿立哌唑是治疗双相障碍最常用的处方药。在重度抑郁症中,氯硝西泮、艾司西酞普兰、喹硫平和阿立哌唑占主导地位,而氯硝西泮和选择性5 -羟色胺再摄取抑制剂最常用于AD。多药在诊断组中很常见。精神药理学管理住院患者的情绪和焦虑障碍在这个菲律宾三级中心很大程度上与国际惯例一致。多种用药和自杀的高发生率强调了优化、循证处方和纵向结果研究的必要性。
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