He Zhang, Md Maksudur Rahman, Yang Tao, Joseph W Sampson, Hang Ren
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引用次数: 0
Abstract
Nanopipette based scanning probe technique is a versatile tool in non-contact imaging in biology. In addition to the topographic imaging, its capability of localized delivery of bio-active molecules is emerging. In this mini review, we introduce the applications of nanopipette in single-cell researches with a focus on localized delivery. The working principles of three delivery modes including resistive pulse, pressure-driven flow, and electroosmotic flow-driven delivery are summarized and compared. Their applications in single-cell researches are reviewed. The current technical challenges in scanning ion conductance microscopy-based delivery, and their growing influence in medicine and pharmacologic researches are also discussed.
期刊介绍：
The journal "Electrochemistry (Chinese and English)" is an academic journal supervised by the China Association for Science and Technology, co-sponsored by the Chinese Chemical Society and Xiamen University, and co-sponsored by the State Key Laboratory of Physical Chemistry of Solid Surfaces of Xiamen University, Huizhou Yiwei Lithium Energy Co., Ltd., and the National Engineering Research Center for Electrochemical Energy Storage Technology. It is publicly distributed at home and abroad, aiming to timely reflect the latest scientific research results and trends in the field of electrochemistry in my country and promote academic exchanges at home and abroad. It has columns such as review, research papers, and research briefs.
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