MyADHD: A therapist-guided internet-delivered intervention for adult ADHD — Results from a single-armed open clinical trial in routine care

IF 4.1 2区医学 Q1 HEALTH CARE SCIENCES & SERVICES

Internet Interventions-The Application of Information Technology in Mental and Behavioural Health Pub Date : 2026-06-01 Epub Date: 2026-03-02 DOI:10.1016/j.invent.2026.100922

Aleksander Heltne , Robin Maria Francisca Kenter , Robin Gulseth , Tine Nordgreen

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引用次数: 0

Abstract

Background

Adults seeking treatment for the syndrome of ADHD often face barriers to accessing evidence-based care. Digital interventions may help address these challenges, but their effectiveness in routine clinical settings remains underexplored.

Objective

This study evaluated pre–post change in ADHD symptoms and quality of life following a therapist-guided internet-delivered intervention for adults with ADHD in routine care. A secondary aim was to examine demographic, contextual, and clinical predictors of treatment response.

Methods

In an open, single-arm trial, 228 adults with ADHD received a 7–10 week therapist-guided intervention. ADHD symptoms (Adult ADHD Self-Report Scale; ASRS) and quality of life (Adult ADHD Quality of Life questionnaire; AAQoL) were assessed at baseline, mid-treatment, and post-treatment. Random intercept, fixed slope linear mixed models were estimated to examine change over time and impact of potential predictors.

Results

Participants showed moderate improvements in ADHD symptoms (d = −0.47) and quality of life (d = 0.45). Inattention and productivity domains improved most. Reliable change was observed in 23.9% of completers for ADHD symptoms and 31.0% for quality of life. No demographic, contextual, or clinical variables significantly predicted treatment response.

Conclusions

In this open, single-arm study conducted in routine clinical care, therapist-guided internet-delivered treatment was associated with moderate improvements in ADHD symptoms and quality of life among adults with ADHD. Findings were comparable across baseline levels of comorbidity, treatment expectation and route to care. Given the absence of a control group, findings should be interpreted cautiously, and causal inferences cannot be drawn. Replication in adequately powered randomized controlled trials is needed to determine the intervention's efficacy and to clarify for whom and under what conditions it is most effective.

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MyADHD：一种治疗师引导的成人ADHD网络干预——来自常规护理的单臂开放临床试验的结果

背景：寻求ADHD综合征治疗的成年人常常面临获得循证治疗的障碍。数字干预可能有助于解决这些挑战，但其在常规临床环境中的有效性仍未得到充分探索。目的：本研究评估在常规护理中对成人ADHD患者进行治疗师指导的网络干预后，ADHD症状和生活质量的前后变化。第二个目的是检查治疗反应的人口学、环境和临床预测因素。方法在一项开放的单臂试验中，228名ADHD成人患者接受了为期7-10周的治疗师指导干预。在基线、治疗中和治疗后分别评估ADHD症状（成人ADHD自我报告量表；ASRS）和生活质量（成人ADHD生活质量问卷；AAQoL）。估计随机截距，固定斜率线性混合模型，以检查随时间的变化和潜在预测因子的影响。结果受试者ADHD症状（d = - 0.47）和生活质量（d = 0.45）均有中度改善。注意力不集中和效率提高最多。在23.9%的ADHD症状完成者和31.0%的生活质量完成者中观察到可靠的变化。没有人口统计学、背景或临床变量显著预测治疗反应。结论：在这项在常规临床护理中进行的开放单臂研究中，治疗师指导的网络传递治疗与ADHD成人患者的ADHD症状和生活质量的中度改善相关。研究结果在合并症、治疗预期和护理途径的基线水平上具有可比性。由于没有对照组，研究结果应谨慎解释，不能得出因果推论。需要在足够有力的随机对照试验中进行重复试验，以确定干预措施的有效性，并阐明对谁以及在什么条件下干预措施最有效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Internet Interventions-The Application of Information Technology in Mental and Behavioural Health Medicine-Health Informatics

CiteScore

6.50

自引率

9.30%

发文量

审稿时长

6 weeks

期刊介绍： Official Journal of the European Society for Research on Internet Interventions (ESRII) and the International Society for Research on Internet Interventions (ISRII). The aim of Internet Interventions is to publish scientific, peer-reviewed, high-impact research on Internet interventions and related areas. Internet Interventions welcomes papers on the following subjects: • Intervention studies targeting the promotion of mental health and featuring the Internet and/or technologies using the Internet as an underlying technology, e.g. computers, smartphone devices, tablets, sensors • Implementation and dissemination of Internet interventions • Integration of Internet interventions into existing systems of care • Descriptions of development and deployment infrastructures • Internet intervention methodology and theory papers • Internet-based epidemiology • Descriptions of new Internet-based technologies and experiments with clinical applications • Economics of internet interventions (cost-effectiveness) • Health care policy and Internet interventions • The role of culture in Internet intervention • Internet psychometrics • Ethical issues pertaining to Internet interventions and measurements • Human-computer interaction and usability research with clinical implications • Systematic reviews and meta-analysis on Internet interventions