Are elderly patients undergoing blood transfusion during hip fracture surgery at risk of postoperative delirium: a retrospective observational study.

Q1 Medicine

MUSCULOSKELETAL SURGERY Pub Date : 2026-03-05 DOI:10.1007/s12306-026-00949-6

A Laudisio, B Zampogna, G Francesco Papalia, M Serena Iuorio, F Vorini, P Catania, G Rizzello, R Papalia

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引用次数: 0

Abstract

Purpose: Delirium is common following hip fracture surgery. Red blood cell transfusion (RBCT), which is frequently needed in this population, has been inconsistently associated with incident delirium in previous studies. This study aims to investigate whether RBCT in patients undergoing hip fracture surgery is associated with increased risk of post-operative delirium, and to identify potential risk factors that might influence this association.

Materials and methods: We conducted a retrospective observational study of all hip fracture patients who underwent surgery between November 1 2020 and February 28 2022. Delirium was diagnosed based on DSM V criteria, and assessed daily. The need of perioperative RBCT, and the number of units transfused, were recorded.

Results: A total of 364 participants with a mean age of 84 years were included. Delirium was recorded in 49 (14%) patients, while 88 (24%) required RBCT. In logistic regression, RBCT was associated with delirium (OR = 3.88, 95% CI = 1.23-12.24), after adjusting. An increasing number of RB units transfused was associated with increased probability of delirium (P for linear trend = .013).

Conclusions: Clinicians should carefully consider the indications for RBCT in hip fracture patients. Further studies are needed to confirm these results, and to investigate the potential mechanisms underlying this association.

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在髋部骨折手术中接受输血的老年患者是否有术后谵妄的风险：一项回顾性观察研究

目的：谵妄是髋部骨折术后常见的症状。红细胞输血（RBCT）在这一人群中是经常需要的，在以前的研究中与谵妄事件的关联并不一致。本研究旨在探讨髋部骨折手术患者的RBCT是否与术后谵妄风险增加相关，并确定可能影响这种关联的潜在危险因素。材料和方法：我们对2020年11月1日至2022年2月28日期间接受手术的所有髋部骨折患者进行了回顾性观察研究。谵妄是根据DSM V标准诊断的，并每日进行评估。记录围手术期RBCT需要量及输血单位数。结果：共纳入364名参与者，平均年龄84岁。49例（14%）患者出现谵妄，88例（24%）患者需要RBCT。在逻辑回归中，调整后RBCT与谵妄相关（OR = 3.88, 95% CI = 1.23-12.24）。输血RB单位的增加与谵妄的可能性增加相关（线性趋势P = 0.013）。结论：临床医生应慎重考虑RBCT在髋部骨折患者中的适应症。需要进一步的研究来证实这些结果，并调查这种关联的潜在机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

MUSCULOSKELETAL SURGERY Medicine-Surgery

CiteScore

4.50

自引率

0.00%

发文量

期刊介绍： Musculoskeletal Surgery – Formerly La Chirurgia degli Organi di Movimento, founded in 1917 at the Istituto Ortopedico Rizzoli, is a peer-reviewed journal published three times a year. The journal provides up-to-date information to clinicians and scientists through the publication of original papers, reviews, case reports, and brief communications dealing with the pathogenesis and treatment of orthopaedic conditions.An electronic version is also available at http://www.springerlink.com.The journal is open for publication of supplements and for publishing abstracts of scientific meetings; conditions can be obtained from the Editors-in-Chief or the Publisher.